RS 504393

RS 504393 Structure
CAS No.
300816-15-3
Chemical Name:
RS 504393
Synonyms
RS 504393;RS-504393; RS504393;RS504393 >=98% (HPLC);6-methyl-1'-[2-(5-methyl-2-phenyl-1,3-oxazol-4-yl)ethyl]spir...;CC chemokine receptor,RS504393,Inhibitor,RS 504393,inhibit,CCR,RS-504393;6-Methyl-1'-[2-(5-Methyl-2-phenyl-4-oxazolyl)ethyl]-spiro[4H-3,1-benzoxazine-4,4'-piperidi;6-Methyl-1'-(2-(5-methyl-2-phenyloxazol-4-yl)ethyl)spiro-[benzo[d][1,3]oxazine-4,4'-piperidin];6-Methyl-1'-(2-(5-methyl-2-phenyloxazol-4-yl)ethyl)spiro-[benzo[d][1,3]oxazine-4,4'-piperidin]-2(;6-Methyl-1'-[2-(5-methyl-2-phenyl-4-oxazolyl)ethyl]-spiro[4H-3,1-benzoxazine-4,4'-piperidin]-2(1H)-one;6-Methyl-1'-[2-(5-methyl-2-phenyl-4-oxazolyl)ethyl]-spiro[4H-3,1-benzoxazine-4,4'-piperidin]-2(1H)-one
CBNumber:
CB5837883
Molecular Formula:
C25H27N3O3
Molecular Weight:
417.5
MOL File:
300816-15-3.mol
MSDS File:
SDS
Modify Date:
2023/6/30 15:45:59

RS 504393 Properties

Density 1.28
storage temp. 2-8°C
solubility DMSO: soluble1mg/mL, clear (warmed)
form powder
color white to beige

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P305+P351+P338
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26
WGK Germany  3
NFPA 704
0
2 0

RS 504393 price More Price(2)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) SML0711 RS504393 ≥98% (HPLC) 300816-15-3 5MG ₹14418.9 2022-06-14 Buy
Sigma-Aldrich(India) SML0711 RS504393 ≥98% (HPLC) 300816-15-3 25MG ₹58054.48 2022-06-14 Buy
Product number Packaging Price Buy
SML0711 5MG ₹14418.9 Buy
SML0711 25MG ₹58054.48 Buy

RS 504393 Chemical Properties,Uses,Production

Uses

RS 504393 is a small molecule antagonist at the CC chemokine receptor 2.

Biological Activity

Extremely selective CCR2 chemokine receptor antagonist (IC 50 values are 98 nM and > 100 μ M for inhibition of human recombinant CCR2b and CCR1 receptors respectively). Inhibits MCP-1 chemotaxis (IC 50 = 330 nM) and ischemia-reperfusion injury in kidneys.

Biochem/physiol Actions

RS504393 is a highly selective CCR2 chemokine receptor antagonist. RS504393 inhibits MCP-1 chemotaxis and ischemia-reperfusion injury in kidneys.

RS 504393 Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 88)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
CHEMSWORTH +91-261-2397244 New Delhi, India 6707 30 Inquiry
CONIER CHEM AND PHARMA LIMITED +8618523575427 China 49391 58 Inquiry
career henan chemical co +86-0371-86658258 +8613203830695 China 29826 58 Inquiry
Apeloa Pharmaceutical Co., Ltd. +86-0571-87635730 +8615858229168 China 1478 58 Inquiry
InvivoChem +1-708-310-1919 +1-13798911105 United States 6393 58 Inquiry
Hefei TNJ Chemical Industry Co.,Ltd. 0551-65418684 +8618949823763 China 25363 58 Inquiry
Henan Aochuang Chemical Co.,Ltd. +86-0371-63689365 +8618638391208 China 9425 58 Inquiry
TargetMol Chemicals Inc. +1-781-999-5354 United States 19973 58 Inquiry
Wuhan Topule Biopharmaceutical Co., Ltd +8618327326525 China 8474 58 Inquiry
Aladdin Scientific +1-+1(833)-552-7181 United States 57511 58 Inquiry

RS 504393 Spectrum

Spiro[4H-3,1-benzoxazine-4,4'-piperidin]-2(1H)-one, 6-Methyl-1'-[2-(5-Methyl-2-phenyl-4-oxazolyl)ethyl]- 6-Methyl-1'-[2-(5-Methyl-2-phenyl-4-oxazolyl)ethyl]-spiro[4H-3,1-benzoxazine-4,4'-piperidi 6-Methyl-1'-(2-(5-Methyl-2-phenyloxazol-4-yl)ethyl)spiro[benzo[d][1,3]oxazine-4,4'-piperidin]-2(1H)-one 6-Methyl-1'-(2-(5-methyl-2-phenyloxazol-4-yl)ethyl)spiro-[benzo[d][1,3]oxazine-4,4'-piperidin]-2( 6-Methyl-1'-(2-(5-methyl-2-phenyloxazol-4-yl)ethyl)spiro-[benzo[d][1,3]oxazine-4,4'-piperidin] RS 504393 6-Methyl-1'-[2-(5-methyl-2-phenyl-4-oxazolyl)ethyl]-spiro[4H-3,1-benzoxazine-4,4'-piperidin]-2(1H)-one RS-504393; RS504393 RS504393 >=98% (HPLC) 6-methyl-1'-[2-(5-methyl-2-phenyl-1,3-oxazol-4-yl)ethyl]spir... CC chemokine receptor,RS504393,Inhibitor,RS 504393,inhibit,CCR,RS-504393 6-Methyl-1'-(2-(5-methyl-2-phenyloxazol-4-yl)ethyl)spiro[benzo[d][1,3]oxazine-4,4'-piperidin]-2(1H)-one 6-Methyl-1'-[2-(5-methyl-2-phenyl-4-oxazolyl)ethyl]-spiro[4H-3,1-benzoxazine-4,4'-piperidin]-2(1H)-one 300816-15-3