Succinic anhydride
![Succinic anhydride Structure](CAS/GIF/108-30-5.gif)
- CAS No.
- 108-30-5
- Chemical Name:
- Succinic anhydride
- Synonyms
- SAN;succinic;SAA;DIHYDRO-2,5-FURANDIONE;SUCCINIC ACID ANHYDRIDE;SAA1;Dihydro-furan-2,5-dione;BUTANEDIOIC ANHYDRIDE;Bernsteinsaure-anhydrid;Serum amyloid A protein
- CBNumber:
- CB5166246
- Molecular Formula:
- C4H4O3
- Molecular Weight:
- 100.07
- MOL File:
- 108-30-5.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/6/17 17:42:23
Melting point | 118-120 °C (lit.) |
---|---|
Boiling point | 261 °C (lit.) |
Density | 1,572 g/cm3 |
vapor density | 3.5 (vs air) |
vapor pressure | 1 mm Hg ( 92 °C) |
refractive index | 1.4688 (estimate) |
Flash point | 157°C |
storage temp. | Store below +30°C. |
solubility | 62.9g/l Hydrolysis |
form | Solid |
pka | 4.67[at 20 ℃] |
color | White to Off-White |
Specific Gravity | 1.2340 (20℃) |
PH | 2.7 (10g/l, H2O) |
Water Solubility | <0.1 g/100 mL at 21 ºC (decomposes) |
Sensitive | Moisture Sensitive |
Merck | 14,8870 |
BRN | 108441 |
Stability | Stable. Incompatible with oxidising agents, strong acids, strong bases, alcohols, amines. Avoid exposure to water or moisture. |
InChIKey | RINCXYDBBGOEEQ-UHFFFAOYSA-N |
LogP | 2.44 at 40℃ |
CAS DataBase Reference | 108-30-5(CAS DataBase Reference) |
IARC | 3 (Vol. 15, Sup 7) 1987 |
NIST Chemistry Reference | 2,5-Furandione, dihydro-(108-30-5) |
EPA Substance Registry System | Succinic anhydride (108-30-5) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | ![]() GHS05 |
|||||||||
---|---|---|---|---|---|---|---|---|---|---|
Signal word | Warning | |||||||||
Hazard statements | H290 | |||||||||
Precautionary statements | P234-P390 | |||||||||
Hazard Codes | Xi,Xn | |||||||||
Risk Statements | 36/37-22 | |||||||||
Safety Statements | 25-46 | |||||||||
RIDADR | UN 3261 8 / PGII | |||||||||
WGK Germany | 1 | |||||||||
RTECS | WN0875000 | |||||||||
F | 21 | |||||||||
Autoignition Temperature | 480 °C | |||||||||
TSCA | Yes | |||||||||
HS Code | 29171990 | |||||||||
Toxicity | LD50 orally in Rabbit: 1510 mg/kg | |||||||||
NFPA 704 |
|
Succinic anhydride price More Price(17)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich(India) | 8.00683 | Succinic anhydride for synthesis | 108-30-5 | 500G | ₹4750 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | 8.00683 | Succinic anhydride for synthesis | 108-30-5 | 100G | ₹5340.01 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | 8.00683 | Succinic anhydride for synthesis | 108-30-5 | 1KG | ₹6519.99 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | 8.00683 | Succinic anhydride for synthesis | 108-30-5 | 50KG | ₹108180 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | 239690 | Succinic anhydride ≥99% (GC) | 108-30-5 | 50G | ₹6224.38 | 2022-06-14 | Buy |
Succinic anhydride Chemical Properties,Uses,Production
Description
Succinic anhydride, also called di hydro - 2,5- furandione , is an organic compound with the molecular formula C4H4O3.This colorless solid is the acid anhydride of succinic acid.
Chemical Properties
fine white crystalline solid
Chemical Properties
Succinic anhydride is an odourless, colourless needle-like or white crystalline solid natural product. Molecular formula C4H4O3, molecular weight 100.07 g/mol, relative density 1.503, melting point 237 °F. 239 °F at 5 mmHg, 239 °F at 198 °F and 1 mmHg. Soluble in chloroform, carbon tetrachloride, and ethanol; very slightly soluble in ether and water (insoluble in water). Moderately toxic and irritating, emits pungent and irritating fumes when heated to decomposition.
Uses
Succinic Anhydride is an acidulant that hydrolyzes very slowly to succinic acid in water. it has thermal stability and a low melting point of 118°c which permits it to be used in products at compara- tively low temperatures. it is used as a leavening acidulant for bak- ing powder.
Preparation
A solution of succinic acid (500 mg, 42 mmol) and triethylamine (1.23 mL, 42 mmol) in anhydrous THF (120 mL) was allowed to react with triphosgene (42 mg, 7.0 mmol) at ice-water temperature for 10 min. The reaction mixture was subsequently stirred for a further 15 min at room temperature. The solution was then filtered, and the filtrate was concentrated to dryness. The residue was crystallized from ethyl acetate to afford the desired product as white crystals (370 mg, 85%).
Production Methods
The compound is produced from succinic anhydride and hydrogen peroxide . This material must be stabilized by using a dehydrating agent such as disodium sulfate or magnesium sulfate.
Application
Alkyl succinic anhydride (ASA) is used as a sizing agent or wet strength additive in paper production.
General Description
Colorless needles or white crystalline solid. Melting point 237°F. Sublimes at 239°F at 5 mm Hg pressure; and at 198°F and 1 mm Hg pressure. Moderately toxic and an irritant.
General Description
Succinic anhydride is a cyclic anhydride of succinic acid with a five-membered ring. It is widely used in the manufacture of polymeric materials, pharmaceuticals, agrochemicals, dyes, surface-active agents, and organic flame-retardant materials. It also finds application as a cross-linking agent in ion-exchange membranes and a curing agent for epoxy resins.
Air & Water Reactions
Reacts slowly with water. Insoluble in water.
Reactivity Profile
Succinic anhydride reacts exothermically with water. Reactions are usually slow, but might become violent if local heating accelerates their rate. Acids accelerate the reaction with water. Incompatible with acids, strong oxidizing agents, alcohols, amines, and bases.
Fire Hazard
Flash point data for Succinic anhydride are not available, however, Succinic anhydride is probably combustible.
Materials Uses
Succinic anhydride can be used:
(1) In the preparation of covalently cross-linked oxidized-alginate/N-succinyl-chitosan hydrogels, as injectable systems towards tissue engineering.
(2) In preparing functionalized oxide surfaces on a chip.
(3) As a starting material to synthesize polyesters in presence of a metal triflate as a catalyst.
(4) As a cross-linking agent to enhance the mechanicalproperties and antimicrobial activities of zein films.
Safety Profile
Experimental teratogenic effects. Moderately toxic by ingestion. A severe eye irritant. Mutation data reported. Questionable carcinogen with experimental neoplastigenic data. When heated to decomposition it emits acrid smoke and irritating fumes. See also ANHYDRIDES.
Purification Methods
Crystallise the anhydride from redistilled acetic anhydride or CHCl3, then filter, wash with diethyl ether and dry it in a vacuum. [Beilstein 17 H 606, 17 V 6.]
Succinic anhydride Preparation Products And Raw materials
Raw materials
1of2
chevron_rightPreparation Products
1of6
chevron_rightSupplier | Tel | Country | ProdList | Advantage | Inquiry |
---|---|---|---|---|---|
BTC pharm India | +918790379245 | AndhraPradesh, India | 1269 | 58 | Inquiry |
ANJI BIOSCIENCES | +91-9000100077 +91-9000100077 | Hyderabad, India | 430 | 58 | Inquiry |
Shiv Enterprise | +91-9822612471 +91-9822612471 | Maharashtra, India | 10 | 58 | Inquiry |
JSK Chemicals | +919879767970 | Gujarat, India | 3756 | 58 | Inquiry |
Otto Chemie Pvt Ltd | +91-2222070099 +91-2266382599 | Maharashtra, India | 429 | 58 | Inquiry |
TCI Chemicals (India) Pvt. Ltd. | 1800 425 7889 | New Delhi, India | 6778 | 58 | Inquiry |
A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
Maas Pharma Chemicals | +91-9958666224 | Delhi, India | 1607 | 58 | Inquiry |
CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
Alfa Aesar | 1 800 209 7001 | Maharashtra, India | 6913 | 58 | Inquiry |
Supplier | Advantage |
---|---|
BTC pharm India | 58 |
ANJI BIOSCIENCES | 58 |
Shiv Enterprise | 58 |
JSK Chemicals | 58 |
Otto Chemie Pvt Ltd | 58 |
TCI Chemicals (India) Pvt. Ltd. | 58 |
A.J Chemicals | 58 |
Maas Pharma Chemicals | 58 |
CLEARSYNTH LABS LTD. | 58 |
Alfa Aesar | 58 |
Related articles
- Succinic Anhydride: Applications in Surface Modification and Sustainable Production
- Sustainable production of succinic anhydride from biomass using visible light-induced oxygenation with H2TPP enhances CNC prop....
- May 31,2024
- The solubility of Succinic anhydride
- Succinic anhydride is a white crystal with wide use and optimum application prospects.
- May 11,2024
- Succinic anhydride: applications in diverse industries
- Succinic anhydride is a compound that is commonly used in various applications.
- Jul 3,2023