Chlorphenesin carbamate
- CAS No.
- 886-74-8
- Chemical Name:
- Chlorphenesin carbamate
- Synonyms
- maolate;U-19646;Kalsont;rinlaxer;NSC 82943;Kolpicortin-sine;Chlorphensin carbamate;CHLORPHENESIN CARBAMATE;laChlorphenesin Carbamate;p-Chlorophenyl-α-glyceryl ether carbamate
- CBNumber:
- CB6493622
- Molecular Formula:
- C10H12ClNO4
- Molecular Weight:
- 245.66
- MOL File:
- 886-74-8.mol
- MSDS File:
- SDS
- Modify Date:
- 2023/4/23 13:52:06
| Melting point | 89-91° |
|---|---|
| Density | 1.3336 (rough estimate) |
| refractive index | 1.6000 (estimate) |
| storage temp. | -20°C, Inert atmosphere |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| form | Solid |
| color | White to Off-White |
| CAS DataBase Reference | 886-74-8(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Toxicity | LD50 orally in rats: 748 mg/kg; i.v. in mice: 239 mg/kg (Cass, Frederick) |
|---|
Chlorphenesin carbamate Chemical Properties,Uses,Production
Uses
'Muscle relaxant
Definition
ChEBI: The carbamate ester of the primary hydroxy group of chlorphenesin. A centrally acting skeletal muscle relaxant, it is used in the symptomatic treatment of painful muscle spasm.
General Description
Chlorphenesin carbamate,3-(p-chlorophenoxy)-1,2-propanediol 1-carbamate (Maolate),is the p-chloro substituted and 1-carbamate derivativeof the lead compound in the development of this group ofagents, mephenesin. Mephenesin is weakly active and shortlivedbecause of facile metabolism of the primary hydroxylgroup. Carbamylation of this group increases activity. p-Chlorination increases the lipophilicity and seals off thepara position from hydroxylation. Metabolism, still fairlyrapid, involves glucuronidation of the secondary hydroxylgroup. The biological half-life in humans is 3.5 hours.
Chlorphenesin carbamate Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| Unilab Company | +91-912228260263 +91-63917864522 | Tamil Nadu, India | 43 | 58 | Inquiry |
| Synthokem Labs Private Limited | +91-9966400646 +91-9966400646 | Hyderabad, India | 15 | 58 | Inquiry |
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
| Pharmaffiliates Analytics and Synthetics P. Ltd | +91-172-5066494 | Haryana, India | 6773 | 58 | Inquiry |
| OCEAN TRADING CORPORATION | +91(22) 24921669 | New Delhi, India | 6211 | 58 | Inquiry |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | United States | 19892 | 58 | Inquiry |
| Career Henan Chemica Co | +86-0371-86658258 +8613203830695 | China | 30250 | 58 | Inquiry |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 | China | 34571 | 58 | Inquiry |
| Xi'an MC Biotech, Co., Ltd. | 029-89275612 +8618991951683 | China | 2255 | 58 | Inquiry |
| Dayang Chem (Hangzhou) Co.,Ltd. | 571-88938639 +8617705817739 | China | 52861 | 58 | Inquiry |