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Prochlorperazine

Prochlorperazine Structure
CAS No.
58-38-8
Chemical Name:
Prochlorperazine
Synonyms
Compazine;PERPHENAZINE BASE;rp6140;6140rp;Nipodal;RP-6140;skf4657;Temetid;6140 RP;Emelent
CBNumber:
CB7352500
Molecular Formula:
C20H24ClN3S
Molecular Weight:
373.94
MOL File:
58-38-8.mol
MSDS File:
SDS
Modify Date:
2023/6/8 13:53:37

Prochlorperazine Properties

Melting point 228 °C
Boiling point 260-275 °C(Press: 2 Torr)
Density 1.1679 (rough estimate)
refractive index 1.6000 (estimate)
storage temp. Refrigerator
solubility Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
form Solid
pka pKa 8.1(H2O,t =24±1,I undefined) (Uncertain)
color White to Yellow
Water Solubility 14.96mg/L(24 ºC)
BCS Class 2
CAS DataBase Reference 58-38-8(CAS DataBase Reference)
NIST Chemistry Reference Prochlorperazine(58-38-8)

SAFETY

Risk and Safety Statements

Toxicity LD50 oral in rat: 1800mg/kg

Prochlorperazine Chemical Properties,Uses,Production

Uses

Prochlorperazine is antiemetic, antipsychotic; used in treatment of vertigo.

Definition

ChEBI: A member of the class of phenothiazines that is 10H-phenothiazine having a chloro substituent at the 2-position and a 3-(4-methylpiperazin-1-yl)propyl group at the N-10 position.

Safety Profile

Poison by ingestion, subcutaneous, intravenous, and intraperitoneal routes. Experimental teratogenic and reproductive effects. Human systemic effects by ingestion: headache, blood pressure elevation. Implicated in aplastic anemia. When heated to decomposition it emits very toxic fumes of SOx, NOx, and Cl-.

Prochlorperazine Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 95)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
Ralington Pharma +91-7948911722 +91-9687771722 Gujarat, India 1350 58 Inquiry
Biophore India Pharmaceuticals Pvt Ltd +91-9100031592 +91-9030907714 Telangana, India 134 58 Inquiry
BIOPHORE INDIA PHARMACEUTICALS PVT LTD +91-4047474545 New Delhi, India 105 58 Inquiry
SynZeal Research Pvt Ltd +1 226-802-2078 Gujarat, India 6522 58 Inquiry
Pharmaffiliates Analytics and Synthetics P. Ltd +91-172-5066494 Haryana, India 6773 58 Inquiry
Vcare Medicines 08046035803 Mumbai, India 114 58 Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
CONIER CHEM AND PHARMA LIMITED +8618523575427 China 49391 58 Inquiry
Neostar United (Changzhou) Industrial Co., Ltd. +86-519-519-85557386 China 12210 58 Inquiry
Career Henan Chemica Co +86-0371-86658258 +8613203830695 China 30253 58 Inquiry
n-(gamma-(4’-methylpiperazinyl-1’)propyl)-3-chlorophenothiazine N-(gamma-(4'-Methylpiperazinyl-1')propyl)-3-chlorophenothiazine n-[gamma-(4’-methylpiperazinyl-1’)propyl]-3-chlorophenothiazine Nipodal Phenothiazine, 2-chloro-10-[3-(1-methyl-4-piperazinyl)propyl]- Chloromeprazine 3-Chloro-10-chlorperazine 10-[3-(4-Methylpiperazino)propyl]-2-chloro-10H-phenothiazine Prochlorperazine Base Phenothiazine, 2-chloro-10-[3-(4-methyl-1-piperazinyl)propyl]- Prochloroperazine Prochlorpemazine Prochlorperazin prochlorpermazine Prochlorpromazine Procloperazine Proclorperazine rp6140 RP-6140 SKF 4657 skf4657 Stemetil Tementil Temetid PROCHLORPERAZINE 2-chloro-10-(3-(4-methylpiperazin-1-yl)propyl)phenothiazine Bayer A 17 10H-PHENOTHIAZINE, 2-CHLORO-10-[3-(4-METHYL-1-PIPERAZINYL)PROPYL]-, (Z)-2-BUTENEDIOATE 10H-Phenothiazine, 2-chloro-10-[3-(4-methyl-1-piperazinyl)propyl]- 2-Chloro-10-(3-(1-methyl-4-piperazinyl)-propyl)-phenothiazine 2-chloro-10-(3-(4-methyl-1-piperazinyl)propyl)-10h-phenothiazin 2-chloro-10-(3-(4-methyl-1-piperazinyl)propyl)-phenothiazin 2-Chloro-10-(3-(4-methyl-1-piperazinyl)propyl)phenothiazine 2-Chloro-10-[3-(4-methyl-1-piperazinyl)propyl]-10H-phenothiazine 3-Chloro-10-(3-(1-methyl-4-piperazinyl)propyl)phenothiazine 3-chloro-10-[3-(4-methyl-1-piperazinyl)propyl]phenothiazine 6140 R.P. 6140 RP 6140rp Bayer A 173 bayera173 Capazine Chlormeprazine Chloro-3 (N-methylpiperazinyl-3 propyl)-10 phenothiazine chloro-3(n-methylpiperazinyl-3propyl)-10phenothiazine chloro-3(n-methylpiperazinyl-3propyl)-10phenothiazine(french) Chlorperazine Emelent Eskatrol Kronocin Meterazin Meterazine Prochlorperazine USP/EP/BP Prochlorperazine EP Compazine PERPHENAZINE BASE Praziquantel Impurity 7-d11 58-38-8