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Piroctone olamine

Piroctone olamine Structure
CAS No.
68890-66-4
Chemical Name:
Piroctone olamine
Synonyms
OCTOPIROX;OCTO;1-hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)pyridin-2(1H)-one;PIROCTONE OLEAMINE;LGB-PO;octopiroxolamine;PIROCTONE OLAMINE;Piorctone Olamine;PiroCLone olaMine;Pirotone Oleamine
CBNumber:
CB6433396
Molecular Formula:
C16H30N2O3
Molecular Weight:
298.43
MOL File:
68890-66-4.mol
Modify Date:
2024/8/4 16:55:17

Piroctone olamine Properties

Melting point 134.0 to 138.0 °C
Boiling point 135-235℃[at 101 325 Pa]
Density 1.1[at 20℃]
vapor pressure 0-0Pa at 20-25℃
storage temp. Inert atmosphere,2-8°C
solubility Chloroform (Slightly, Sonicated), Methanol (Slightly)
pka 5.9-7.4[at 20 ℃]
form Solid
color White to Off-White
Water Solubility 400-50000mg/L at 20-25℃
Merck 14,7502
InChI InChI=1S/C14H23NO2.C2H7NO/c1-10-6-12(15(17)13(16)8-10)7-11(2)9-14(3,4)5;3-1-2-4/h6,8,11,17H,7,9H2,1-5H3;4H,1-3H2
InChIKey BTSZTGGZJQFALU-UHFFFAOYSA-N
SMILES C(N)CO.C(C1=CC(C)=CC(=O)N1O)C(C)CC(C)(C)C
LogP 1.05-3.86 at 20-25℃
CAS DataBase Reference 68890-66-4(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS05
Signal word  Danger
Hazard statements  H315-H318-H412
Precautionary statements  P273-P280-P302+P352-P305+P351+P338+P310
WGK Germany  2
RTECS  UU7786150
HS Code  2933399090
NFPA 704
0
2 0

Piroctone olamine price More Price(4)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) PHR2187 Piroctone Olamine Pharmaceutical Secondary Standard; Certified Reference Material 68890-66-4 500MG ₹58119.43 2022-06-14 Buy
Sigma-Aldrich(India) 51872 Piroctone olamine analytical standard, PESTANAL? 68890-66-4 100MG ₹11084.8 2022-06-14 Buy
TCI Chemicals (India) P2178 Piroctone Olamine 68890-66-4 1G ₹7500 2022-05-26 Buy
TCI Chemicals (India) P2178 Piroctone Olamine 68890-66-4 5G ₹9800 2022-05-26 Buy
Product number Packaging Price Buy
PHR2187 500MG ₹58119.43 Buy
51872 100MG ₹11084.8 Buy
P2178 1G ₹7500 Buy
P2178 5G ₹9800 Buy

Piroctone olamine Chemical Properties,Uses,Production

Uses

Piroctone olamine is used in combination with other substances as a part of shampoo effectively reduced the amount of dandruff and, at the same time, provided hair conditioning advantages. Recently was shown, that piroctone olamine could induce apoptosis and possessed a significant in vivo effect against myeloma.

Definition

ChEBI: An organoammonium salt that is the ethanolamine salt of piroctone.

brand name

Octopirox (Hoechst AG, Germany).

Mechanism of action

Piroctone olamine, also known as Octopirox, is an antifungal and antibacterial agent commonly used in cosmetic and personal care products, such as shampoos, conditioners, and lotions. It works by inhibiting the growth of various microorganisms, including yeasts and fungi, by disrupting their cell membranes and interfering with their metabolism. Specifically, piroctone olamine targets the enzymes responsible for synthesizing the cell membrane of microorganisms, inhibiting their growth and causing their eventual death. It also has anti-inflammatory properties that help to reduce redness and itching on the scalp and skin.

Side effects

It should be kept in mind that shampoos with Piroctone Olamine should not be used more than twice a week, unlike other daily-use shampoos that don't have this ingredient. One of the biggest side effects of Piroctone Olamine is that it can cause irritation and itchiness on the head.

Piroctone olamine Preparation Products And Raw materials

Global( 510)Suppliers
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NEERU MENTHOL PRIVATE LIMITED +91-8884114465 +91-8884114465 Uttar Pradesh, India 44 58 Inquiry
KROMOZOME +91-91-9650900955 +91-09650900955 Maharashtra, India 71 58 Inquiry
Vision Drugs Pvt Ltd +91 9948045450 Telangana, India 65 58 Inquiry
PRODIGIOUS LIFE SCIENCES +91-9177472555 +91-9177472555 Hyderabad, India 236 58 Inquiry
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SHREENEEL CHEMICALS +91-9879551919 +91-9879551919 Gujarat, India 34 58 Inquiry
Gonane Pharma +91-9819380043 +91-9819380043 NaviMumbai, India 192 58 Inquiry
VINEET LABORATORIES LIMITED +91-9642200049 +91-9642200049 Telangana, India 69 58 Inquiry
Vineet Life Sciences Private Limited +91-9642200049 +91-9642200049 Telangana, India 7 58 Inquiry
2(1H)-Pyridinone,1-hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)-,compd.with2-aminoethanol(1:1) 4,4-trimethylpentyl)-1-hydroxy-4-methyl-6-(compd.with2-2(1h)-pyridinon octopiroxolamine 1-hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)-2(1h)-pyridinoncompd.with2-aminoethanol(1:1) Hydroxyl pyrazole ketones 1-Hydroxy-4-methyl-6(2,4,4-trimethylpentyl)2-pyridon monoethanolamine 1-Hydroxy-4-methyl-6-(2,4,4-trimethylpentyl) -one compound with 2-aminoethanol (1:1) Ethanolamine salt (1:1) 1-hydroxy-4-methyl-6(2,4,4-trimethylpentyl)2-pyridon monoethanolamine salt PIROCTONE OLAMINE Piroctone olamine (OCTO) 1-hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)pyridin-2(1H)-one, compound with 2-aminoethanol (1:1) Piorctone Olamine 1-HYDROXY-4-METHYL-6-(2,4,4-TRIMETHYLPENTYL)2(1H)-PYRIDONE. 1-Hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)pyridin-2(1H)-on, Verbindung mit 2-Aminoethanol (1:1) 1-hydroxy-4-Methyl-6-(2,4,4-triMethylpentyl)pyridin-2(1H)-one-2-aMinoethanol (1:1) Pyridine-aMino ethanol 1-hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)pyridin-2-one 1-Hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)-2(1H)-pyridone·2-aminoethanol 2-Aminoethanol/1-hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)-2(1H)-pyridone,(1:1) Piroctone Olamine (200 mg) 1-Hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)-2(1H)-pyridone ethanolammonium salt PiroCLone olaMine Piroctone olamine Solution, 100ppm PIROCTONE OLAMINE 98.0+% LGB-PO 4-methyl-1-oxido-6-(2,4,4-trimethylpentyl)-2-pyridinone Piroctone olamine/octopirox Piroctone Olamine > Piroctone ethanolamine 2(1H)-Pyridinone, 1-hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)-, compd.with 2-aminoethanol (1:1)OTHER CA INDEX NAMES:Ethanol, 2-amino-, compd. with1-hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)-2(1H)-pyridinone (1:1) 1-Hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)-2(1H)-pyridone Ethanolamine Sinobio Anti Dangdruff Piroctone Olamine Oct for Shampoo CAS?68890-66-4?Octopirox Piroctone Olamine (1544406) OCTOPIROX PIROCTONE OLEAMINE OCTO 1-hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)pyridin-2(1H)-one Jarguard OCT Piroctone Oleamine 1-Hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)pyridin-2(1H)-one 2-aminoethanol salt Pirotone Oleamine HYDROXYPYRIDINONE(OCT) Piroctone olamine analytical standard, ≥99% 1-HYDROXY-4-METHYL6-(2,4,4-TRI METHYL PHENYL)-2-PYRIDONE MONO ETHANOL AMINE(PIROCTONE OLAMINE) Piroctone Olamine (PO 1-hydroxy-4-methyl-6- (2,4,4-trimethylpentyl)pyridin-2-one (Piroctone olamine) Piroctone ethanolamine salt HYDROXYPYRIDINONE(OCT)/Piroctone olamine 1-Hydroxy-4-methy1-6(2,4,4-trimethylpentyl)-2-pyridone monoethanolamine 68890-66-4 68890-64-4 951-78-4 C14H23NO2C2H7NOC16H30N2O3 C14H23NO2C2H7NO C14H23NO2C2H7NOC16H30 bacteriostatic and fungistatic ARAMINE