Amprolium Hydrochloride

- CAS No.
- 137-88-2
- Chemical Name:
- Amprolium Hydrochloride
- Synonyms
- AMPROLIUM HCL;Amprolio;2-picolinium,1-((4-amino-2-propyl-5-pyrimidinyl)methyl)-,chloride,monohydroc;amprol;amprol25;mepyrium;Amprovine;Ampomycin;CB2101848;thiacoccid
- CBNumber:
- CB2101848
- Molecular Formula:
- C14H20Cl2N4
- Molecular Weight:
- 315.24
- MOL File:
- 137-88-2.mol
- MSDS File:
- SDS
- Modify Date:
- 2025/4/3 17:28:56
Melting point | 239.0 to 243.0 °C |
---|---|
storage temp. | Inert atmosphere,Room Temperature |
solubility | Methanol (Slightly), Water (Slightly) |
form | Powder |
color | White to Off-white |
BRN | 4118699 |
InChI | InChI=1S/C14H19N4.2ClH/c1-3-6-13-16-9-12(14(15)17-13)10-18-8-5-4-7-11(18)2;;/h4-5,7-9H,3,6,10H2,1-2H3,(H2,15,16,17);2*1H/q+1;;/p-1 |
InChIKey | PJBQYZZKGNOKNJ-UHFFFAOYSA-M |
SMILES | C1(C=NC(CCC)=NC=1N)C[N+]1C=CC=CC=1C.Cl.[Cl-] |
CAS DataBase Reference | 137-88-2(CAS DataBase Reference) |
EPA Substance Registry System | Amprolium hydrochloride (137-88-2) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | ![]() GHS08 |
---|---|
Signal word | Danger |
Hazard statements | H317-H334 |
Precautionary statements | P261-P272-P280-P284-P302+P352-P333+P313 |
Hazard Codes | Xn |
Risk Statements | 20/21/22-36/37/38 |
Safety Statements | 22-24/25-36-26 |
WGK Germany | 3 |
RTECS | TJ7565000 |
HS Code | 29335995 |
Amprolium Hydrochloride price More Price(4)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich(India) | A0542 | Amprolium hydrochloride | 137-88-2 | 25G | ₹4611.45 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | 31592 | Amprolium hydrochloride VETRANAL?, analytical standard | 137-88-2 | 250MG | ₹4914.55 | 2022-06-14 | Buy |
TCI Chemicals (India) | A2572 | Amprolium Hydrochloride [for Biochemical Research] | 137-88-2 | 5G | ₹1800 | 2022-05-26 | Buy |
TCI Chemicals (India) | A2572 | Amprolium Hydrochloride [for Biochemical Research] | 137-88-2 | 25G | ₹4600 | 2022-05-26 | Buy |
Amprolium Hydrochloride Chemical Properties,Uses,Production
Description
Amprolium is a thiamine analog and antiprotozoal agent that interferes with thiamine metabolism and inhibits carbohydrate synthesis. It competitively inhibits thiamine uptake by E. tenella schizonts and by chick host intestinal cells (Kis = 7.6 and 326 μM, respectively). It also inhibits hexose formation and pentose utilization ex vivo in isolated lysed rat erythrocytes and in liver, kidney, heart, and intestinal tissue homogenates following dietary administration. Amprolium (1,000 ppm in feed) inhibits oocyst output and sporulation of Eimeria maxima, E. brunetti, and E. acervulina in infected chicks. It also decreases lesion and oocyst scores and mortality of E. tenella-infected chicks following dietary administration of a 125 ppm dose. Amprolium (100 μM) induces apoptosis in PC12 rat adrenal cells and increases the level of cleaved caspase-3. Formulations containing amprolium have been used as coccidiostats in poultry processing.
Chemical Properties
Crystalline powder
Uses
Coccidiostatic;Thiamine transport inhibitor
Definition
MeSH: Amprolium Hydrochloride is a veterinary coccidiostat that interferes with thiamine metabolism.
Contact allergens
Amprolium is an antiprotozoal agent used for the prevention of coccidiosis in poultry.
Amprolium Hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | Inquiry |
---|---|---|---|---|---|
Medi Pharma Drug House | +919930911911 | Mumbai, India | 143 | 58 | Inquiry |
A.J Chemicals | 91-9810153283 | New Delhi, India | 6100 | 58 | Inquiry |
CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6257 | 58 | Inquiry |
Vitus Global Inc | 91-11-40516279 | Delhi, India | 91 | 58 | Inquiry |
TCI Chemicals (India) Pvt. Ltd. | 1800 425 7889 | New Delhi, India | 6768 | 58 | Inquiry |
Biopharmacule Speciality Chemicals P Ltd (India) | +91 40 6462 1866 | Hyderabad, India | 526 | 58 | Inquiry |
Gansai International | 91-40-27425615 | Andhra Pradesh, India | 159 | 58 | Inquiry |
Dilipkumar & Co | 91-22-23540021 | Maharashtra, India | 49 | 58 | Inquiry |
Manus Aktteva Biopharma LLP | 08048250218Ext 800 | Ahmedabad, India | 655 | 58 | Inquiry |
Crystal Pharma | 08048600611 | Mumbai, India | 88 | 58 | Inquiry |
Supplier | Advantage |
---|---|
Medi Pharma Drug House | 58 |
A.J Chemicals | 58 |
CLEARSYNTH LABS LTD. | 58 |
Vitus Global Inc | 58 |
TCI Chemicals (India) Pvt. Ltd. | 58 |
Biopharmacule Speciality Chemicals P Ltd (India) | 58 |
Gansai International | 58 |
Dilipkumar & Co | 58 |
Manus Aktteva Biopharma LLP | 58 |
Crystal Pharma | 58 |
Related Qustion
- Q:Does Amprolium Hydrochloride have any effect on human health?
- A:Yes, it can cause adverse reactions such as contact dermatitis and asthma. Adverse reactions of anorexia or diarrhoea are rare....
- Dec 7,2023