Marbofloxacin
- CAS No.
- 115550-35-1
- Chemical Name:
- Marbofloxacin
- Synonyms
- Marbofloxacine;9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-3,7-dihydro-2H-[1,3,4]oxadiazino[6,5,4-ij]quinoline-6-carboxylic acid;CS-939;Marbocyl;zeniquin;ZENIQUIN(R);Ma Bo effect;MARBOFLOXACIN;Marbifloxacin;Marboflaxacine
- CBNumber:
- CB6125860
- Molecular Formula:
- C17H19FN4O4
- Molecular Weight:
- 362.36
- MOL File:
- 115550-35-1.mol
- Modify Date:
- 2024/8/21 22:41:43
| Melting point | 268-269°C (dec.) |
|---|---|
| Boiling point | 571℃ |
| Density | 1.55±0.1 g/cm3(Predicted) |
| Flash point | >110°(230°F) |
| storage temp. | Inert atmosphere,2-8°C |
| solubility | Chloroform (Slightly, Heated) |
| pka | 6.02±0.20(Predicted) |
| form | Solid |
| color | Light Yellow |
| Water Solubility | Soluble in DMSO at 2mg/ml. Soluble in water or ethanol at <1mg/ml |
| Merck | 14,5750 |
| InChI | InChI=1S/C17H19FN4O4/c1-19-3-5-21(6-4-19)14-12(18)7-10-13-16(14)26-9-20(2)22(13)8-11(15(10)23)17(24)25/h7-8H,3-6,9H2,1-2H3,(H,24,25) |
| InChIKey | BPFYOAJNDMUVBL-UHFFFAOYSA-N |
| SMILES | N12C=C(C(O)=O)C(=O)C3=C1C(=C(N1CCN(C)CC1)C(F)=C3)OCN2C |
| CAS DataBase Reference | 115550-35-1(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H412 | |||||||||
| Precautionary statements | P273-P501 | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 52/53-36/37/38 | |||||||||
| Safety Statements | 61-36-26-60 | |||||||||
| WGK Germany | 2 | |||||||||
| RTECS | UU8815140 | |||||||||
| HS Code | 29349990 | |||||||||
| NFPA 704 |
|
Marbofloxacin price More Price(3)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | 34039 | Marbofloxacin VETRANAL?, analytical standard | 115550-35-1 | 100MG | ₹13931.78 | 2022-06-14 | Buy |
| TCI Chemicals (India) | M2240 | Marbofloxacin | 115550-35-1 | 1G | ₹7000 | 2022-05-26 | Buy |
| TCI Chemicals (India) | M2240 | Marbofloxacin | 115550-35-1 | 5G | ₹14500 | 2022-05-26 | Buy |
Marbofloxacin Chemical Properties,Uses,Production
Description
Marbofloxacin is a fluoroquinolone antibiotic that is active against P. multocida in vitro (MIC = 0.016 μg/ml). It exhibits broad-spectrum antibacterial activity mediated by the inhibition of DNA gyrase, with MIC values ranging from 0.016 to 0.4 and 0.19 to 1.7 μg/ml against various Gram-negative and Gram-positive bacterial isolates, respectively. In vivo, the administration of marbofloxacin (2 mg/kg, i.m.) after infection prevents the formation of pulmonary lesions in a bovine calf model of M. haemolytica A1 pneumonia. Oral marbofloxacin (2 mg/kg per day) also exhibits antileishmanial activity in a canine model of leishmaniasis, decreasing parasitic load by 72%. Formulations containing marbofloxacin have been used in the veterinary treatment of bacterial infections.
Chemical Properties
Crystalline Solid
Uses
Fluorinated quinolone antibacterial
Definition
ChEBI: A fluoroquinolone antibiotic that is 7-oxo-2,3-dihydro-7H-[1,3,4]oxadiazino[6,5,4-ij]quinoline substituted at positions 6, 9 and 10 by carboxy, fluoro and 4-methylpiperazin-1-yl groups, respectively. A synthetic, broad spect um bactericidal agent, it is used in veterinary medicine, although its mechanism of action is not thoroughly understood.
Application
Marbofloxacin is an FDA-approved broad-spectrum bactericidal fluoroquinolone available in oral tablet and injectable forms. It has been shown to have varying therapeutic effects in a wide range of animal diseases in dogs, cats, horses, cattle and pigs. It can be used to treat skin and soft tissue infections in dogs and cats, urinary tract infections in dogs, some blood borne pathogens (e.g. Mycoplasma haematobium) in cats, equine infections caused by susceptible bacteria, bovine respiratory disease, and porcine respiratory disease pathogens.
Side effects
The most common side effects of Marbofloxacin are vomiting, diarrhoea and loss of appetite. More serious side effects include cartilage abnormalities (which may cause difficulty walking), prolonged loss of appetite, incoordination, convulsions, depression, fever, rash, or difficulty breathing. Blindness and eye damage in cats has been a concern at high doses.
Marbofloxacin Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| NGL Fine Chem limited | +91-8866366396 +91-8866366396 | Mumbai, India | 26 | 58 | Inquiry |
| Diligent Life Care | +91-2262515000 +91-9898023247 | Gujarat, India | 12 | 58 | Inquiry |
| Turtle Pharma Private Limited | +91-9850998504 +91-9850998504 | Maharashtra, India | 27 | 58 | Inquiry |
| Heer Pharma Pvt Ltd | +91-9820051881 +91-9820051881 | Maharashtra, India | 102 | 58 | Inquiry |
| NGL Fine-chem Ltd | 91-22-26636450 | Maharashtra, India | 7 | 58 | Inquiry |
| A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
| Gliesse Pharmaceuticals Pvt., Ltd. | 91-79-40052081 | Gujarat, India | 165 | 58 | Inquiry |
| AURORE LIFE SCIENCES PRIVATE LIMITED | +91-40-2311 3211 | New Delhi, India | 42 | 58 | Inquiry |
| Alivira Animal Health | 91-22-41114777 | Mumbai, India | 9 | 58 | Inquiry |
| Supplier | Advantage |
|---|---|
| NGL Fine Chem limited | 58 |
| Diligent Life Care | 58 |
| Turtle Pharma Private Limited | 58 |
| Heer Pharma Pvt Ltd | 58 |
| NGL Fine-chem Ltd | 58 |
| A.J Chemicals | 58 |
| CLEARSYNTH LABS LTD. | 58 |
| Gliesse Pharmaceuticals Pvt., Ltd. | 58 |
| AURORE LIFE SCIENCES PRIVATE LIMITED | 58 |
| Alivira Animal Health | 58 |
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- Mar 6，2024
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