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4-Methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]benzoic acid methyl ester

4-Methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]benzoic acid methyl ester Structure
CAS No.
917392-54-2
Chemical Name:
4-Methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]benzoic acid methyl ester
Synonyms
Nilotinib Impurity 44;NILOTINIB EP IMPURITY G;Vitamin B6 Impurity 103;917392-54-2;Nilotinib Impurity 12 (Nilotinib EP Impurity G); 4-Methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino;Nilotinib Hydrochloride Monohydrate EP Impurity G;methyl 4-methyl-3-[[4-(3-pyridyl)pyrimidin-2-yl]amino]benzoate;methyl 4-methyl-3-[[4-(3-pyridyl)pyrimidin-2-yl]amino]benzoa...;Methyl 4-Methyl-3-((4-(pyridin-3-yl)pyriMidin-2-yl)aMino)benzoate
CBNumber:
CB62490045
Molecular Formula:
C18H16N4O2
Molecular Weight:
320.35
MOL File:
917392-54-2.mol
Modify Date:
2024/4/25 13:42:50
Request For Quotation

4-Methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]benzoic acid methyl ester Properties

Melting point 148 - 150°C
Boiling point 538.6±60.0 °C(Predicted)
Density 1.258
storage temp. 2-8°C
solubility Chloroform (Slightly), DMSO (Slightly)
form Solid
pka 2.70±0.12(Predicted)
color Pale Yellow to Light Beige

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P280-P301+P312-P304+P340
HS Code  2916399090

4-Methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]benzoic acid methyl ester Chemical Properties,Uses,Production

Uses

Methyl 4-methyl-3-[[4-(pyridin-3-yl)pyrimidin-2-yl]amino]benzoate is an intermediate used in the synthesis of 4-Methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]benzamide (M326838), which is an impurity of Nilotinib (N465300), a possible agent in the treatment of chronic myelogenous leukemia.

4-Methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]benzoic acid methyl ester Preparation Products And Raw materials

Raw materials

Methyl 3-amino-4-methylbenzoate 3-[(aMinoiMinoMethyl)aMino]-4-Methylbenzoic acid Methyl ester Mononitrate 4-(3-Pyridyl)-2-chloropyrimidine Methyl 3-bromo-4-methylbenzoate METHYL 3-IODO-4-METHYLBENZOATE
3-Pyridylboronic acid 4-(Pyridin-3-yl)pyrimidin-2-amine 3-Acetylpyridine Methanol
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Preparation Products

4-Methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]benzoic acid Nilotinib

4-Methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]benzoic acid methyl ester Suppliers

Global( 127)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
Pratap Organics Pvt Ltd +91 9920018682 +91 9152015164 Maharashtra, India 122 58 Inquiry
Pratap Organics Pvt. Ltd. +91 (22) 2767-0445 New Delhi, India 80 50 Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6257 58 Inquiry
Pharmaffiliates Analytics and Synthetics P. Ltd +91-172-5066494 Haryana, India 6739 58 Inquiry
Henan Fengda Chemical Co., Ltd +86-371-86557731 +86-13613820652 China 20235 58 Inquiry
career henan chemical co +86-0371-86658258 +8613203830695 China 29858 58 Inquiry
Shanghai Yingrui Biopharma Co.,Ltd 21-33585366 CHINA 1319 58 Inquiry
CONIER CHEM AND PHARMA LIMITED +8618523575427 China 49732 58 Inquiry
SHANGHAI T&W PHARMACEUTICAL CO., LTD. +86-021-61551413 +8618813727289 China 5738 58 Inquiry
Dayang Chem (Hangzhou) Co.,Ltd. +86-0571-88938639 +8617705817739 China 52849 58 Inquiry
Supplier Advantage
Pratap Organics Pvt Ltd 58
Pratap Organics Pvt. Ltd. 50
CLEARSYNTH LABS LTD. 58
Pharmaffiliates Analytics and Synthetics P. Ltd 58
Henan Fengda Chemical Co., Ltd 58
career henan chemical co 58
Shanghai Yingrui Biopharma Co.,Ltd 58
CONIER CHEM AND PHARMA LIMITED 58
SHANGHAI T&W PHARMACEUTICAL CO., LTD. 58
Dayang Chem (Hangzhou) Co.,Ltd. 58

917392-54-2(4-Methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]benzoic acid methyl ester)Related Search:

NILOTINIB IMPURITY 11 4-Methyl-N-(3-(5-Methyl-1H-iMidazol-1-yl)-5-(trifluoroMethyl)phenyl)-3-((4-(pyridin-3-yl)pyriMidin-2-yl)aMino)benzaMide 3-(5-Methyl-1H-iMidazol-1-yl)-5-(trifluoroMethyl)benzenaMine 3-[(Aminoiminomethyl)amino]-4-methylbenzoic acid ethyl ester mononitrate 1H-IMidazole, 4-Methyl-1-[3-nitro-5-(trifluoroMethyl)phenyl]-
3-(4-Methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)benzonitrile 4-Methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]benzoic acid Benzenamine, 3-(2-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)- Methyl 3-amino-4-methylbenzoate Nilotinib Impurity 10
Nilotinib N-Oxide Nilotinib Impurity 7 Nilotinib genotoxic impurity 3 Nilotinib Impurity 1 Nilotinib Impurity 20
3-Amino-4-methylbenzoic acid Nilotinib Impurity 28 Nilotinib impurity 3
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4-Methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]benzoic acid methyl ester 4-Methyl-3-(4-pyridin-3-yl-pyriMidin-2-ylaMino)-benzoic acid Methyl ester Methyl 4-Methyl-3-((4-(pyridin-3-yl)pyriMidin-2-yl)aMino)benzoate, Methyl 4-Methyl-3-(4-(pyridin-3-yl)pyriMidin-2-ylaMino)benzoate Methyl 4-Methyl-3-((4-(pyridin-3-yl)pyriMidin-2-yl)aMino)benzoate Benzoicacid, 4-Methyl-3-[[4-(3-pyridinyl)-2-pyriMidinyl]aMino]-, Methyl ester methyl 4-methyl-3-[[4-(3-pyridyl)pyrimidin-2-yl]amino]benzoate NILOTINIB EP IMPURITY G methyl 4-methyl-3-[[4-(3-pyridyl)pyrimidin-2-yl]amino]benzoa... 917392-54-2 Nilotinib Hydrochloride Monohydrate EP Impurity G 4-Methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino Nilotinib Impurity 44 Vitamin B6 Impurity 103 Nilotinib Impurity 12 (Nilotinib EP Impurity G) 917392-54-2