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Irinotecan hydrochloride trihydrate

CAS No.: 136572-09-3

Chemical Name:: Irinotecan hydrochloride trihydrate

Synonyms: Iriontecan HCL;Irinotecan HCL 3H2O;Irinotecan HydrochL;Irinotecan Trihydrate;CPT-11 HCl Trihydrate;Irinotecan Hydrochlorid;IRINOTECON HCL TRIHYDRATE;IRINOTECAN HCL TRIHYDRATE;Irinotecan HCI Trihydrate;trihydrate,(s)-hydrochlorid

CBNumber:: CB6122430

Molecular Formula:: C33H45ClN4O9

Molecular Weight:: 677.18

MOL File:: 136572-09-3.mol

Modify Date:: 2023/9/11 17:45:53

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Irinotecan hydrochloride trihydrate Properties

Melting point	250-256°C (dec.)
Boiling point	257°C(lit.)
storage temp.	2-8°C
solubility	Soluble in DMSO (up to 50 mg/ml), in Water (up to 4 mg/ml) or in Ethanol (up to 4 mg/ml).
form	White solid.
color	Yellow
Water Solubility	Soluble in DMSO at 100mg/ml. Soluble in water at 25mg/ml with warming
Merck	14,5091
Stability	Stable for 1 year from date of purchase as supplied. Solutions in DMSO, ethanol or distilled water may be stored at -20° for up to 3 months.
CAS DataBase Reference	136572-09-3(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07,GHS08

Signal word

Danger

Hazard statements

H302-H372

Precautionary statements

P260-P264b-P270-P301+P312-P314-P330-P403-P501c

Risk Statements

Safety Statements

20/21-22

RTECS

DW1060750

HS Code

29349990

Toxicity

dog,LD50,intravenous,40mg/kg (40mg/kg),Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 26, Pg. 953, 1995.

NFPA 704

	0
1		0

Irinotecan hydrochloride trihydrate price More Price(2)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
TCI Chemicals (India)	I0714	Irinotecan Hydrochloride Trihydrate	136572-09-3	100MG	₹11800	2022-05-26	Buy
ottokemi	I 0692	Irinotecan hydrochloride	136572-09-3	100mg	₹136089	2022-05-26	Buy

Product number	Packaging	Price	Buy
I0714	100MG	₹11800	Buy
I 0692	100mg	₹136089	Buy

Irinotecan hydrochloride trihydrate Chemical Properties,Uses,Production

Chemical Properties

White powder

Uses

Irinotecan Hydrochloride Trihydrate is a DNA topoisomerase inhibitor.

Definition

ChEBI: A hydrate that is the trihydrate form of irinotecan hydrochloride. Onivyde is used in combination with fluorouracil and leucovorin, for the treatment of patients with metastatic adenocarcinoma of the pancreas after disease progression following gemcitabine based therapy. It is converted via hydrolysis of the carbamate linkage to its active metabolite, SN-38, which is ~1000 times more active.

Hazard

Moderately toxic by ingestion.

Irinotecan hydrochloride trihydrate Preparation Products And Raw materials

Raw materials

Irinotecan hydrochloride

Preparation Products

Irinotecan hydrochloride trihydrate Suppliers

Global( 478)Suppliers

Supplier	Tel	Country	ProdList	Advantage	Inquiry
Cipla Ltd	+912224826000	Maharashtra, India	133	58	Inquiry
Beta Drugs	+91-9316590666 +91-7015991921	Haryana, India	34	58	Inquiry
Shilpa Medicare Limited (SML)	+91-8532238704 +91-9320649838	Karnataka, India	61	58	Inquiry
Basil Drugs AND Pharmaceuticals Pvt Ltd	+91-2249700250 +91-9619320820	Mumbai, India	108	58	Inquiry
Sun Pharmaceutical Industries Ltd.	91-22-43244324	Maharashtra, India	99	58	Inquiry
Manus Aktteva	+91 (79) 6512-3395	New Delhi, India	581	34	Inquiry
FRESENIUS KABI ONCOLOGY LTD	+86-571-28971376	New Delhi, India	21	58	Inquiry
MAC CHEM PRODUCTS INDIA PVT LTD	+91 22 4093 9000 / 01	New Delhi, India	13	58	Inquiry
LAURUS LABS LTD	+91 891 306 1222	New Delhi, India	43	58	Inquiry
ARCH PHARMALABS LTD	+91-22-4287-1210	New Delhi, India	15	58	Inquiry

Supplier	Advantage
Cipla Ltd	58
Beta Drugs	58
Shilpa Medicare Limited (SML)	58
Basil Drugs AND Pharmaceuticals Pvt Ltd	58
Sun Pharmaceutical Industries Ltd.	58
Manus Aktteva	34
FRESENIUS KABI ONCOLOGY LTD	58
MAC CHEM PRODUCTS INDIA PVT LTD	58
LAURUS LABS LTD	58
ARCH PHARMALABS LTD	58

Irinotecan hydrochloride trihydrate Spectrum

Irinotecan hydrochloride trihydrate(136572-09-3)¹HNMR

136572-09-3(Irinotecan hydrochloride trihydrate)Related Search:

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Irinotecan-d10 hydrochloride trihydrate CPT-11 HCl Trihydrate irinotecan hydrochloride hydrate Irinotecanhydrochloridetrihydrate(CPT-11) IRINOTECON HCL TRIHYDRATE [1,4'-BIPIPERIDINE]-1'-CARBOXYLIC ACID (S)-4,11-DIETHYL-3,4,12,14-TETRAHYDRO-4-HYDROXY-3,14-DIOXO-1H-PYRANO[3',4',6,7]INDOLIZINO[1,2-B]QUINOLIN-9-YL ESTER, HCL TRIHYDRATE (S)-[1,4'-Bipiperidine]-1'-carboxylic acid 4,11-diethyl-3,4,12,14-tetrahydro-4-hydroxy-3,14-dioxo-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinolin-9-yl ester hydrochloride trihydrate ,99% Irinotecan Hydrochloride (100 mg) Irinotecan Hydrochloride Irinotecan Trihydrate [1,4'-Bipiperidine]-1'-carboxylicacid,(4S)-4,11-diethyl-3,4,12,14-tetrahydro-4-hydroxy-3,14-dioxo-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinolin-9-ylester,hydrochloride,hydrate(1:1:3) Irinotecan HCl Trihydrate (CaMpto) Irinotecan, Hydrochloride Salt, Trihydrate Irinotecan hydrochloride trihydrate, >=99% (1,4’-bipiperidine)-1’-carboxylicacid,4,11-diethyl-3,4,12,14-tetrahydro-4-hyd roxy-3,14-dioxo-1h-pyrano(3’,4’:6,7)indolizino(1,2-b)quinolin-9-ylester,mono trihydrate,(s)-hydrochlorid IRINOTECAN HYDROCHLORIDE TRIHYDRATE IRINOTECAN MONOHYDROCHLORIDE TRIHYDRATE IRINOTECAN HCL TRIHYDRATE Irinotecan HCL 3H2O rinotecan hydrochloride trihydrate (s)-[1,4'-bipiperidine]-1'-carboxylic acid 4,11-diethyl-3,4,12,14-tetrahydro-4-hydroxy-3,14-dioxo-1h-pyrano[3',4':6,7]indolizino[1,2-b]quinolin-9-yl ester hydrochloride trihydrate Irinotecan Hydrochlorid 7-Ethyl-10-[4-(1-piperidino)-1-piperidino]carbonyloxycamptothecin Hydrochloride Trihydrate Irinotecan hydrochloride trihydrate CRS Irinotecan for peak identification Irinotican Hydrochloride Trihydrate IrinotecanHydrochlorideTrihydrate> Irinotecan HydrochL Irincan hydrochloride trihydrate Irinotecan hydrochloride trihydrate USP/EP/BP Irinotican Hydrochloride TrihydrateQ: What is Irinotican Hydrochloride Trihydrate Q: What is the CAS Number of Irinotican Hydrochloride Trihydrate Q: What is the storage condition of Irinotican Hydrochloride Trihydrate Q: What are the applications of Irinotican Hydrochloride Trihydrate Irinotecan for peak identification (Y0001831) Irinotecan for system suitability 1 (Y0001830) Irinotecan for system suitability 2 (Y0001833) Irinotecan Hydrochloride (1347609) Irinotecan hydrochloride trihydrate (Y0001832) Iriontecan HCL CPT 11; CAMPTOSAR; CAMPTO; IRINOTECAN Irinotecan HCI Trihydrate (S)-4,11-diethyl-4-hydroxy-3,14-dioxo-3,4,12,14-tetrahydro-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinolin-9-yl [1,4'-bipiperidine]-1'-carboxylate hydrochloride trihydrate Irinotecan hydrochloride trihydrate 98% (S)-4,11-Diethyl-3,4,12,14-tetrahydro-4-hydroxy-3,14-dioxo-1H-pyrano[3’,4’:6,7]indolizino[1,2-b]quinolin-9-yl [1,4’-Bipiperidine]-1’-carboxylate Hydrochloride Trihydrate Irinotecan (CPT-11) HCl Trihydrate (S)-4,11-Diethyl-4-hydroxy-3,14-dioxo-3,4,12,14-tetrahydro-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinolin-9-yl [1,4'-bipiperidine]-1'-carboxylate hydrochloride trihydrate (S)-4,11-Diethyl-3,4,12,14-tetrahydro-4-hydroxy-3,14-dioxo-1H-pyrano[3’,4’:6,7]indolizino[1,2-b]quinolin-9-yl [1,4’-Bipiperidine]-1’-carboxylate Hydrochloride Trihydrate 136572-09-3 6572-09-3 36572-09-3 C33H38N4O6HCl3H2O C33H38N4O6ClH3H2O C33H45ClN4O9 Inhibitors Anticancer Anti-cancer&immunity API