11-alpha-Hydroxycarvenone

11-alpha-Hydroxycarvenone Structure
CAS No.
192569-17-8
Chemical Name:
11-alpha-Hydroxycarvenone
Synonyms
11α-Hydroxy Canrenone;11-alpha-Hydroxycar;11A-hydroxykanolone;11-HYDROXY-CANRENONE;11α-Hydroxycarvenone;11α-Hydroxy canrenon;Eplerenone Impurity 24;11α-hydroxyl canrenone;11-alpha-Hydroxycarvene;11Alpha-HydroxyCanrenone
CBNumber:
CB5837368
Molecular Formula:
C22H28O4
Molecular Weight:
356.46
MOL File:
192569-17-8.mol
Modify Date:
2024/3/22 17:12:53

11-alpha-Hydroxycarvenone Properties

Melting point 232-234°C
Boiling point 584.7±50.0 °C(Predicted)
Density 1.25
storage temp. -20°C Freezer
solubility Chloroform (Slightly), Methanol (Slightly)
form Solid
pka 14.55±0.60(Predicted)
color Pale Yellow to Brown
InChIKey RJTDWMKVQUPGSY-IPRJTMRINA-N
SMILES C[C@]12C[C@@H](O)[C@]3([H])[C@]4(CCC(=O)C=C4C=C[C@@]3([H])[C@]1([H])CC[C@]12CCC(=O)O1)C |&1:1,3,5,7,16,18,22,r|
CAS DataBase Reference 192569-17-8(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS08,GHS09
Signal word  Warning
Hazard statements  H351-H411
Precautionary statements  P201-P202-P281-P308+P313-P405-P501

11-alpha-Hydroxycarvenone Chemical Properties,Uses,Production

Chemical Properties

Yellow Crystalline Solid

Uses

11α-Hydroxy Canrenone is the key intermediate in the synthesis of Eplerenone, a cardiovascular drug. Canrenone was biotransformed into 11α-Hydroxycanrenone by Aspergillus ochraceus SIT34205.

11-alpha-Hydroxycarvenone Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 208)Suppliers
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Manus Aktteva +91 (79) 6512-3395 New Delhi, India 581 34 Inquiry
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Hebei Yanxi Chemical Co., Ltd. +86-17531190177; +8617531190177 China 6011 58 Inquiry
11-alpha-Hydroxycarvenone (11a,17a)-11,17-dihydroxy-3-oxo-pregna-4,6-diene-21-carboxylic acid 11-HYDROXY-CANRENONE 11Alpha-HydroxyCanrenone 3-(3-OXO-11A,17SS-DIHYDROXY-4,6-DIENE-PREGNA-17A-YL)PROPANOIC ACID LACTONE 3-(3-oxo-11a,17-dihydroxy-4,6-diene-pregna-17a-yl)propanoicacidlactone 11-ALPHA-HYDROXY-CARNRENONE Pregna-4,6-diene-21-carboxylic acid, 11,17-dihydroxy-3-oxo-, γ-lactone, (11α,17α)- (11α,17α)-11,17-Dihydroxy-3-oxopregna-4,6-diene-21-carboxylic Acid Eplerenone IMpurity - 11-alpha-Hydroxy Canrenone 11-alpha-Hydroxycar Eplerenone Intermediates Eplerenone intermediate 11a-Hydroxycanrenone 11α-Hydroxycarvenone 11-alpha-Hydroxycarvene Eplerenone Impurity 24 Eplerenone Canrenone Imp 11α-hydroxyl canrenone Eplerenone 11-alpha-Hydroxy Canrenone Impurity 11α-Hydroxycanrenone(A0) 11-ALPHA-HYDROXYCARVENONE 192569-17-8 (8S,9S,10R,11R,13S,14S,17R)-11-hydroxy-10,13-dimethylspiro[2,8,9,11,12,14,15,16-octahydro-1H-cyclopenta[a]phenanthrene-17,5'-oxolane]-2',3-dione 11α-Hydroxy canrenon 11α-Hydroxy Canrenone 11α-Hydroxycanrenone(A0) 11A-hydroxykanolone 192569-17-8 Intermediates & Fine Chemicals Pharmaceuticals Steroids 192569-17-8