Chinese english Japanese Germany Korea
ChemicalBook > Product Catalog >Chemical Reagents >Organic reagents >Esters >Ethyl compound >Ethyl trifluoroacetate

Ethyl trifluoroacetate

Ethyl trifluoroacetate Structure
CAS No.
383-63-1
Chemical Name:
Ethyl trifluoroacetate
Synonyms
ETHYL 2,2,2-TRIFLUOROACETATE;ETFA;TFAET;TRIFLUOROACETIC ACID ETHYL ESTER;CF3COOC2H5;RARECHEM AL BI 0416;2,2,2-Trifluoroacetic acid ethyl ester;cb1020;fd06h11;wu:fd06h11
CBNumber:
CB6349488
Molecular Formula:
C4H5F3O2
Molecular Weight:
142.08
MOL File:
383-63-1.mol
MSDS File:
SDS
Modify Date:
2024/8/13 17:19:14
Request For Quotation

Ethyl trifluoroacetate Properties

Melting point -78 °C
Boiling point 60-62 °C(lit.)
Density 1.194 g/mL at 25 °C(lit.)
vapor pressure 18.5kPa at 20℃
refractive index n20/D 1.307(lit.)
Flash point 30 °F
storage temp. 2-8°C
solubility 4g/l
pka 0.43[at 20 ℃]
form Liquid
Specific Gravity 1.194
color Clear
PH 4 (4g/l, H2O, 20℃)
Water Solubility HYDROLYSIS
Sensitive Moisture Sensitive
BRN 1761411
Stability Hygroscopic, Moisture Sensitive, Volatile
InChIKey STSCVKRWJPWALQ-UHFFFAOYSA-N
LogP 0.79-1.032 at 25℃
CAS DataBase Reference 383-63-1(CAS DataBase Reference)
NIST Chemistry Reference Acetic acid, trifluoro-, ethyl ester(383-63-1)
EPA Substance Registry System Ethyl trifluoroacetate (383-63-1)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS02,GHS05,GHS07
Signal word  Danger
Hazard statements  H225-H302-H315-H318-H335
Precautionary statements  P210-P261-P280-P305+P351+P338
Hazard Codes  F,Xn,C
Risk Statements  11-22-37/38-41-34
Safety Statements  9-16-26-36/39-45-36/37/39
RIDADR  UN 1993 3/PG 2
WGK Germany  1
Hazard Note  Flammable/Corrosive
TSCA  T
HazardClass  3
PackingGroup  II
HS Code  29159080
NFPA 704
3
2 0

Ethyl trifluoroacetate price More Price(7)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) E50000 Ethyl trifluoroacetate 99% 383-63-1 25G ₹1948.5 2022-06-14 Buy
Sigma-Aldrich(India) E50000 Ethyl trifluoroacetate 99% 383-63-1 100G ₹6191.9 2022-06-14 Buy
TCI Chemicals (India) T0432 Ethyl Trifluoroacetate min. 99.0 % 383-63-1 25G ₹2900 2022-05-26 Buy
TCI Chemicals (India) T0432 Ethyl Trifluoroacetate min. 99.0 % 383-63-1 100G ₹5500 2022-05-26 Buy
TCI Chemicals (India) T0432 Ethyl Trifluoroacetate min. 99.0 % 383-63-1 500G ₹16000 2022-05-26 Buy
Product number Packaging Price Buy
E50000 25G ₹1948.5 Buy
E50000 100G ₹6191.9 Buy
T0432 25G ₹2900 Buy
T0432 100G ₹5500 Buy
T0432 500G ₹16000 Buy

Ethyl trifluoroacetate Chemical Properties,Uses,Production

Chemical Properties

Colorless to yellow liquid

Uses

Ethyl Trifluoroacetate is an intermediate used in the synthesis of various pharmaceutically active molecules and agricultural products. Ethyl Trifluoroacetate is also useful for the preparation of tri fluoroacylated compounds.

Preparation

Trifluoroacetic acid and ethanol were used as starting materials with strong-acid cation exchange resin as catalysts at 40 ~ 50 she℃. Add ethanol drop and temperature rising reflux divides the mixture of water and ethanol. After that, collect the mix of thick product ethanol and Ethyl trifluoroacetate. The crude product collected is added a small amount of water, and layering can obtain a content of more than 99.5%. The qualified product Ethyl trifluoroacetate, whose moisture is less than 0.1%, yields more than 95%.

Purification Methods

Fractionate it through a long Vigreux column (p 11). IR has max at 1800 (CO2) and 1000 (OCO) cm-1 [Fuson et al. J Chem Phys 20 1627 1952, Bergman J Org Chem 23 476 1958]. [Beilstein 2 IV 463.]

Ethyl trifluoroacetate Preparation Products And Raw materials

Raw materials

Trifluoroacetic acid Ethyl trifluoromethanesulfonate

Preparation Products

2-[1-METHYL-5-(TRIFLUOROMETHYL)PYRAZOL-3-YL]-THIOPHENE-5-CARBOXALDEHYDE EUROPIUM D-3-TRIFLUOROACETYLCAMPHORATE 8-CHLORO-2-(TRIFLUOROMETHYL)QUINOLINE-4-CARBONITRILE 3-TRIFLUOROACETYL-D-CAMPHOR 6,7-DIMETHOXY-3-METHYL-1,2,3,4-TETRAHYDROISOQUINOLINE HYDROCHLORIDE
2-AMINO-4-PHENYL-6-(TRIFLUOROMETHYL)PYRIMIDINE 4,4,4-Trifluoro-1-phenyl-1,3-butanedione 2-AMINO-6-T-BUTYL-4-(TRIFLUOROMETHYL)PYRIMIDINE METHYL5,5,5-TRIFLUORO-4-OXOPENTANOATE 1,1,1-Trifluoro-2-hexanone
Efavirenz 4-(TRIFLUOROMETHYL)-ALPHA,ALPHA,ALPHA-TRIFLUOROACETOPHENONE HEXAFLUOROACETYLACETONE BENZALDEHYDE DIETHYL ACETAL 1,1,1-TRIFLUORO-5,5-DIMETHYL-2,4-HEXANEDIONE
2-(TRIFLUOROMETHYL)PYRIMIDINE-4,6-DIOL 3'-METHOXY-2,2,2-TRIFLUOROACETOPHENONE 3-PHENYL-1,1,1-TRIFLUOROPROPAN-2-ONE 1-(2-AMINO-5-CHLOROPHENYL)-2,2,2-TRIFLUOROETHANONE
chevron_left

1of4

chevron_right

Ethyl trifluoroacetate Suppliers

Global( 544)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
JSK Chemicals +919879767970 Gujarat, India 3756 58 Inquiry
SRF Limited +91-9810617574 +91-9650533660 Haryana, India 40 58 Inquiry
ALS INDIA LIFE SCIENCES +91-8977036379 +91-8977036379 Hyderabad, India 1879 58 Inquiry
Survival Technologies Pvt Ltd +91 (22) 4212-8221 New Delhi, India 290 50 Inquiry
A.J Chemicals 91-9810153283 New Delhi, India 6124 58 Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
TCI Chemicals (India) Pvt. Ltd. 1800 425 7889 New Delhi, India 6778 58 Inquiry
Otto Chemie Pvt. Ltd. +91 9820041841 Mumbai, India 5873 58 Inquiry
Alfa Aesar 1 800 209 7001 Maharashtra, India 6913 58 Inquiry
LOBA CHEMIE PVT.LTD. 91-22-6663 6699 Mumbai, India 3077 58 Inquiry
Supplier Advantage
JSK Chemicals 58
SRF Limited 58
ALS INDIA LIFE SCIENCES 58
Survival Technologies Pvt Ltd 50
A.J Chemicals 58
CLEARSYNTH LABS LTD. 58
TCI Chemicals (India) Pvt. Ltd. 58
Otto Chemie Pvt. Ltd. 58
Alfa Aesar 58
LOBA CHEMIE PVT.LTD. 58

Ethyl trifluoroacetate Spectrum

Ethyl trifluoroacetate(383-63-1)MSEthyl trifluoroacetate(383-63-1)1HNMREthyl trifluoroacetate(383-63-1)13CNMREthyl trifluoroacetate(383-63-1)IR1Ethyl trifluoroacetate(383-63-1)Raman

383-63-1(Ethyl trifluoroacetate)Related Search:

Ethyl fluoroacetate Trifluoroacetic anhydride Ethyl cellulose Ethylbenzene Trifluoroacetic acid
CHLOROETHANE Ethylparaben ETHYL CHLOROFLUOROACETATE Ethanol Ethyl acetate
Ethyl difluoroacetate 2,2,2-Trifluoroethyl acrylate Ethyl acrylate Ethyl formate 2,4,6-TRIMETHOXY-1,3,5-TRIAZINE
TRICAPRIN Triethylene glycol diacetate TRIMETHYLSILYL ISOCYANATE
chevron_left

1of4

chevron_right
ETHYL TRIFLUOROACETATE TIMTEC-BB SBB008466 Threetrifluoroacetic acid ethyl ester cb1020 fd06h11 wu:fd06h11 aceticacid,trifluoro-,ethylester Ethyl ester of Trifluoroacetic acid Ethyl trifluoroethanoate ethylperfluoroacetate Trifluoressigsαureethylester trifluoro-aceticaciethylester VITAS-BB TBB000648 3,4,5-Trimethoxybenzenesulfonic Acid Sodium ETHYL TRIFLUOROACETATE 98% (GC) Ethyl trifluoroacetate,99% Ethyl trifluoroacetate 99% 2,2,2-TRIFLOUROETHYL ACETATE (TFAET) Ethyltrifluoracetat trifluoroacetatic acid ethyl ester Ethyl trifluoroacetate, 98+% Ethyl trifluoroaceta Trifluoroacetic acid ethyl Ethyl 4-trifluoroacetate Ethyl trifluoroacetate, 99% 100ML Ethyl trifluoroacetate, 99% 25ML Ethyl trifluoroacetate or Propyl ester Ethyltrifuoroacetate Ethyltrifluoroacetate(ETFA) Ethyl Trifluoroacetate > ETHYL TRIFLUOROACETATE For Synthesis RARECHEM AL BI 0416 ETHYL 2,2,2-TRIFLUOROACETATE TRIFLUOROACETIC ACID ETHYL ESTER CF3COOC2H5 TFAET ETFA 2,2,2-Trifluoroacetic acid ethyl ester Sitagliptin Impurity 76 Ethyl trifluoroacetate（TFAE） 383-63-1 CF3CO2C2H5 F3CCOOC2H5 C4H5F3O2 CF3CO2CH2CH3 Building Blocks Carbonyl Compounds C2 to C5 Organic Building Blocks Esters Fluorinated Building Blocks Fluorinating Reagents & Building Blocks for Fluorinated Biochemical Compounds organofluorine compounds Building Blocks C2 to C5 Carbonyl Compounds Chemical Synthesis Esters