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NSC5844

NSC5844 Structure
CAS No.
140926-75-6
Chemical Name:
NSC5844
Synonyms
RE640;RE 640;RE-640;NSC5844;NSC5844 (RE640);NSC 5844; NSC-5844; RE 640; RE-640; RE640;N,N'-bis(7-chloroquinolin-4-yl)ethane-1,2-diamine;1,2-Ethanediamine, N1,N2-bis(7-chloro-4-quinolinyl)-;NSC 5844,RE640,NSC5844,inhibit,Inhibitor,RE 640,Parasite,NSC-5844
CBNumber:
CB53121123
Molecular Formula:
C20H16Cl2N4
Molecular Weight:
383.27
MOL File:
140926-75-6.mol
Modify Date:
2024/7/2 8:55:11
Request For Quotation

NSC5844 Properties

Boiling point 632.6±55.0 °C(Predicted)
Density 1.431±0.06 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMF: 0.33 mg/ml; DMSO: 0.25 mg/ml; Ethanol: slightly soluble
form A crystalline solid
pka 6.61±0.50(Predicted)
color White to off-white

NSC5844 Chemical Properties,Uses,Production

Description

NSC 5844 is a bis-quinoline with diverse biological activities. It inhibits the growth of P. falciparum strains that are sensitive (D-6) and resistant (W-2) to chloroquine in vitro (IC50s = 17 and 27 nM, respectively) but lacks activity against P. berghei in vivo. NSC 5844 inhibits the growth of MDA-MB-468 and MCF-7 breast cancer cells with GI50 values of 7.35 and 14.80 μM, respectively. It also inhibits 24% of botulinum neurotoxin serotype A light chain (BoNT/A LC) metalloprotease activity at a concentration of 20 μM.

NSC5844 Preparation Products And Raw materials

Raw materials

Preparation Products

NSC5844 Suppliers

Global( 70)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
ATK CHEMICAL COMPANY LIMITED +undefined-21-51877795 China 32760 60 Inquiry
InvivoChem +1-708-310-1919 +1-13798911105 United States 6393 58 Inquiry
TargetMol Chemicals Inc. +1-781-999-5354 United States 19973 58 Inquiry
ShenZhen Trendseen Biological Technology Co.,Ltd. 13417589054 China 11681 58 Inquiry
Henan Fengda Chemical Co., Ltd +86-371-86557731 +86-13613820652 China 20361 58 Inquiry
Aladdin Scientific +1-+1(833)-552-7181 United States 57511 58 Inquiry
Wuhan Jingkang en Biomedical Technology Co., Ltd +8613720134139 China 4692 58 Inquiry
Amadis Chemical Company Limited 571-89925085 China 131980 58 Inquiry
Boao Pike 010-57798038 15652371397 CHINA 6629 58 Inquiry
Shanghai Han-Xiang Chemical Co., Ltd. +86 (21) 5027-2946, +86 13818785766 China 1039 50 Inquiry
Supplier Advantage
ATK CHEMICAL COMPANY LIMITED 60
InvivoChem 58
TargetMol Chemicals Inc. 58
ShenZhen Trendseen Biological Technology Co.,Ltd. 58
Henan Fengda Chemical Co., Ltd 58
Aladdin Scientific 58
Wuhan Jingkang en Biomedical Technology Co., Ltd 58
Amadis Chemical Company Limited 58
Boao Pike 58
Shanghai Han-Xiang Chemical Co., Ltd. 50

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NSC5844 N,N'-bis(7-chloroquinolin-4-yl)ethane-1,2-diamine 1,2-Ethanediamine, N1,N2-bis(7-chloro-4-quinolinyl)- RE-640 RE640 RE 640 NSC 5844; NSC-5844; RE 640; RE-640; RE640 NSC5844 (RE640) NSC 5844,RE640,NSC5844,inhibit,Inhibitor,RE 640,Parasite,NSC-5844 140926-75-6