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Trepibutone

Trepibutone Structure
CAS No.
41826-92-0
Chemical Name:
Trepibutone
Synonyms
aa149;supacal;colibil;TREPIBUTONE;Colibil, Supacal;Trepibutone USP/EP/BP;Trepibutone, 10 mM in DMSO;3-(2,4,5-triethoxybenzoyl)propionicacid;3-(2,4,5-triethoxybenzoyl)-propionicaci;2,4,5-Triethoxy-γ-oxobenzenebutanoic acid
CBNumber:
CB6126519
Molecular Formula:
C16H22O6
Molecular Weight:
310.34
MOL File:
41826-92-0.mol
MSDS File:
SDS
Modify Date:
2024/11/19 23:02:33

Trepibutone Properties

Melting point 150-151°
Boiling point 370.51°C (rough estimate)
Density 1.1625 (rough estimate)
refractive index 1.4600 (estimate)
pka 4.40±0.17(Predicted)
form Solid
color White to off-white
CAS DataBase Reference 41826-92-0(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Trepibutone Chemical Properties,Uses,Production

Originator

Supacal,Takeda,Japan,1981

Manufacturing Process

To a mixture of 7.5 parts by weight of 1,2,4-triethoxybenzene, 40 parts by volume of tetrachloroethane and 7.5 parts by weight of succinic anhydride are added 23 parts by weight of anhydrous aluminum chloride. The mixture is stirred for 1 hour at 25°C and for another 2 hours at 60°C. After addition of 50 parts by weight of ice and 50 parts by volume of concentrated hydrochloric acid, the reaction mixture is subjected to steam distillation.
After cooling crystals separated from the remaining liquid are collected by filtration and recrystallized from aqueous ethanol, whereby 2.5 parts by weight of 3-(2',4',5'-triethoxybenzoyl)-propionic acid are obtained as colorless needles, melting point 150°C to 151°C.

Therapeutic Function

Choleretic

Trepibutone Preparation Products And Raw materials

Global( 106)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
Pharmaffiliates Analytics and Synthetics P. Ltd +91-172-5066494 Haryana, India 6739 58 Inquiry
Pharma Affiliates 172-5066494 Haryana, India 6754 58 Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6257 58 Inquiry
Hebei Mujin Biotechnology Co.,Ltd +86 13288715578 +8613288715578 China 12809 58 Inquiry
career henan chemical co +86-0371-86658258 +8613203830695 China 29858 58 Inquiry
TargetMol Chemicals Inc. +1-781-999-5354 +1-00000000000 United States 32159 58 Inquiry
Hefei TNJ Chemical Industry Co.,Ltd. +86-0551-65418671 +8618949823763 China 34563 58 Inquiry
Win-Win chemical CO., Limited +86-0086-577-64498589 +86-15355981851 China 14442 58 Inquiry
Shaanxi Dideu Medichem Co. Ltd +86-029-89586680 +86-18192503167 China 7859 58 Inquiry
AFINE CHEMICALS LIMITED +86-0571-85134551 China 15395 58 Inquiry

Trepibutone Spectrum

2,4,5-triethoxy-gamma-oxobenzenebutanoicacid 3-(2,4,5-triethoxybenzoyl)-propionicaci 3-(2,4,5-triethoxybenzoyl)propionicacid aa149 colibil supacal TREPIBUTONE 4-Oxo-4-(2,4,5-triethoxyphenyl)butanoic acid 2,4,5-Triethoxy-γ-oxobenzenebutanoic acid 4-(2,4,5-Triethoxyphenyl)-4-oxobutanoic acid Benzenebutanoic acid, 2,4,5-triethoxy-γ-oxo- Trepibutone USP/EP/BP Colibil, Supacal 4-oxo-4-(2,4,5-triethoxyphenyl)butanoicaci Trepibutone, 10 mM in DMSO 41826-92-0