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Verteporfin

Verteporfin Structure
CAS No.
129497-78-5
Chemical Name:
Verteporfin
Synonyms
BPD-MA;Visudyne;CL 318952;NSC6242;NSC 6242;NSC-6242;VERTEPIRFIN;Verteporfin;Verteprofin;Verteporfen
CBNumber:
CB6505794
Molecular Formula:
2C41H42N4O8
Molecular Weight:
1437.61
MOL File:
129497-78-5.mol
MSDS File:
SDS
Modify Date:
2024/4/19 13:11:00
Request For Quotation

Verteporfin Properties

storage temp. -20°C
solubility DMSO: soluble2mg/mL, clear (warmed)
form powder
color Black
Stability Stable for 2 years from date of purchsae as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
InChIKey YHNBVDZVUQFVLS-RDSGBMLISA-N

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P280-P305+P351+P338
WGK Germany  3
HS Code  2933997500

Verteporfin price More Price(2)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) SML0534 Verteporfin ≥94% (HPLC) 129497-78-5 5MG ₹12297.2 2022-06-14 Buy
Sigma-Aldrich(India) SML0534 Verteporfin ≥94% (HPLC) 129497-78-5 25MG ₹50076.45 2022-06-14 Buy
Product number Packaging Price Buy
SML0534 5MG ₹12297.2 Buy
SML0534 25MG ₹50076.45 Buy

Verteporfin Chemical Properties,Uses,Production

Description

Verteporfin was introduced in Switzerland as a second-generation photosensitizer for photodynamic therapy of wet age-related macular degeneration in patients with subfoveal choroidal neovascularisation. It is constituted of a mixture of two regioisomers resulting from nonselective monohydrolysis of the methyl tetraester. Upon irradiation with a lowenergy nonheat-generating laser light of 689nm wavelength, both regioisomeric benzoporphyrins are responsible for the local generation of singlet oxygen leading to free radical damage of neovascular endothelial cells in subfoveal lesions of patients with agerelated macular degeneration. The lipophilic drug is injected i.v. as a liposomal formulation in order to favor its uptake by plasma lipoproteins and distribution to cells with a high expression of low density lipoprotein receptors such as tumor and neovascular endothelial cells. Verteporfin is also being developed for the treatment of other eye diseases, nonmelanoma skin cancer and psoriasis.

Uses

Verteporfin is a photosensitizer that is used in photodynamic therapy (PDT). Verteporfin can accumulate in tumor tissues allowing for 30 to 150 minutes optimal PDT after intravenous administration.

Verteporfin Preparation Products And Raw materials

Raw materials

Preparation Products

Verteporfin Suppliers

Global( 191)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
BDR Pharmaceuticals International Pvt Ltd +91-2240560560 +91-7718884418 Maharashtra, India 206 58 Inquiry
A.J Chemicals 91-9810153283 New Delhi, India 6124 58 Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
Pharmaffiliates Analytics and Synthetics P. Ltd +91-172-5066494 Haryana, India 6773 58 Inquiry
ATK CHEMICAL COMPANY LIMITED +undefined-21-51877795 China 32760 60 Inquiry
Henan Tianfu Chemical Co.,Ltd. +86-0371-55170693 +86-19937530512 China 21675 55 Inquiry
Hangzhou FandaChem Co.,Ltd. 008657128800458; +8615858145714 China 9338 55 Inquiry
career henan chemical co +86-0371-86658258 +8613203830695 China 29900 58 Inquiry
BOC Sciences +1-631-485-4226 United States 19553 58 Inquiry
Chongqing Chemdad Co., Ltd +86-023-6139-8061 +86-86-13650506873 China 39916 58 Inquiry
Supplier Advantage
BDR Pharmaceuticals International Pvt Ltd 58
A.J Chemicals 58
CLEARSYNTH LABS LTD. 58
Pharmaffiliates Analytics and Synthetics P. Ltd 58
ATK CHEMICAL COMPANY LIMITED 60
Henan Tianfu Chemical Co.,Ltd. 55
Hangzhou FandaChem Co.,Ltd. 55
career henan chemical co 58
BOC Sciences 58
Chongqing Chemdad Co., Ltd 58

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Verteporfin Spectrum

Verteporfin(129497-78-5)1HNMR

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Verteporfin(DB00460) Verteprofin Verteporfin Verteporphin 24H,26H-Benzo[b]porphine-9,13-dipropanoic acid, 18-ethenyl-4,4a-dihydro-3,4-bis(methoxycarbonyl)-4a,8,14,19-tetramethyl-, monomethyl ester, (4R,4aS)-rel- VERTEPIRFIN 9-methyl (I)13-methyl (II)trans-(±)- 18-ethenyl- 4,4a-dihydro-3,4 -bis(methoxycarbonyl)- 4a,8,14,19-tetramethyl- 23H,25H-benzo[b]porphine- 9,13- dipropanoate (4R,4aS)-rel-18-ethenyl-4,4a-dihydro-3,4-bis(methoxycarbonyl)-4a,8,14,19-tetramethyl-24H,26H-Benzo[b]porphine-9,13-dipropanoic acid monomethyl ester 3-[(23S,24R)-14-Ethenyl-5-(3-methoxy-3-oxopropyl)-22,23-bis(methoxycarbonyl)-4,10,15,24-tetramethyl-25,26,27,28-tetraazahexacyclo[16.6.1.13,6.18,11.113,16.019,24]octacosa-1,3,5,7,9,11(27),12,14,16,18(25),19,21-dodecaen-9-yl]propanoic acid VERTEPORFIN (200 MG) trans-3,4-Dicarboxy-4,4a-dihydro-4a,8,14,19-tetramethyl-18-vinyl-23H,25H-benzo(b)porphine-9,13-dipropionic acid 3,4,9-trimethyl ester (4R,4aS)-18-Ethenyl-4,4a-dihydro-3,4-bis(methoxycarbonyl)-4a,8,14,19-tetramethyl-24H,26H-benzo[b]porphine-9,13-dipropanoic acid monomethyl ester Verteporfin (Visudyne) Verteporfin USP/EP/BP Verteporfin (DB-00460, CL-318952, BPD-MA, BpdMA) VerteporfinQ: What is Verteporfin Q: What is the CAS Number of Verteporfin Q: What is the storage condition of Verteporfin Q: What are the applications of Verteporfin Verteporfen Verteporfin (1711461) N-Diethylformamide NSC 6242 NSC6242 NSC-6242 Visudyne CL 318952 BPD-MA 23H,25H-Benzo[b]porphine-9,13-dipropanoic acid, 18-ethenyl-4,4a-dihydro-3,4-bis(methoxycarbonyl)-4a,8,14,19-tetramethyl-, monomethyl ester, trans- Verteporfin,inhibit,CL318952,CL-318952,Yes-associated protein,Autophagy,Apoptosis,Inhibitor,YAP Verteporfin (CL 318952) 129497-78-5 C41H42N4O8 Visudyne Inhibitors APIs