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ChemicalBook > Product Catalog >Biochemical Engineering >Inhibitors >Cell Cycle >Aurora Kinase Inhibitors >MK8745

MK8745

MK8745 Structure
CAS No.
885325-71-3
Chemical Name:
MK8745
Synonyms
MK8745;CS-1904;MK8745 USP/EP/BP;Inhibitor,inhibit,MK8745,Aurora Kinase,MK-8745,MK 8745,Apoptosis;6-[[4-(3-Chloro-2-fluorobenzoyl)piperazin-1-yl]methyl]-N-(thiazol-2-yl)pyridin-2-amine;(3-Chloro-2-fluorophenyl)(4-((6-(thiazol-2-ylamino)pyridin-2-yl)methyl)piperazin-1-yl)methanon;Methanone, (3-chloro-2-fluorophenyl)[4-[[6-(2-thiazolylamino)-2-pyridinyl]methyl]-1-piperazinyl]-;(3-chloro-2-fluorophenyl)(4-((6-(thiazol-2-ylamino)pyridin-2-yl)methyl)piperazin-1-yl)methanone. MK-8745
CBNumber:
CB52668038
Molecular Formula:
C20H19ClFN5OS
Molecular Weight:
431.91
MOL File:
885325-71-3.mol
MSDS File:
SDS
Modify Date:
2023/5/18 11:31:21
Request For Quotation

MK8745 Properties

Melting point 177-179°C
Boiling point 605.5±65.0 °C(Predicted)
Density 1.430±0.06 g/cm3(Predicted)
storage temp. Refrigerator
solubility DMSO (Slightly), Methanol (Slightly, Heated)
form Solid
pka 5.20±0.10(Predicted)
color Off-White

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338

MK8745 Chemical Properties,Uses,Production

Uses

MK-8745 is a potent and selective Aurora A kinase inhibitor that induces apoptotic cell death in a p53-dependent manner when tested in vitro in cell lines of multiple lineages.

MK8745 Preparation Products And Raw materials

Raw materials

Preparation Products

MK8745 Suppliers

Global( 85)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
ATK CHEMICAL COMPANY LIMITED +undefined-21-51877795 China 32835 60 Inquiry
TargetMol Chemicals Inc. +1-781-999-5354 +1-00000000000 United States 19892 58 Inquiry
Dideu Industries Group Limited +86-29-89586680 +86-15129568250 China 23499 58 Inquiry
Zhejiang J&C Biological Technology Co.,Limited +1-2135480471 +1-2135480471 China 10522 58 Inquiry
InvivoChem +1-708-310-1919 +1-13798911105 United States 6393 58 Inquiry
LEAP CHEM CO., LTD. +86-852-30606658 China 24738 58 Inquiry
Nantong HI-FUTURE Biology Co., Ltd. +undefined18051384581 China 3136 58 Inquiry
Wuhan Topule Biopharmaceutical Co., Ltd +8618327326525 China 8474 58 Inquiry
Aladdin Scientific +1-+1(833)-552-7181 United States 57511 58 Inquiry
Supplier Advantage
CLEARSYNTH LABS LTD. 58
ATK CHEMICAL COMPANY LIMITED 60
TargetMol Chemicals Inc. 58
Dideu Industries Group Limited 58
Zhejiang J&C Biological Technology Co.,Limited 58
InvivoChem 58
LEAP CHEM CO., LTD. 58
Nantong HI-FUTURE Biology Co., Ltd. 58
Wuhan Topule Biopharmaceutical Co., Ltd 58
Aladdin Scientific 58

MK8745 Spectrum

MK8745(885325-71-3)1HNMR

885325-71-3(MK8745)Related Search:

MK-8998 MK-4101 MK-3903 mk-1064 (S)-2-(4-(piperidin-3-yl)phenyl)-2H-indazole-7-carboxaMide
MK 0557 MK-0812 (Succinate) MKC9989 MKC3946 MK-5108 (VX-689)
Aurora A Inhibitor I VE 822 LDN-193189 Hesperadin MLN8054
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MK8745 6-[[4-(3-Chloro-2-fluorobenzoyl)piperazin-1-yl]methyl]-N-(thiazol-2-yl)pyridin-2-amine Methanone, (3-chloro-2-fluorophenyl)[4-[[6-(2-thiazolylamino)-2-pyridinyl]methyl]-1-piperazinyl]- (3-chloro-2-fluorophenyl)(4-((6-(thiazol-2-ylamino)pyridin-2-yl)methyl)piperazin-1-yl)methanone. MK-8745 (3-Chloro-2-fluorophenyl)(4-((6-(thiazol-2-ylamino)pyridin-2-yl)methyl)piperazin-1-yl)methanon CS-1904 MK8745 USP/EP/BP Inhibitor,inhibit,MK8745,Aurora Kinase,MK-8745,MK 8745,Apoptosis 885325-71-3 C20H19ClFN5OS API Inhibitors