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Canrenone

Canrenone Structure
CAS No.
976-71-6
Chemical Name:
Canrenone
Synonyms
CANRENONE-D4;sc9376;11614r.p;RP-11614;CANRENONE;phanurane;ALDADIENE;kanlitong;NSC 261713;Canrenone CRS
CBNumber:
CB0147626
Molecular Formula:
C22H28O3
Molecular Weight:
340.46
MOL File:
976-71-6.mol
MSDS File:
SDS
Modify Date:
2024/3/22 17:12:53

Canrenone Properties

Melting point 158-1600C
alpha D +24.5° (chloroform)
Boiling point 416.25°C (rough estimate)
Density 1.1236 (rough estimate)
refractive index 1.5000 (estimate)
storage temp. room temp
solubility DMSO: soluble20mg/mL, clear
form powder
color white to beige
optical activity [α]/D +17 to +24°, c = 1 in chloroform-d
Water Solubility 272.4ug/L(25 ºC)
InChI InChI=1/C22H28O3/c1-20-9-5-15(23)13-14(20)3-4-16-17(20)6-10-21(2)18(16)7-11-22(21)12-8-19(24)25-22/h3-4,13,16-18H,5-12H2,1-2H3/t16-,17+,18+,20+,21+,22-/s3
InChIKey UJVLDDZCTMKXJK-MUWITHSMNA-N
SMILES [C@@]12(CCC(=O)O1)CC[C@@]1([H])[C@]3([H])C=CC4=CC(=O)CC[C@]4(C)[C@@]3([H])CC[C@]21C |&1:0,8,10,20,22,26,r|
LogP 2.54 at 25℃
CAS DataBase Reference 976-71-6
NIST Chemistry Reference Canrenone(976-71-6)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS08,GHS09
Signal word  Warning
Hazard statements  H351-H411
Precautionary statements  P280
Hazard Codes  Xn,N
Risk Statements  40-51/53
Safety Statements  36/37-61
RIDADR  UN 3077 9 / PGIII
WGK Germany  3
HS Code  29329990

Canrenone price More Price(2)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) SML1497 Canrenone ≥97% (HPLC) 976-71-6 50MG ₹7978.03 2022-06-14 Buy
Sigma-Aldrich(India) PHR2887 Spironolactone Related Compound A pharmaceutical secondary standard, certified reference material 976-71-6 150MG ₹30970.33 2022-06-14 Buy
Product number Packaging Price Buy
SML1497 50MG ₹7978.03 Buy
PHR2887 150MG ₹30970.33 Buy

Canrenone Chemical Properties,Uses,Production

Chemical Properties

Pale yellow to pale Green Solid

Uses

Aldosterone antagonist. Diuretic

World Health Organization (WHO)

Canrenone, which has aldosterone antagonist activity, is a major metabolite of spironolactone and the major metabolite of potassium canrenoate. See WHO comments for potassium canrenoate and spironolactone.

Biological Activity

Mineralocorticoid receptor antagonist. Active metabolite of spironolactone ((7a,17a)-7-(Acetylthio)-17-hydroxy-3-oxopregn-4-ene-21-carboxylic acid g-lactone ).

Canrenone Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 262)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
Varanous Labs Pvt Ltd +91-7036248882 +91-7036248882 Hyderabad, India 1541 58 Inquiry
A.J Chemicals 91-9810153283 New Delhi, India 6124 58 Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
Pharmaffiliates Analytics and Synthetics P. Ltd +91-172-5066494 Haryana, India 6773 58 Inquiry
SynZeal Research Pvt Ltd +1 226-802-2078 Gujarat, India 6522 58 Inquiry
Clearsynth Labs 91-22-45045900 Maharashtra, India 3889 58 Inquiry
Shagun Pharmaceuticals 91-731-2575029 Madhya Pradesh, India 193 58 Inquiry
Pharma Affiliates 172-5066494 Haryana, India 6761 58 Inquiry
Hebei Kangcang new material Technology Co., LTD +8615713292910 China 341 58 Inquiry
Hebei Yanxi Chemical Co., Ltd. +86-17531190177; +8617531190177 China 6010 58 Inquiry

Canrenone Spectrum

phanurane pregna-4,6-diene-21-carboxylicacid,17-hydroxy-3-oxo-,gamma-lactone,(17-alph sc9376 spirolactonesc14266 CANRENOIC ACID GAMMA LACTONE CANRENONE 4,6-ANDROSTADIEN[(17(B-1')-SPIRO-5')]-PERHYDROFURAN-2,3-DIONE 4,6-ANDROSTEN-17-ALPHA-YL-PROPIONIOACID-R-LACTONE PREGNA-4,6-DIENE-17-BETA-0L-3-ONE-21-CARBOXYLIC ACID-GAMMA LACTONE 11614r.p 17-(2-Carboxyethyl)17-hydroxy-3-oxoandrosta-4,6-dienelactone 17-(2-Carboxyethyl)17-hydroxyandrosta-4,6-dien-3-onelactone 17-hydroxy-3-oxo-,gamma-lactone,(17-alpha)-pregna-6-diene-21-carboxylicacid 17-Hydroxy-3-oxo-17-pregna-4,6-diene-21-carboxylicacid-lactone ALDADIENE 17-hydroxy-3-oxo-17a-pregna-4,6-diene-21-carboxylic acid gamma-lactone CANRENONE[SPIRONOLACTONE INTERMEDIATE] Canrenone98.5%Min 17a-(2-Carboxyethyl-17b-hydroxyandrosta-4,6-dien-3-one Lactone (7a)-17-Hydroxy-3-oxo-pregna-4,6-diene-21-carboxylic Acid g-Lactone ((7 )-17-Hydroxy-3-oxo-pregna-4,6-diene-21-carboxylic Acid -Lactone) (7a)-17-Hydroxy-3-oxo-pregna-4,6-diene-21-carboxylic Acid -Lactone 17a-2-Carboxyethyl-17-hydroxyandrosta-4,6-dien-3-one Lactone Journal of risperidone Canrenone, >=97% (17R)-17-Hydroxy-3-oxopregna-4,6-diene-21-carboxylic acid γ-lactone (17R)-3-Oxo-17-hydroxypregna-4,6-diene-21-carboxylic acid γ-lactone (17α)-17-Hydroxy-3-oxopregna-4,6-diene-21-carboxylicacidγ-lactone Spironolactone Related Compound A (100 mg) (Canrenone (3-Oxo-17-alpha-pregna-4,6-diene-21, 17-carbolactone)) (AS) Eplerenone IMpurity - Canrenone (8R,9S,10R,13S,14S,17R)-10,13-dimethylspiro[2,8,9,11,12,14,15,16-octahydro-1H-cyclopenta[a]phenanthrene-17,5'-oxolane]-2',3-dione Spironolactone Related CoMpound A Pregna-4,6-diene-21-carboxylicacid, 17-hydroxy-3-oxo-, g-lactone, (17a)- Canrenone 17-hydroxy-3-oxo-17a-pregna-4,6-diene-21-carboxylic acid gamma-lactone NSC 261713 7-Carboxy-9(11)&Delta kanlitong Spironolactone Impurity 6(Spironolactone EP Impurity F) Spironolactone EP Impurity F Eplerenone Impurity 28 10,13-Dimethylspiro[2,8,9,11,12,14,15,16-octahydro-1H-cyclopenta[a]phenanthrene-17,5'-oxolane]-2',3-dione Canrenone Solution, 100ppm Eplerenone Canrenone Impurity Canrenone CRS 6,7-Dehydro-7α-desthioacetylspironolactone RP-11614 Spironolactone EP Impurity F-d4 (Canrenone-d4) Pregna-4,6-diene-21-carboxylic acid, 17-hydroxy-3-oxo-, γ-lactone, (17α)- Spironolactone EP Impurity F (Canrenone) 7-Carboxy-9(11)Δ-canrenone Spiranolactone Impurity F Canrenone D7Q: What is Canrenone D7 Q: What is the CAS Number of Canrenone D7 Q: What is the storage condition of Canrenone D7 Q: What are the applications of Canrenone D7 CanrenoneQ: What is Canrenone Q: What is the CAS Number of Canrenone Q: What is the storage condition of Canrenone Q: What are the applications of Canrenone Spironolactone Related Compound A (Canrenone (3-Oxo-17-alpha-pregna-4,6-diene-21, 17-carbolactone)) (1619017) CANRENONE-D4 Candy, ketone 6,7-Dehydro-7α-desthioacetylspironolactone Spironolactone USP Related Compound A