Amprolium
- CAS No.
- 121-25-5
- Chemical Name:
- Amprolium
- Synonyms
- AMPROLIUM;Amprolium HCI;AMproliuM, USP;Amprolium [INN:BAN];Amprolium USP/EP/BP;AMPROLIUM USP 26, BPV 98;Venlafaxine Impurity 1-d6;amprolium/amprolium hydrochloride;(1-(4-AMINO-2-PROPYL-5-PYRIMIDINYL)-METHYL)-2-METHYLPYRID.;1-((4-Amino-2-propyl-5-pyrimidinyl)methyl)-2-picolinium chloride
- CBNumber:
- CB6127743
- Molecular Formula:
- C14H19N4.Cl
- Molecular Weight:
- 278.79
- MOL File:
- 121-25-5.mol
- Modify Date:
- 2023/12/13 14:53:42
| Melting point | 246-248 °C (decomp) |
|---|---|
| storage temp. | 0-6°C |
| solubility | Soluble in DMSO |
| color | Crystals from methanol + ethanol |
| Stability | Stable. Incompatible with strong acids, strong bases, strong oxidizing agents. |
| InChI | InChI=1S/C14H19N4.ClH/c1-3-6-13-16-9-12(14(15)17-13)10-18-8-5-4-7-11(18)2;/h4-5,7-9H,3,6,10H2,1-2H3,(H2,15,16,17);1H/q+1;/p-1 |
| InChIKey | LCTXBFGHZLGBNU-UHFFFAOYSA-M |
| SMILES | C1(C=NC(CCC)=NC=1N)C[N+]1C=CC=CC=1C.[Cl-] |
| CAS DataBase Reference | 121-25-5(CAS DataBase Reference) |
| EPA Substance Registry System | Amprolium (121-25-5) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P280-P301+P312-P302+P352-P305+P351+P338 |
Amprolium Chemical Properties,Uses,Production
Description
Amprolium is an antiprotozoal agent used for the prevention of coccidiosis in poultry.
Chemical Properties
solid
Uses
Coccidiostat (for poultry).
Uses
Amprolium is an oral coccidiostat, a thiamine analogue, which is used for the prevention and treatment of intestinal coccidiosis . It is used as a feed additive for livestock, sometimes administered in the food or drinking water of puppies and kittens, and in chickens and calves.
Definition
ChEBI: An organic chloride salt having 1-[(4-amino-2-propylpyrimidin-5-yl)methyl]-2-methylpyridin-1-ium as the counterion. Used for prevention of coccidiosis in poultry and cattle.
Contact allergens
Amprolium is an antiprotozoal agent used for the prevention of coccidiosis in poultry.
Side effects
Amprolium is considered one of the safest anticoccidial medications, and adverse reactions such as anorexia or diarrhoea may occur with high doses and prolonged use. Thiamine deficiency can cause central nervous system (CNS) symptoms, but can be reversed with the addition of thiamine to the diet. However, thiamine supplementation may affect the efficacy of the drug.
Safety Profile
When heated to decomposition emits toxic fumes of Cl-.
Amprolium Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
| Pharmaffiliates Analytics and Synthetics P. Ltd | +91-172-5066494 | Haryana, India | 6773 | 58 | Inquiry |
| Solvay Group | 08048372813Ext 823 | Mumbai, India | 10 | 58 | Inquiry |
| Pharma Affiliates | 172-5066494 | Haryana, India | 6761 | 58 | Inquiry |
| shandong perfect biotechnology co.ltd | +86-53169958659; +8618596095638 | China | 294 | 58 | Inquiry |
| Hebei Mojin Biotechnology Co., Ltd | +8613288715578 | China | 12455 | 58 | Inquiry |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | China | 21669 | 55 | Inquiry |
| Hebei Guanlang Biotechnology Co., Ltd. | +86-19930503282 | China | 8822 | 58 | Inquiry |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | China | 49391 | 58 | Inquiry |
| career henan chemical co | +86-0371-86658258 +8613203830695 | China | 29826 | 58 | Inquiry |
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