Eplerenone 7-Carboxylic Acid Impurity

Eplerenone 7-Carboxylic Acid Impurity Structure
CAS No.
209253-82-7
Chemical Name:
Eplerenone 7-Carboxylic Acid Impurity
Synonyms
Eplerenone EP Imp D;Eplerenone Impurity D;Eplerenone EP Impurity D;FLTCRAGDAAVKPG-ALROZPJCSA-N;Eplerenone 7-Carboxylic Acid Impurity;Eplerenone Impurity 15(Eplerenone EP Impurity D);7alpha-Carboxy-9,11alpha-epoxy-3-oxo-17alpha-pregn-4-ene-21,17-carbolactone;Pregn-4-ene-7,21-dicarboxylic acid, 9,11-epoxy-17-hydroxy-3-oxo-, γ-lactone, (7α,11α,17α)-;(2′R)-9α,11α-Epoxy-3′,4′-dihydro-3,5′-dioxospiro[androst-4-ene-17,2′-furan]-7α-carboxylic Acid;(2'R,4aS,4bR,5aR,6aS,10R)-4a,6a-dimethyl-2,5'-dioxo-3,4,4a,4',5a,5',6,6a,8,9,9a,9b,10,11-tetradecahydro-2H,3'H-spiro[cyclopenta[1,2]phenanthro[4,4a-b]oxirene-7,2'-furan]-10-carboxylic acid
CBNumber:
CB93366010
Molecular Formula:
C23H28O6
Molecular Weight:
400.47
MOL File:
209253-82-7.mol
MSDS File:
SDS
Modify Date:
2023/5/15 10:43:57

Eplerenone 7-Carboxylic Acid Impurity Properties

Boiling point 653.0±55.0 °C(Predicted)
Density 1.37±0.1 g/cm3(Predicted)
solubility Chloroform (Slightly, Heated, Sonicated), DMSO (Slightly), Ethyl Acetate (Slightly)
pka 4.48±0.60(Predicted)
form Solid
color Off-White to Light Yellow

Eplerenone 7-Carboxylic Acid Impurity Chemical Properties,Uses,Production

Uses

Eplerenone 7-Carboxylic Acid is an impurity of Eplerenone (E588775). Eplerenone is a selective aldosterone receptor antagonist (SARA), structurally similar to Spiranolactone. Eplerenone is used alone or in combination with other medications to treat high blood pressure. Eplerenone is in a class of medications called mineralocorticoid receptor antagonists. It works by blocking the action of aldosterone, a natural substance in the body that raises blood pressure.

Eplerenone 7-Carboxylic Acid Impurity Preparation Products And Raw materials

Raw materials

Preparation Products

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Eplerenone Impurity D FLTCRAGDAAVKPG-ALROZPJCSA-N (2'R,4aS,4bR,5aR,6aS,10R)-4a,6a-dimethyl-2,5'-dioxo-3,4,4a,4',5a,5',6,6a,8,9,9a,9b,10,11-tetradecahydro-2H,3'H-spiro[cyclopenta[1,2]phenanthro[4,4a-b]oxirene-7,2'-furan]-10-carboxylic acid Eplerenone EP Impurity D Eplerenone 7-Carboxylic Acid Impurity Eplerenone Impurity 15(Eplerenone EP Impurity D) Eplerenone EP Imp D Pregn-4-ene-7,21-dicarboxylic acid, 9,11-epoxy-17-hydroxy-3-oxo-, γ-lactone, (7α,11α,17α)- (2′R)-9α,11α-Epoxy-3′,4′-dihydro-3,5′-dioxospiro[androst-4-ene-17,2′-furan]-7α-carboxylic Acid 7alpha-Carboxy-9,11alpha-epoxy-3-oxo-17alpha-pregn-4-ene-21,17-carbolactone 209253-82-7