MIANSERIN

MIANSERIN Structure
CAS No.
24219-97-4
Chemical Name:
MIANSERIN
Synonyms
Depnon;Org-4360;Org-5859;MIANSERIN;MIANSERINE;(S)-Mianserine;(R)-Mianserine;Mianserin USP/EP/BP;Mianserin Impurity 14;MIANSERIN,1.0MG/MLINMETHANOL
CBNumber:
CB6679015
Molecular Formula:
C18H20N2
Molecular Weight:
264.36
MOL File:
24219-97-4.mol
MSDS File:
SDS
Modify Date:
2023/9/4 15:51:00

MIANSERIN Properties

Boiling point 397.6°C (rough estimate)
Density 1.0092 (rough estimate)
refractive index 1.5200 (estimate)
storage temp. Store at -20°C
solubility Soluble in DMSO
form Powder
pka pKa 7.5(H2O,t =20.0) (Uncertain)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302+H312+H332
RIDADR  3249
HazardClass  6.1(b)
PackingGroup  III

MIANSERIN Chemical Properties,Uses,Production

Uses

Serotonin receptor antagonist. Antidepressant

World Health Organization (WHO)

Mianserin, a serotonin antagonist with antidepressant and antihistaminic activity, was introduced in 1975 for the treatment of depressive illness. Its use has since been associated with cases of severe blood dyscrasias, particularly in elderly patients, including agranulocytosis, leucopenia and granulocytopenia. Several drug regulatory authorities have reacted by stipulating that blood counts should be monitored regularly during the first few months of treatment and that administration should be discontinued immediately should any signs possibly indicative of dyscrasia develop.

MIANSERIN Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 53)Suppliers
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Pharmaffiliates Analytics and Synthetics P. Ltd +91-172-5066494 Haryana, India 6773 58 Inquiry
career henan chemical co +86-0371-86658258 +8613203830695 China 29888 58 Inquiry
Chongqing Chemdad Co., Ltd +86-023-6139-8061 +86-86-13650506873 China 39916 58 Inquiry
TargetMol Chemicals Inc. +1-781-999-5354 +1-00000000000 United States 19892 58 Inquiry
Hefei TNJ Chemical Industry Co.,Ltd. +86-0551-65418671 +8618949823763 China 34571 58 Inquiry
Dideu Industries Group Limited +86-29-89586680 +86-15129568250 China 24200 58 Inquiry
AFINE CHEMICALS LIMITED +86-0571-85134551 China 15395 58 Inquiry
changzhou huayang technology co., ltd +8615250961469 China 9827 58 Inquiry
PT CHEM GROUP LIMITED China 35426 58 Inquiry
GIHI CHEMICALS CO.,LIMITED +8618058761490 China 50000 58 Inquiry
Dibenzoc,fpyrazino1,2-aazepine, 1,2,3,4,10,14b-hexahydro-2-methyl- MIANSERIN,1.0MG/MLINMETHANOL Dibenzo[c,f]pyrazino[1,2-a]azepine, 1,2,3,4,10,14b-hexahydro-2-methyl- (8CI, 9CI) MIANSERIN (1.0MG/ML METHANOL) (14bS)-1,2,3,4,10,14b-Hexahydro-2-methyldibenzo[c,f]pyrazino[1,2-a]azepine (14bS)-2-Methyl-1,2,3,4,10,14bα-hexahydrodibenzo[c,f]pyrazino[1,2-a]azepine (S)-Mianserine [14bS,(+)]-1,2,3,4,10,14bα-Hexahydro-2-methyldibenzo[c,f]pyrazino[1,2-a]azepine Org-4360 (14bR)-1,2,3,4,10,14b-Hexahydro-2-methyldibenzo[c,f]pyrazino[1,2-a]azepine (14bR)-2-Methyl-1,2,3,4,10,14bβ-hexahydrodibenzo[c,f]pyrazino[1,2-a]azepine (R)-Mianserine [14bR,(-)]-1,2,3,4,10,14bβ-Hexahydro-2-methyldibenzo[c,f]pyrazino[1,2-a]azepine Org-5859 2-Methyl-1,2,3,4,10,14b-hexahydrodibenzo[c,f]pyrazino[1,2-a]azepine 1,2,3,4,10,14b-hexahydro-2-methyldibenzo(c,f)pyrazino(1,2-a)azepine f)pyrazino(1,2-a)azepine,1,2,3,4,10,14b-hexahydro-2-methyl-dibenzo( MIANSERIN MIANSERINE Mianserin USP/EP/BP Depnon Mianserin Impurity 14 24219-97-4 Intermediates & Fine Chemicals Pharmaceuticals