5-hydroxy-l-tryptophan
![5-hydroxy-l-tryptophan Structure](CAS/GIF/314062-44-7.gif)
- CAS No.
- 314062-44-7
- Chemical Name:
- 5-hydroxy-l-tryptophan
- Synonyms
- 5-HYDROXY-L-TRYPTOPHAN;5-HTP;L-5-HTP;L-HTP-OH;H-TRP(5-OH)-OH;5-HYDROXY-TRP-OH;H-5-HYDROXY-TRP-OH;5-HYDROXY-L-TRP-OH;C5-HYDROXY-L-TRYPTOPHAN;L-5-HYDROXYTRYPTOPHAN HYDRATE
- CBNumber:
- CB6110024
- Molecular Formula:
- C11H12N2O3
- Molecular Weight:
- 220.22
- MOL File:
- 314062-44-7.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/3/28 13:39:29
Melting point | 270 °C (dec.)(lit.) |
---|---|
Density | 0.902 g/mL at 25 °C(lit.) |
refractive index |
n |
Flash point | 175 °F |
storage temp. | Keep in dark place,Inert atmosphere,2-8°C |
solubility | H2O: 10 mg/mL |
form | solid |
color | white |
InChI | InChI=1/C11H12N2O3/c12-9(11(15)16)3-6-5-13-10-2-1-7(14)4-8(6)10/h1-2,4-5,9,13-14H,3,12H2,(H,15,16)/t9-/s3 |
InChIKey | LDCYZAJDBXYCGN-DJEYLCQNNA-N |
SMILES | C12C=C(C=CC=1NC=C2C[C@H](N)C(=O)O)O |&1:10,r| |
CAS DataBase Reference | 314062-44-7(CAS DataBase Reference) |
5-hydroxy-l-tryptophan Chemical Properties,Uses,Production
Description
5-hydroxy-l-tryptophan (5-HTP) is a chemical byproduct of the protein building block L-tryptophan. It is produced commercially from the seeds of an African plant known as Griffonia simplicifolia. In vivo, it is produced from tryptophan by tryptophan hydroxylase (TPH), and its decarboxylation yields serotonin (5-hydroxytryptamine, 5-HT), a monoamine neurotransmitter involved in the modulation of mood, cognition, reward, learning, memory, sleep, and numerous other physiological processes. 5-HTP is both a drug and a natural component of some dietary supplements, and occurrence in both synthetic tryptophan and 5-HTP of toxic impurities has caused eosinophilia myalgia syndrome cases[1].
Uses
5-hydroxy-l-tryptophan is metabolized into serotonin and is thought to alleviate depression by enhancing serotonin neurotransmission. It is also used to treat fibromyalgia, insomnia, binge-eating, attention deficit disorder, and chronic headaches.
References
[1] Maffei, Massimo E. "5-Hydroxytryptophan (5-HTP): Natural Occurrence, Analysis, Biosynthesis, Biotechnology, Physiology and Toxicology." International Journal of Molecular Sciences 22.1(2021):181.
5-hydroxy-l-tryptophan Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | Inquiry |
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Sigma Audley | +86-18336680971 +86-18126314766 | China | 497 | 58 | Inquiry |
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BINBO BIOLOGICAL CO.,LTD | +8618629063126 | China | 346 | 58 | Inquiry |
Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | China | 29798 | 60 | Inquiry |
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | China | 21676 | 55 | Inquiry |
Jinan Jianfeng Chemical Co., Ltd | 0531-88110457; +8615562555968 | China | 225 | 58 | Inquiry |
Xi'an Kono chem co., Ltd., | 029-86107037 13289246953 | China | 2995 | 58 | Inquiry |
CONIER CHEM AND PHARMA LIMITED | +8618523575427 | China | 49391 | 58 | Inquiry |
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