Isopropyl chloroformate
- CAS No.
- 108-23-6
- Chemical Name:
- Isopropyl chloroformate
- Synonyms
- isopropyl carbonochloridate;IPCF;ISOPROPYL CHLOROCARBONATE;ISOPROPYL CHLOROMATE;Isopropyl chloroform;1-PROPYLCHLOROFORMATE;2-Methylchloroformate;Tenofovir Impurity 95;Isopropylchlorcarbonat;sopropyl chloroformate
- CBNumber:
- CB5702693
- Molecular Formula:
- C4H7ClO2
- Molecular Weight:
- 122.55
- MOL File:
- 108-23-6.mol
- Modify Date:
- 2024/8/24 19:19:26
| Boiling point | 105 °C |
|---|---|
| Density | 0.892 g/mL at 25 °C |
| vapor pressure | 27.998hPa at 20℃ |
| refractive index |
n |
| Flash point | 43 °F |
| storage temp. | 2-8°C |
| solubility | Chloroform (Sparingly), Dichloromethane (Soluble), Ethyl Acetate (Slightly), Tol |
| BRN | 506416 |
| Stability | Moisture Sensitive |
| InChIKey | IVRIRQXJSNCSPQ-UHFFFAOYSA-N |
| CAS DataBase Reference | 108-23-6(CAS DataBase Reference) |
| EPA Substance Registry System | Isopropyl chloroformate (108-23-6) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |     GHS02,GHS05,GHS06,GHS08 |
|---|---|
| Signal word | Danger |
| Hazard statements | H225-H304-H314-H317-H330-H336-H361d-H373 |
| Precautionary statements | P210-P260-P280-P284-P301+P310-P305+P351+P338 |
| Hazard Codes | F,C,T+ |
| Risk Statements | 11-34-48/20-63-65-67-43-26 |
| Safety Statements | 26-36/37/39-45-62-28-16 |
| RIDADR | UN 3286 3/PG 2 |
| WGK Germany | 2 |
| RTECS | LQ6475000 |
| F | 10-19 |
| HazardClass | 6.1(a) |
| PackingGroup | I |
| HS Code | 29159000 |
Isopropyl chloroformate price More Price(2)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | 335908 | Isopropyl chloroformate solution 1.0?M in toluene | 108-23-6 | 100ML | ₹9110.5 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 335908 | Isopropyl chloroformate solution 1.0?M in toluene | 108-23-6 | 800ML | ₹22503.6 | 2022-06-14 | Buy |
Isopropyl chloroformate Chemical Properties,Uses,Production
Chemical Properties
Isopropyl chloroformate is a colorless liquid with corrosive properties and a pungent odor. generally present as 1.0 mol/L toluene solution of isopropyl chloroformate. It is a highly flammable chemical. Isopropyl chloroformate decomposes when heated, producing toxic and corrosive fumes, including hydrogen chloride and phosgene. The chemical reacts with water to produce alcohol and hydrogen chloride. Hydrolysis would yield chloroformic acid, which is considered a strong acid.
Uses
Chemical intermediate for free-radical polymerization initiators, organic synthesis.
Production Methods
Prepared by the reaction of liquid anhydrous isopropyl alcohol with molar excess of dry, chlorine-free phosgene at low temperature.
General Description
A clear colorless volatile liquid with a pungent irritating odor. About the same density as water and insoluble in water. Floats on water Flash point 75°F. Very irritating to skin and eyes and very toxic by inhalation, ingestion and skin absorption. Used to make other chemicals.
Air & Water Reactions
Highly flammable. Gives off HCl fumes in moist air. Insoluble in water. Decomposes slowly in water forming isopropyl alcohol, HCl, and CO2.
Reactivity Profile
Isopropyl chloroformate is water reactive. A sample stored in a refrigerator exploded [Wischmeyer 1973]. Attacks many metals especially in humid atmosphere [Handling Chemicals Safely, 1980. p. 476]. May react vigorously or explosively if mixed with diisopropyl ether or other ethers in the presence of trace amounts of metal salts [J. Haz. Mat., 1981, 4, 291].
Hazard
Toxic by inhalation.
Health Hazard
Acute: highly toxic by inhalation, ingestion and skin absorption. Delayed: can produce delayed pulmonary edema (2-24 hours after exposure) similar to that produced by phosgene. Inhalation of material may cause death or permanent injury.
Fire Hazard
Extremely dangerous; Isopropyl chloroformate has exploded while stored in refrigerator. Vapor explosion hazard indoors, outdoors or in sewers. Runoff to sewer may create fire or explosion hazard. Like other chlorides, when heated to decomposition or on contact with acids or acrid fumes, they evolve highly toxic chloride fumes. Reacts violently with phosgene. Unstable, avoid phosgene
Isopropyl chloroformate Preparation Products And Raw materials
Raw materials
Preparation Products
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chevron_right| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| Paushak Limited | +91-2653007932 +91-9727736899 | Vadodara, India | 59 | 58 | Inquiry |
| LANXESS India Pvt. Ltd. | +91-8356878763 +91-8356878763 | Maharashtra, India | 190 | 58 | Inquiry |
| OCEAN TRADING CORPORATION | +91(22) 24921669 | New Delhi, India | 6211 | 58 | Inquiry |
| TCI Chemicals (India) Pvt. Ltd. | 1800 425 7889 | New Delhi, India | 6778 | 58 | Inquiry |
| Manus Aktteva Biopharma LLP | 08048250218Ext 800 | Ahmedabad, India | 655 | 58 | Inquiry |
| BrmoChem | +91 22 40013000 | Mumbai, India | 70 | 58 | Inquiry |
| Paushak Limited | 09727736899 | Vadodara, India | 22 | 58 | Inquiry |
| Brom-Chem | +91 22 40013014 | Mumbai, India | 62 | 58 | Inquiry |
| LANXESS India Pvt. Ltd. | +91-22-2587 1000 | Maharashtra, India | 131 | 58 | Inquiry |
| Atul Limited - PP Site | +91 2632 233261 | Gujarat, India | 23 | 58 | Inquiry |
| Supplier | Advantage |
|---|---|
| Paushak Limited | 58 |
| LANXESS India Pvt. Ltd. | 58 |
| OCEAN TRADING CORPORATION | 58 |
| TCI Chemicals (India) Pvt. Ltd. | 58 |
| Manus Aktteva Biopharma LLP | 58 |
| BrmoChem | 58 |
| Paushak Limited | 58 |
| Brom-Chem | 58 |
| LANXESS India Pvt. Ltd. | 58 |
| Atul Limited - PP Site | 58 |
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