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(+/-)-THIOPENTAL

(+/-)-THIOPENTAL Structure
CAS No.
76-75-5
Chemical Name:
(+/-)-THIOPENTAL
Synonyms
Intraval;Nesdonal;Thiothal;Pentothal;Tiopentale;THIOPENTAL;Thiomebumal;THIOPENTONE;PENTOTHAL ACID;Thiopental CRS
CBNumber:
CB5265910
Molecular Formula:
C11H18N2O2S
Molecular Weight:
242.34
MOL File:
76-75-5.mol
MSDS File:
SDS
Modify Date:
2023/6/8 13:53:37

(+/-)-THIOPENTAL Properties

Melting point 158-160°C
Density 1.1789 (rough estimate)
refractive index 1.5440 (estimate)
Flash point 11℃
storage temp. 2-8°C
solubility ethanol: complete50mg/mL
pka 7.11±0.40(Predicted)
form Solid
color White to Off-White
Water Solubility 50mg/L(25 ºC)
CAS DataBase Reference 76-75-5(CAS DataBase Reference)
EPA Substance Registry System 4,6(1H,5H)-Pyrimidinedione, 5-ethyldihydro-5-(1-methylbutyl)-2-thioxo- (76-75-5)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P301+P312+P330
Hazard Codes  Xn,T,F
Risk Statements  22-39/23/24/25-23/24/25-11
Safety Statements  36/37/39-45-36/37-16-7
RIDADR  UN 1230 3/PG 2
WGK Germany  3
RTECS  CQ6300000
HazardClass  6.1(b)
PackingGroup  III
HS Code  2933595960
Toxicity cyt-hmn:leu 1500 mg/L TGANAK18(1),13,84

(+/-)-THIOPENTAL Chemical Properties,Uses,Production

Chemical Properties

Off-White Solid

Uses

A thio-derivative of Barbituric acid. Controlled substance (depressant). Anesthetic

Safety Profile

Poison by intraperitoneal, intravenous, and rectal routes. Moderately toxic by ingestion. An experimental teratogen. Human mutation data reported. A short-acting intravenous anesthetic. When heated to decomposition it emits very toxic fumes of NOx and SOx

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5-ETHYL-5-[1-METHYLBUTYL]-2-THIOBARBITURIC ACID 5-ETHYL-5-PENTAN-2-YL-2-SULFANYL-1H-PYRIMIDINE-4,6-DIONE 5-Ethyldihydro-5-(1-methylbutyl)-2-thioxo-4,6(1H,5H)-pyrimidinedione (±)thiopental solution 2-Thio-5-ethyl-5-sec-pentylbarbituric acid 4,6(1H,5H)-Pyrimidinedione, 5-ethyldihydro-5-(1-methylbutyl)-2-thioxo- (9CI) Barbituric acid, 5-ethyl-5-(1-methylbutyl)-2-thio- (8CI) PENTOTHAL ACID 5-Ethyl-5-(1-methylbutyl)-2-thiobarbitirobic acid (+-)-thiopental methanol solution (+,-)-thiopental free acid--dea*schedule iii item 5-Ethyl-5-[(S)-1-methylbutyl]-2-thioxo-1,2-dihydropyrimidine-4,6(3H,5H)-dione Thiopental CIII (250 mg) Thiopental for system suitability Barbituric acid, 5-ethyl-5-(1-methylbutyl)-2-thio- Intraval Nesdonal Penthiobarbital Pentothal Pentothiobarbital Thiomebumal Thiopentobarbital Thiopentobarbitone Thiopentobarbituric acid Thiothal Tiopentale THIOPENTONE (+/-)-THIOPENTAL THIOPENTAL (1h,5h)-pyrimidinedione,5-ethyldihydro-5-(1-methylbutyl)-2-thioxo-6 4,6(1H,5H)-Pyrimidinedione, 5-ethyldihydro-5-(1-methylbutyl)-2-thioxo- 5-ethyl-5-(1-methylbutyl)-2-thio-barbituricaci 5-Ethyl-5-(1-methylbutyl)-2-thioxodihydro-4,6(1H,5H)-pyrimidinedione 5-ethyl-5-pentan-2-yl-2-sulfanylidene-1,3-diazinane-4,6-dione Thiopental CRS Thiopental for system suitability CRS ('+/-)-THIOPENTAL Thiopental for system suitability (Y0001478) 76-75-5 C11H18N2O2S Alphabetic Analytical Chromatography Product Catalog TF - TO Analytical Standards Intermediates & Fine Chemicals Pharmaceuticals