4-Methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]benzoic acid methyl ester

CAS No.: 917392-54-2

Chemical Name:: 4-Methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]benzoic acid methyl ester

Synonyms: NILOTINIB EP IMPURITY G;917392-54-2;Nilotinib Impurity 12 (Nilotinib EP Impurity G);Nilotinib Hydrochloride Monohydrate EP Impurity G; 4-Methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino;methyl 4-methyl-3-[[4-(3-pyridyl)pyrimidin-2-yl]amino]benzoate;methyl 4-methyl-3-[[4-(3-pyridyl)pyrimidin-2-yl]amino]benzoa...;Methyl 4-Methyl-3-((4-(pyridin-3-yl)pyriMidin-2-yl)aMino)benzoate;4-Methyl-3-(4-pyridin-3-yl-pyriMidin-2-ylaMino)-benzoic acid Methyl ester;4-Methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]benzoic acid methyl ester

CBNumber:: CB62490045

Molecular Formula:: C18H16N4O2

Molecular Weight:: 320.35

MOL File:: 917392-54-2.mol

Modify Date:: 2024/4/25 13:42:50

Request For Quotation

4-Methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]benzoic acid methyl ester Properties

Melting point	148 - 150°C
Boiling point	538.6±60.0 °C(Predicted)
Density	1.258
storage temp.	2-8°C
solubility	Chloroform (Slightly), DMSO (Slightly)
form	Solid
pka	2.70±0.12(Predicted)
color	Pale Yellow to Light Beige

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302-H315-H319-H335
Precautionary statements	P280-P301+P312-P304+P340
HS Code	2916399090

4-Methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]benzoic acid methyl ester Chemical Properties,Uses,Production

Uses

Methyl 4-methyl-3-[[4-(pyridin-3-yl)pyrimidin-2-yl]amino]benzoate is an intermediate used in the synthesis of 4-Methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]benzamide (M326838), which is an impurity of Nilotinib (N465300), a possible agent in the treatment of chronic myelogenous leukemia.

4-Methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]benzoic acid methyl ester Preparation Products And Raw materials

Raw materials

Methyl 3-amino-4-methylbenzoate 3-[(aMinoiMinoMethyl)aMino]-4-Methylbenzoic acid Methyl ester Mononitrate 4-(3-Pyridyl)-2-chloropyrimidine Methyl 3-bromo-4-methylbenzoate METHYL 3-IODO-4-METHYLBENZOATE

3-Pyridylboronic acid 4-(Pyridin-3-yl)pyrimidin-2-amine 3-Acetylpyridine Methanol

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Preparation Products

4-Methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]benzoic acid Nilotinib

4-Methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]benzoic acid methyl ester Suppliers

Global( 113)Suppliers

Supplier	Tel	Country	ProdList	Advantage	Inquiry
GLP Pharma Standards	+91 9866074638	Hyderabad, India	1644	58	Inquiry
Pratap Organics Pvt Ltd	+91 9920018682 +91 9152015164	Maharashtra, India	122	58	Inquiry
Pratap Organics Pvt. Ltd.	+91 (22) 2767-0445	New Delhi, India	80	50	Inquiry
CLEARSYNTH LABS LTD.	+91-22-45045900	Hyderabad, India	6351	58	Inquiry
Pharmaffiliates Analytics and Synthetics P. Ltd	+91-172-5066494	Haryana, India	6773	58	Inquiry
Henan Fengda Chemical Co., Ltd	+86-371-86557731 +86-13613820652	China	20361	58	Inquiry
career henan chemical co	+86-0371-86658258 +8613203830695	China	29901	58	Inquiry
Chongqing Chemdad Co., Ltd	+86-023-6139-8061 +86-86-13650506873	China	39916	58	Inquiry
Shanghai Yingrui Biopharma Co.,Ltd	21-33585366	CHINA	1320	58	Inquiry
CONIER CHEM AND PHARMA LIMITED	+8618523575427	China	49391	58	Inquiry

Supplier	Advantage
GLP Pharma Standards	58
Pratap Organics Pvt Ltd	58
Pratap Organics Pvt. Ltd.	50
CLEARSYNTH LABS LTD.	58
Pharmaffiliates Analytics and Synthetics P. Ltd	58
Henan Fengda Chemical Co., Ltd	58
career henan chemical co	58
Chongqing Chemdad Co., Ltd	58
Shanghai Yingrui Biopharma Co.,Ltd	58
CONIER CHEM AND PHARMA LIMITED	58

917392-54-2(4-Methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]benzoic acid methyl ester)Related Search:

NILOTINIB IMPURITY 11 4-Methyl-N-(3-(5-Methyl-1H-iMidazol-1-yl)-5-(trifluoroMethyl)phenyl)-3-((4-(pyridin-3-yl)pyriMidin-2-yl)aMino)benzaMide 3-(5-Methyl-1H-iMidazol-1-yl)-5-(trifluoroMethyl)benzenaMine 3-[(Aminoiminomethyl)amino]-4-methylbenzoic acid ethyl ester mononitrate 1H-IMidazole, 4-Methyl-1-[3-nitro-5-(trifluoroMethyl)phenyl]-

3-(4-Methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)benzonitrile 4-Methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]benzoic acid Benzenamine, 3-(2-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)- Methyl 3-amino-4-methylbenzoate Nilotinib Impurity 10

Nilotinib N-Oxide Nilotinib Impurity 7 Nilotinib genotoxic impurity 3 Nilotinib Impurity 1 Nilotinib Impurity 20

3-Amino-4-methylbenzoic acid Nilotinib Impurity 28 Nilotinib impurity 3

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4-Methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]benzoic acid methyl ester 4-Methyl-3-(4-pyridin-3-yl-pyriMidin-2-ylaMino)-benzoic acid Methyl ester Methyl 4-Methyl-3-((4-(pyridin-3-yl)pyriMidin-2-yl)aMino)benzoate, Methyl 4-Methyl-3-(4-(pyridin-3-yl)pyriMidin-2-ylaMino)benzoate Methyl 4-Methyl-3-((4-(pyridin-3-yl)pyriMidin-2-yl)aMino)benzoate Benzoicacid, 4-Methyl-3-[[4-(3-pyridinyl)-2-pyriMidinyl]aMino]-, Methyl ester methyl 4-methyl-3-[[4-(3-pyridyl)pyrimidin-2-yl]amino]benzoate NILOTINIB EP IMPURITY G methyl 4-methyl-3-[[4-(3-pyridyl)pyrimidin-2-yl]amino]benzoa... Nilotinib Impurity 12 (Nilotinib EP Impurity G) 917392-54-2 Nilotinib Hydrochloride Monohydrate EP Impurity G 4-Methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino 917392-54-2