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Ketanserin

Ketanserin Structure
CAS No.
74050-98-9
Chemical Name:
Ketanserin
Synonyms
RHS;Ket;p73L;p73H;OFC8;EEC3;SHFM4;p53CP;TP53L;TP73L
CBNumber:
CB5704758
Molecular Formula:
C22H22FN3O3
Molecular Weight:
395.43
MOL File:
74050-98-9.mol
Modify Date:
2023/9/15 15:02:29

Ketanserin Properties

Melting point 227-235°C
Density 1.280±0.06 g/cm3(Predicted)
storage temp. Sealed in dry,2-8°C
solubility DMF: 10 mg/mL, clear, colorless
form Solid
pka 7.5(at 25℃)
color White to Off-White
Merck 14,5296
CAS DataBase Reference 74050-98-9(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P501-P270-P264-P301+P312+P330
WGK Germany  3
RTECS  VA1411190
HS Code  29339900
NFPA 704
0
2 0

Ketanserin price More Price(2)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TCI Chemicals (India) K0051 Ketanserin 74050-98-9 200MG ₹5400 2022-05-26 Buy
TCI Chemicals (India) K0051 Ketanserin 74050-98-9 1G ₹14600 2022-05-26 Buy
Product number Packaging Price Buy
K0051 200MG ₹5400 Buy
K0051 1G ₹14600 Buy

Ketanserin Chemical Properties,Uses,Production

Description

Ketanserin is an antihypertensive agent with antagonist properties at both the serotonin-S2 and α1-adrenergic receptors. Its mechanism of action, while still controversial, may involve interactions at both of these loci.

Chemical Properties

Off-White Solid

Uses

An antihypertensive, with affinity for multiple GPCR receptors.

Definition

ChEBI: A member of the class of quinazolines that is quinazoline-2,4(1H,3H)-dione which is substituted at position 3 by a 2-[4-(p-fluorobenzoyl)piperidin-1-yl]ethyl group.

Purification Methods

It has been purified by recrystallisation from 4-methyl-3-pentanone [Peeters et al. Cryst Structure Commun 11 375 1982, Kacprowicz et al. J Chromatogr 272 417 1983, Davies et al. J Chromatogr 275 232 1983]. It is an antihypertensive.

Ketanserin Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 221)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
A.J Chemicals 91-9810153283 New Delhi, India 6124 58 Inquiry
TCI Chemicals (India) Pvt. Ltd. 1800 425 7889 New Delhi, India 6778 58 Inquiry
Pharmaffiliates Analytics and Synthetics P. Ltd +91-172-5066494 Haryana, India 6773 58 Inquiry
Clearsynth Labs 91-22-45045900 Maharashtra, India 3889 58 Inquiry
Pharma Affiliates 172-5066494 Haryana, India 6761 58 Inquiry
Hebei Yanxi Chemical Co., Ltd. +86-17531190177; +8617531190177 China 6011 58 Inquiry
Henan Tianfu Chemical Co.,Ltd. +86-0371-55170693 +86-19937530512 China 21678 55 Inquiry
ATK CHEMICAL COMPANY LIMITED +undefined-21-51877795 China 32715 60 Inquiry
career henan chemical co +86-0371-86658258 15093356674; China 29902 58 Inquiry

Ketanserin Spectrum

B(p51A) B(p51B) EEC3 OFC8 p53CP p63, GST tagged human p73H p73L RHS SHFM4 TP53CP TP53L TP73L 3-[2-[4-(4-fluorobenzoyl)-1-piperidinyl]ethyl]-2,4[1h,3h]-quinazolinedione KETANSERIN 3-(2-(4-(4-fluorobenzoyl)piperidin-1-yl)ethyl)quinazoline-2,4(1H,3H)-dione 3-[2-[4-(4-Fluorobenzoyl)-1-piperidinyl]ethyl]-2,4-(IH,3H)-quinazolinedione Ketanserin (Vulketan Gel)| Ketanserin(R 41 468) Ket Ketensin Perketan R-49945 Serefrex Serepress Sufrexal Taseron 2,4(1H,3H)-Quinazolinedione, 3-[2-[4-(4-fluorobenzoyl)-1-piperidinyl]ethyl]- 3-[2-[4-(4-Fluorobenzoyl)piperidin-1-yl]ethyl]-1H-quinazoline-2,4-dione 3-[2-[4-(4-Fluorobenzoyl)piperidin-1-yl]ethyl]-2,4(1H,3H)-quinazolinedione 3-[2-[4-(4-Fluorobenzoyl)piperidino]ethyl]-2,4(1H,3H)-quinazolinedione Ketanserine Ketanserin, 99%, a specific 5-HT2A serotonin receptor antagonist Ketanserin> Ketanserinum Ketanserin USP/EP/BP Ketanserine Base 3-{2-[4-(4-fluorobenzoyl)piperidin-1-yl]ethyl}-1,2,3, 4-tetrahydroquinazoline-2,4-dione TIANFU CHEM----Ketanserin Ketanserin,3-[2-[4-(4-Fluorobenzoyl)-1-piperidinyl]ethyl]-2,4[1H,3H]-quinazolinedione 3-[2-[4-(4-Fluorobenzoyl)-1-piperidyl]ethyl]quinazoline-2,4(1H,3H)-dione 74050-98-9 C22H22FN3O3 Intermediates & Fine Chemicals Pharmaceuticals Other APIs ketone