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ChemicalBook > Product Catalog >Chemical Reagents >Organic reagents >Fatty alcohols >2,2,2-Trifluoroethanol

2,2,2-Trifluoroethanol

2,2,2-Trifluoroethanol Structure
CAS No.
75-89-8
Chemical Name:
2,2,2-Trifluoroethanol
Synonyms
TFE;CF3CH2OH;TRIFLUOROETHANOL;2,2,2-TRIFLUROETHANOL;TFETOH;2,2,2-Trifluoroethan;2,2,2-Trifluorethanol;2,2,2-Trifluoroethyl alcohol;TFEA;TFE/TFEA
CBNumber:
CB5736665
Molecular Formula:
C2H3F3O
Molecular Weight:
100.04
MOL File:
75-89-8.mol
MSDS File:
SDS
Modify Date:
2023/11/28 16:31:44
Request For Quotation

2,2,2-Trifluoroethanol Properties

Melting point −44 °C(lit.)
Boiling point 77-80 °C(lit.)
Density 1.391 g/mL at 20 °C
vapor density 3.5 (vs air)
vapor pressure 70 mm Hg ( 25 °C)
refractive index n20/D 1.3(lit.)
Flash point 85 °F
storage temp. Store below +30°C.
solubility soluble in Chloroform, Methanol
form Liquid
pka 12.4(at 25℃)
color Clear colorless
Specific Gravity 1.373
Odor Alcoholic odour
PH Range 5-7 (10% aq soln)
explosive limit 8.4-28.8%(V)
Water Solubility Miscible with water, ethers, ketones, alcohols and chloroform.
λmax λ: 260 nm Amax: ≤0.03
λ: 280 nm Amax: ≤0.02
Merck 14,9682
BRN 1733203
Dielectric constant 8.5500000000000007
Stability Stable. Flammable - note wide explosion limits. Moisture sensitive. Incompatible with strong oxidizing agents, strong acids, sodium, potassium.
InChIKey RHQDFWAXVIIEBN-UHFFFAOYSA-N
CAS DataBase Reference 75-89-8(CAS DataBase Reference)
NIST Chemistry Reference Ethanol, 2,2,2-trifluoro-(75-89-8)
EPA Substance Registry System 2,2,2-Trifluoroethanol (75-89-8)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS02,GHS05,GHS06,GHS08
Signal word  Danger
Hazard statements  H226-H301+H331-H318-H360F-H373
Precautionary statements  P201-P210-P280-P301+P310-P304+P340+P311-P305+P351+P338
Hazard Codes  Xn,T,F
Risk Statements  10-20/21/22-37/38-41-62-38-36/37/38
Safety Statements  26-36-39-45-36/37/39-16
RIDADR  UN 1986 3/PG 3
WGK Germany  1
RTECS  KM5250000
Autoignition Temperature ~896 °F
Hazard Note  Flammable/Toxic
TSCA  Yes
HazardClass  3
PackingGroup  III
HS Code  29055910
Toxicity LD50 orally in Rabbit: 240 mg/kg LD50 dermal Rat 1680 mg/kg
NFPA 704
2
3 0

2,2,2-Trifluoroethanol price More Price(8)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) SAB2501711 Anti-TFE3 (N-terminal) antibody produced in goat affinity isolated antibody, buffered aqueous solution 75-89-8 100μG ₹53135.7 2022-06-14 Buy
TCI Chemicals (India) T0435 2,2,2-Trifluoroethanol min. 99.0 % 75-89-8 25G ₹2400 2022-05-26 Buy
TCI Chemicals (India) T0435 2,2,2-Trifluoroethanol min. 99.0 % 75-89-8 100G ₹5000 2022-05-26 Buy
TCI Chemicals (India) T0435 2,2,2-Trifluoroethanol min. 99.0 % 75-89-8 500G ₹14600 2022-05-26 Buy
ottokemi T 2155 2,2,2-Trifluoroethanol 99% 75-89-8 100mL ₹1305 2022-05-26 Buy
Product number Packaging Price Buy
SAB2501711 100μG ₹53135.7 Buy
T0435 25G ₹2400 Buy
T0435 100G ₹5000 Buy
T0435 500G ₹14600 Buy
T 2155 100mL ₹1305 Buy

2,2,2-Trifluoroethanol Chemical Properties,Uses,Production

Chemical Properties

Colorless liquid

Uses

2,2,2-Trifluoroethanol (Trifluoroethyl alcohol, TFE) is used to study the conformational states of proteins and the folding refolding processes of proteins.

Safety Profile

Poison by ingestion, intravenous, and intraperitoneal routes. Moderately toxic by inhalation and skin contact. Experimental reproductive effects. A severe skin and eye irritant. When heated to decomposition it emits toxic fumes of F-.

Purification Methods

Dry it with CaSO4 and a little NaHCO3 (to remove traces of acid) and distil it. Highly TOXIC vapour. [Beilstein 1 IV 1370.]

2,2,2-Trifluoroethanol Preparation Products And Raw materials

Raw materials

2,2,2-Trifluorodiazoethane Benzene, [(2,2,2-trifluoroethoxy)methyl]- 4-(prop-1-en-2-yl)phenyl acetate

Preparation Products

6-(2,2,2-TRIFLUOROETHOXY)NICOTINIC ACID 3,3,3-Trifluoropropionic acid 2-(2,2,2-TRIFLUOROETHOXY)PYRIDINE-3-CARBOXYLIC ACID TRIFLUOROACETALDEHYDE HYDRATE TRIS(2,2,2-TRIFLUOROETHYL)PHOSPHATE
Isoflurane 2-Chloromethyl-3-methyl-4-(2,2,2-trifluoroethoxy)pyridine hydrochloride 1,1,1,2-Tetrafluoroethane 2-CHLORO-1,1,1-TRIFLUOROETHANE pent-1-en-3-yne
1,3,2-Dioxaphospholane, 2-(2,2,2-trifluoroethoxy)-, 2-oxide 2-Hydroxy-1,3,2-dioxaphospholane 2-oxide 2,6-BIS(2,2,2-TRIFLUOROETHOXY)BENZONITRILE 2,2,2-TRIFLUOROETHYL CHLOROFORMATE 1,1,2,3,3,3-HEXAFLUOROPROPYL 2,2,2-TRIFLUOROETHYL ETHER
Potassium trifluoroacetate
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2,2,2-Trifluoroethanol Suppliers

Global( 524)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
ULTIMA CHEMICALS +91 7208029458 Mumbai, India 95 58 Inquiry
JSK Chemicals +919879767970 Gujarat, India 3756 58 Inquiry
SL Drugs and Pharmaceuticals Pvt. Ltd. +91 (40) 6661-1133 New Delhi, India 2688 50 Inquiry
Trignokem International +91 (40) 2717-0709 New Delhi, India 380 50 Inquiry
KKyemistry (India) Pvt. Ltd. +91 (40) 2351-0950 New Delhi, India 197 50 Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
A.J Chemicals 91-9810153283 New Delhi, India 6124 58 Inquiry
Ashchemie India 09821323153 Maharashtra, India 30 58 Inquiry
Ozone Ingredients 08048250471Ext 902 Gujarat, India 17 58 Inquiry
GVSK Pharma Private Limited 07942560916 Hyderabad, India 33 58 Inquiry
Supplier Advantage
ULTIMA CHEMICALS 58
JSK Chemicals 58
SL Drugs and Pharmaceuticals Pvt. Ltd. 50
Trignokem International 50
KKyemistry (India) Pvt. Ltd. 50
CLEARSYNTH LABS LTD. 58
A.J Chemicals 58
Ashchemie India 58
Ozone Ingredients 58
GVSK Pharma Private Limited 58

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Trifluoro Ethanol(L) 2,2,2-Trifluoroethanol,Trifluoroethyl alcohol 2,2,2-Trifluoroethanol, reagent grade 2,2,2-Trifluoroethan-1-ol 99% 2-Hydroxy-1,1,1-trifluoroethane, (Trifluoromethyl)methanol 2,2,2-TRIFLUOROETHANOL-D3, HIGH ENRICHMENT 1,2,2-trifluoroethan-1-ol 2,2,2-Trifluoroethanol (TFE) ,2,2-Trifluoroethyl alcohol 2(3H)-Benzofuranone, 5-hydroxy- 5-Hydroxy-3H-1-benzofuran-2-one b,b,b-Trifluoroethyl alcohol 2,2,2-TRIFLUOROETHANOL, 99.8%, EXTRA PURE 2,2,2-Trifluoroethanol, extra pure 2,2,2-Trifluoroethanol, extra pure, 99.8% 100ML 2,2,2-Trifluoroethanol, extra pure, 99.8% 25ML 2,2,2-Trifluoroethanol, extra pure, 99.8% 500ML 2,2,2-Trifluroroethanol 2,2,2-Trifluoroethanol (TFEA) Three fluorine ethanol 2,2,2-Trifluor Transcription factor for IgH enhancer 2,2,2-Trifluoroethanol ReagentPlus(R), >=99% 1,1H-perfluoroethanol 2,2,2-Thifluoroethanol 2,2,2-trifluoro-ethano TRIFLUOROETHYL ALCOHOL VITAS-BB TBB000650 BETA,BETA,BETA-TRIFLUOROETHANOL BETA,BETA,BETA-TRIFLUOROETHYL ALCOHOL 2,2,2-Trifluoroethanol,99% 2,2,2-trifluoroethanol, nmr grade PERFLUORO-1,1-DIHYDROETHANOL 2,2,2-trifluoroethylalcohol beta,beta,beta-trifluoroethanol2,2,2-trifluoroethylalcohol,tfe Ethanol,2,2,2-trifluoro- Fluorinol 85 Trifluoroethylalchohol trifluroroethylalchohol TFE/TFEA 2，2，2-Trifiuoroethyl alcohol 2,2,2-TRIFLUOROETHANOL 1H,1H-TRIFLUOROETHANOL Trifluoroethanol1 Trifluoroethanol2 2,2,2-Tridluoroethanol 2,2,2,-Trifluoroehtanol 2,2,2-TRIFLUOROETHANOL, CALIB. STANDARD FOR NMR-SPECTROSCOPY 2,2,2-TRIFLUOROETHANOL, 99.5+%, NMR GRAD E 2,2,2-TRIFLUOROETHANOL, REAGENTPLUS, >=99% 2 2 2-TRIFLUOROETHANOL 99.5+% & 2,2,2-Trifluoroethanol, extra pure, 99.8% 2,2,2-TRIFLUOROETHANOL: 99.95%, NMR GRADE 2,2,2-TRIFLUOROETHANOL, NMR GRADE: 99.5% 2,2,2-TRIFLUOROETHANOL, 99%2,2,2-TRIFLUOROETHANOL, 99%2,2,2-TRIFLUOROETHANOL, 99% 2,2,2-Trifluoroethanol (TFEA), NMR grade 2,2,2-TrifL uoroethanoL