PERPHENAZINE
- CAS No.
- 58-39-9
- Chemical Name:
- PERPHENAZINE
- Synonyms
- Trilafon;Perfenazina;Perphenazin;PZC;F-mon;sch3940;Fentazin;Emesinal;Decentan;Sch 3940
- CBNumber:
- CB6687009
- Molecular Formula:
- C21H26ClN3OS
- Molecular Weight:
- 403.97
- MOL File:
- 58-39-9.mol
- Modify Date:
- 2024/7/2 8:55:14
Melting point | 95-98?C |
---|---|
Boiling point | bp0.15 214-218°; bp1 278-281° |
Density | 1.253 |
refractive index | 1.6100 (estimate) |
storage temp. | 2-8°C |
solubility | Practically insoluble in water, freely soluble in methylene chloride, soluble in ethanol (96 per cent). It dissolves in dilute solutions of hydrochloric acid. |
form | Solid |
pka | pKa 7.8(H2O,t =24±1) (Uncertain) |
color | White |
Water Solubility | 28.28mg/L(24 ºC) |
Merck | 14,7183 |
Stability | Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months. |
CAS DataBase Reference | 58-39-9(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS07 |
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Signal word | Warning | |||||||||
Hazard statements | H302-H317 | |||||||||
Precautionary statements | P261-P264-P270-P280-P301+P312-P302+P352 | |||||||||
Hazard Codes | Xn | |||||||||
Risk Statements | 22-43 | |||||||||
Safety Statements | 28-36/37/39-45 | |||||||||
RIDADR | UN 2811 6.1 / PGII | |||||||||
WGK Germany | 3 | |||||||||
RTECS | TL7175000 | |||||||||
HS Code | 29349990 | |||||||||
Toxicity | LD50 oral in rat: 318mg/kg | |||||||||
NFPA 704 |
|
PERPHENAZINE price More Price(6)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich(India) | P6402 | Perphenazine | 58-39-9 | 1G | ₹8270.3 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | PHR3079 | Perphenazine pharmaceutical secondary standard, certified reference material | 58-39-9 | 500MG | ₹23241.28 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | P6402 | Perphenazine | 58-39-9 | 5G | ₹12546.18 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | P-130 | Perphenazine solution 1?mg/mL in methanol (), certified reference material, ampule of 1?mL, Cerilliant? | 58-39-9 | 1ML | ₹8857.8 | 2022-06-14 | Buy |
TCI Chemicals (India) | P1970 | Perphenazine | 58-39-9 | 5G | ₹8700 | 2022-05-26 | Buy |
PERPHENAZINE Chemical Properties,Uses,Production
Chemical Properties
Off-White to Pale Yellow Solid
Uses
D2 dopamine receptor antagonist; α-adrenergic receptor antagonist and σ-receptor agonist; phenothiazine antipsychotic. Inhibits glutamate dehydrogenase in vitro. Antipsychotic.
Definition
ChEBI: A phenothiazine derivative in which the phenothiazine tricycle carries a chloro substituent at the 2-position and a 3-[4-(2-hydroxyethyl)piperazin-1-yl]propyl group at N-10.
General Description
Perphenazine, 4-[3-(2-chlorophenothiazine-10-yl)propyl]piperazineethanol; 2-chloro-10-[3-[4-(2-hydroxyethyl)piperazinyl]propyl]phenothiazine(Trilafon), is an effective antipsychotic and antiemetic.
Safety Profile
Poison by ingestion, intravenous, subcutaneous, intraperitoneal, and intramuscular routes. Human systemic effects by intramuscular route: muscle spasms. Experimental teratogenic and reproductive effects. Human mutation data reported. When heated to decomposition it emits very toxic fumes of SOx, NOx, and cl-.
PERPHENAZINE Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | Inquiry |
---|---|---|---|---|---|
Apicore Pharmaceuticals Pvt Ltd | +91-2662267177 +91-2662267166 | Gujarat, India | 181 | 58 | Inquiry |
aistrifarma | +91-6374274350 +91-7708086868 | Tamil Nadu, India | 15 | 58 | Inquiry |
Clearsynth Labs | 91-22-45045900 | Maharashtra, India | 3889 | 58 | Inquiry |
CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
TCI Chemicals (India) Pvt. Ltd. | 1800 425 7889 | New Delhi, India | 6778 | 58 | Inquiry |
Pharmaffiliates Analytics and Synthetics P. Ltd | +91-172-5066494 | Haryana, India | 6773 | 58 | Inquiry |
Omcham Labs | 08048372728Ext 857 | Gujarat, India | 90 | 58 | Inquiry |
Globofarm International Private Limited | 91-22-49716506 | Maharashtra, India | 188 | 58 | Inquiry |
Pharma Affiliates | 172-5066494 | Haryana, India | 6761 | 58 | Inquiry |
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