PHALLACIDIN
- CAS No.
- 26645-35-2
- Chemical Name:
- PHALLACIDIN
- Synonyms
- PHALLICIDIN;PHALLACIDIN;Phallacidin
DISCONTINUED;CYCLO(ALA-2-MERCAPTO-TRP-4;phallacidin from amanita phalloides;Cyclo(Ala-
2- Mercapto- Trp- 4;5-DIHYDROXY-LEU-VAL-ERYTHRO-3-HYDROXY-D-ASP-CYS-CIS-4-HYDROXY-PRO);-3-hydroxy-d-alpha-aspartyl-l-cysteinyl-cis-4-hydroxy-l-prolyl)cyclic(2-6)-s;cyclic(l-alanyl-2-mercapto-l-tryptophyl-4,5-dihydroxy-l-leucyl-l-valyl-erythro;Cyclo[L-Ala-L-Trp2(1)-4,5-dihydroxy-L-Leu-L-Val-[(3S)-3-hydroxy-D-Asp-]-L-Cys(1)-L-c4Hyp-]
- CBNumber:
- CB6136097
- Molecular Formula:
- C37H50N8O13S
- Molecular Weight:
- 846.9
- MOL File:
- 26645-35-2.mol
- Modify Date:
- 2024/7/2 8:55:12
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS06 |
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---|---|---|---|---|---|---|---|---|---|---|
Signal word | Danger | |||||||||
Hazard statements | H300+H310+H330 | |||||||||
Precautionary statements | P260-P262-P264-P280-P302+P352+P310-P304+P340+P310 | |||||||||
Hazard Codes | T+ | |||||||||
Risk Statements | 26/27/28 | |||||||||
Safety Statements | 22-36/37/39-45 | |||||||||
RIDADR | 1544 | |||||||||
WGK Germany | 3 | |||||||||
RTECS | GT8943000 | |||||||||
HazardClass | 6.1(a) | |||||||||
PackingGroup | I | |||||||||
HS Code | 2934999090 | |||||||||
NFPA 704 |
|
PHALLACIDIN Chemical Properties,Uses,Production
Description
Phallacidin is a natural mycotoxin first isolated from the death cap mushroom, A. phalloides. It binds filamentous actin (F-actin) like phalloidin , but contains a carboxyl group for coupling reactions.
Uses
Toxin Phallacidin is a weak fluorescent bicyclic peptide probe in aquous solution, Which is isolated from Amanita phalloides mushroom and could be used for blocking F-actin staining by labeled phallotoxins, which promotes actin polymerization.
Definition
ChEBI: A homodetic bicyclic heptapeptide having a sulfide bridge.
Enzyme inhibitor
This cyclic heptapeptide toxin (FWfree-acid = 846.92 g/mol; CAS 26645-35-2) from the poisonous green fungus Amanita phalloides stabilizes actin filaments and inhibits actin filament depolymerization. NBD phallacidin is a high-affinity, filamentous actin probe consisting of rabbit actin that is conjugated by reacting its thiol group with 4-chloro-7- nitrobenzofurazan, a yellow-green fluorescent dye. NBD phallacidin (Excitation at 465 nm; Emission at 536 nm) selectively stains F-actin un a manner that is superior to antibody staining, preferably in fixed and permeabilized samples. See Phalloidin
PHALLACIDIN Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | Inquiry |
---|---|---|---|---|---|
CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
Aladdin Scientific | +1-+1(833)-552-7181 | United States | 57511 | 58 | Inquiry |
Shanghai Aladdin Bio-Chem Technology Co.,LTD | 400-400-6206333 18521732826 | China | 25014 | 65 | Inquiry |
TargetMol Chemicals Inc. | 15002134094 | China | 28118 | 58 | Inquiry |
Changzhou Xianglong Pharmaceutical Technology Co., LTD | 0519-88910898 18661161657 | China | 9998 | 58 | Inquiry |
Beijing Solarbio Science & Tecnology Co., Ltd. | 010-50973130 4009686088 | China | 29795 | 68 | Inquiry |
Cayman Chemical Company | (800) 364-9897 | United States | 6618 | 81 | Inquiry |
Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | China | 9708 | 58 | Inquiry |
Auonsi (Shanghai) Biology Technology Co., Ltd. | 400-1107768 15058188853 | China | 8555 | 58 | Inquiry |
ShangHai Anpel Co, Ltd. | 18501792038; 18501792038 | China | 9614 | 58 | Inquiry |