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Saxagliptin

Saxagliptin Structure
CAS No.
361442-04-8
Chemical Name:
Saxagliptin
Synonyms
Saxagliptin HCl;Onglyza;Saxagliptin API;Saxagliptin USP/EP/BP;CS-199;xagliptin;BMS 477118;Saxagliptin;Saxagliptin 15ND2;Saxagliptin, >=98%
CBNumber:
CB61856071
Molecular Formula:
C18H25N3O2
Molecular Weight:
315.41
MOL File:
361442-04-8.mol
MSDS File:
SDS
Modify Date:
2024/7/16 18:25:32
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Saxagliptin Properties

Melting point 103 - 107°C
Boiling point 548.7±35.0 °C(Predicted)
Density 1.35
Flash point 548.7℃
storage temp. 2-8°C
solubility DMSO (Slightly), Methanol (Sparingly)
pka 15.12±0.40(Predicted)
form Solid
color White to Off-White
Stability Temperature Sensitive

SAFETY

Risk and Safety Statements

Risk Statements  28-38-41-48
Safety Statements  24/25-26-28-36/37/39
RIDADR  3077
HS Code  29339900

Saxagliptin Chemical Properties,Uses,Production

Chemical Properties

White Solid
Saxagliptin

Definition

ChEBI: A monocarboxylic acid amide obtained by formal condensation of the carboxy group of (2S)-amino(3-hydroxyadamantan-1-yl)acetic acid with the amino group of (1S,3S,5S)-2-azabicyclo[3.1.0]hex ne-3-carbonitrile. Used in its monohydrate form for the treatment of Type II diabetes.

Clinical Use

Saxagliptin, previously identified as BMS-477118, is an oral hypoglycemic of the dipeptidyl peptidase-4 (DPP-4) inhibitor class developed by Bristol-Myers Squibb for the treatment of type 2 diabetes. DPP-IV is the primary enzyme responsible for degradation of incretins, such as glucagon-like peptide-1 (GLP-1), which is a hormone responsible for the glucose-dependent stimulation of insulin in humans. Inhibitors of DPP-IV serve as effective glucose regulators by increasing the endogenous concentration of GLP-1.

Saxagliptin Preparation Products And Raw materials

Raw materials

Preparation Products

Saxagliptin Suppliers

Global( 350)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
Apotex Pharmachem India Pvt Ltd +91-8022891034 +91-8022891000 Karnataka, India 109 58 Inquiry
Glenmark Pharmaceuticals Limited +912240189999 Maharashtra, India 93 58 Inquiry
Lee Pharma Ltd +91-9849085929 +91-9849085929 Hyderabad, India 42 58 Inquiry
Globela Industry Pvt Ltd +91-2616158000 +91-9998199919 Gujarat, India 98 58 Inquiry
LEE PHARMA LIMITED +91-40-23770338 New Delhi, India 35 58 Inquiry
Athos Chemicals 91-9998858909 Gujarat, India 315 58 Inquiry
KPS Chemicals & Pharmaceuticals 91--8469484608 Gujarat, India 240 58 Inquiry
Synthink Research Chemicals 09158051123 Pune, India 398 58 Inquiry
Oceanic Pharmachem Pvt. Ltd. 91-22-42128600 Maharashtra, India 2006 58 Inquiry
Avience chemicals and pharmaceuticals 91-7046079465 Gujarat, India 180 58 Inquiry
Supplier Advantage
Apotex Pharmachem India Pvt Ltd 58
Glenmark Pharmaceuticals Limited 58
Lee Pharma Ltd 58
Globela Industry Pvt Ltd 58
LEE PHARMA LIMITED 58
Athos Chemicals 58
KPS Chemicals & Pharmaceuticals 58
Synthink Research Chemicals 58
Oceanic Pharmachem Pvt. Ltd. 58
Avience chemicals and pharmaceuticals 58

Saxagliptin Spectrum

Saxagliptin(361442-04-8)1HNMR

361442-04-8(Saxagliptin)Related Search:

Dapagliflozin dimebolin Saxagliptin hydrate 2-Azabicyclo[3.1.0]hexane-2-carboxylic acid, 3-(aMinocarbonyl)-, 1,1-diMethylethyl ester, (1S,3R,5S)- Saxagliptin Impurity 6
Trelagliptin Pregabalin Ibrutinib Metformin Troglitazone
Sofosbuvir AZD 1480 ABT 737 Regorafenib Tideglusib
Ruxolitinib Pravastatin Saxagliptin
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(1S,3S,5S)-2-[(2S)-2-amino-2-(3-hydroxy-tricyclo[3.3.13,7]dec-1-yl)-1-oxoethyl]-2-azabicyclo-[3.1.0]hexane-3-carbonitrile BMS 477118 Saxagliptin (1S,3S,5S)-2-[(2S)-2-Amino-2-(3-hydroxytricyclo[3.3.1.13,7]dec-1-yl)acetyl]-2-azabicyclo[3.1.0]hexane-3-carbonitrile Saxagliptin(BMS 477118) Saxagliptin 15ND2 BMS477118;SAXAGLIPTIN (1S,3S,5S)-2-[(2S)-2-aMino-2-(3-hydroxyadaMantan-1-yl)acetyl]-2-azabicyclo[3.1.0]hexane-3-carbonitrile 2-Azabicyclo[3.1.0]hexane-3-carbonitrile, 2-[(2S)-2-amino-2-(3-hydroxytricyclo[3.3.1.13,7]dec-1-yl)acetyl]-, (1S,3S,5S)- Saxagliptin (1S,3S,5S)-2-[(2S)-2-Amino-2-(3-hydroxytricyclo[3.3.1.1(3,7)]dec-1-yl)acetyl]-2-azabicyclo[3.1.0]hexane-3-carbonitrile Saxagliptin, >=98% Saxagliptin Onglyza BMS 477118 Saxagliptin, 97%, selective and reversible DPP4 inhibitor CS-199 Saxagliptin-13C-d2 HCl Saxagliptin ? BMS 477118 ?Onglyza Saxagliptin , SAXAGLIPTIN [13C2,15N]-Saxagliptin xagliptin Salkeliptin impurity Saxagliptin 13C D2 HClQ: What is Saxagliptin 13C D2 HCl Q: What is the CAS Number of Saxagliptin 13C D2 HCl Saxagliptin-13C,d2 TFA SaltQ: What is Saxagliptin-13C,d2 TFA Salt Q: What is the CAS Number of Saxagliptin-13C,d2 TFA Salt SaxagliptinQ: What is Saxagliptin Q: What is the CAS Number of Saxagliptin Q: What is the storage condition of Saxagliptin Q: What are the applications of Saxagliptin Onglyza Saxagliptin HCl Saxagliptin API Saxagliptin USP/EP/BP 2-Azabicyclo[3.1.0]hexane-3-carbonitrile,2-[(2S)-amino(3-hydroxytricyclo[3.3.1.13,7]dec-1-yl)acetyl]-, (1S,3S,5S)- 361442-04-8 61442-04-8 Amines Chiral Reagents Heterocycles Intermediates & Fine Chemicals Inhibitors organic pharmaceutical Pharmaceuticals