3-Methyl-2-butanone
- CAS No.
- 563-80-4
- Chemical Name:
- 3-Methyl-2-butanone
- Synonyms
- 3-Methylbutan-2-one;METHYL ISOPROPYL KETONE;MIPK;ISOPROPYL METHYL KETONE;3-methyl-butan-2-one;2-METHYL-3-BUTANONE;3-Methylbutanone;2-Butanone,3-methyl-;-2-butanone;iso-C3H7COCH3
- CBNumber:
- CB2270896
- Molecular Formula:
- C5H10O
- Molecular Weight:
- 86.13
- MOL File:
- 563-80-4.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/8/8 18:06:34
| Melting point | -92 °C (lit.) |
|---|---|
| Boiling point | 94-95 °C (lit.) |
| Density | 0.805 g/mL at 25 °C (lit.) |
| vapor pressure | 53.33 hPa (19.9 °C) |
| refractive index |
n |
| Flash point | 6 °C |
| storage temp. | Store below +30°C. |
| solubility | water: soluble8.21g/L at 20°C |
| form | Liquid |
| color | Clear colorless |
| Odor | at 0.10?%?in?dipropylene glycol. camphor |
| explosive limit | 1.5-9%(V) |
| Odor Threshold | 0.5ppm |
| Water Solubility | 6 g/L (20 ºC) |
| Merck | 14,6090 |
| BRN | 1071238 |
| Exposure limits | TLV-TWA 700 mg/m3 (200 ppm); STEL 875 mg/m3 (250 ppm) (ACGIH). |
| Dielectric constant | 16.57 |
| InChIKey | SYBYTAAJFKOIEJ-UHFFFAOYSA-N |
| LogP | 2.29 at 20℃ |
| CAS DataBase Reference | 563-80-4(CAS DataBase Reference) |
| NIST Chemistry Reference | 2-Butanone, 3-methyl-(563-80-4) |
| EPA Substance Registry System | Methyl isopropyl ketone (563-80-4) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS02 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H225 | |||||||||
| Precautionary statements | P210-P233-P240-P241-P242-P243 | |||||||||
| Hazard Codes | F | |||||||||
| Risk Statements | 11-67 | |||||||||
| Safety Statements | 9-16-33 | |||||||||
| OEB | A | |||||||||
| OEL | TWA: 200 ppm (705 mg/m3) | |||||||||
| RIDADR | UN 2397 3/PG 2 | |||||||||
| WGK Germany | 1 | |||||||||
| RTECS | EL9100000 | |||||||||
| Autoignition Temperature | 475 °C | |||||||||
| Hazard Note | Highly Flammable | |||||||||
| TSCA | Yes | |||||||||
| HazardClass | 3 | |||||||||
| PackingGroup | II | |||||||||
| HS Code | 29141990 | |||||||||
| Toxicity | LD50 orally in male mice: 29.86 mmol/kg (Tanii) | |||||||||
| NFPA 704 |
|
3-Methyl-2-butanone price More Price(8)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | 8.05966 | Isopropyl methyl ketone for synthesis | 563-80-4 | 250ML | ₹4400.01 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 8.05966 | Isopropyl methyl ketone for synthesis | 563-80-4 | 1L | ₹8170 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 59600 | 3-Methyl-2-butanone puriss., ≥98.5% (GC) | 563-80-4 | 100ML | ₹3777.93 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 59600 | 3-Methyl-2-butanone puriss., ≥98.5% (GC) | 563-80-4 | 1L | ₹11387.9 | 2022-06-14 | Buy |
| TCI Chemicals (India) | M0173 | 3-Methyl-2-butanone min. 99.0 % | 563-80-4 | 25ML | ₹1800 | 2022-05-26 | Buy |
3-Methyl-2-butanone Chemical Properties,Uses,Production
Chemical Properties
CLEAR COLOURLESS LIQUID
Chemical Properties
MIPK is a colorless liquid with an acetonelike odor. 3-Methyl-2-butanone is a colorless liquid with a characteristic ketone odor.3-Methyl-2-butanone undergoes condensation reactions preferentially at the methyl group. The tertiary carbon atom is easily oxidized and the resulting hydroperoxide (mp 26 – 27℃) can be produced by base-catalyzed air oxidation.
Uses
3-Methyl-2-butanone is used for synthesis of heterocyclic compounds and important intermediate of medicine. It is used as an industrial solvent.
Uses
Solvent for nitrocellulose lacquers. 3-Methyl-2-butanone is employed predominantly as an intermediate for the production of pharmaceuticals, herbicides, and dye precursors. It is also used in the synthesis of rubber auxiliaries and for the selective extraction of rare earth elements.
Preparation
3-Methyl-2-butanone is produced by oxidation of Methyl-iso-propylcarbinol (2-Methyl-3-butanol).
General Description
A colorless liquid with a pleasant odor. Flash point below 70°F. Less dense than water. May be toxic by inhalation and skin absorption. Used as a solvent.
Air & Water Reactions
Highly flammable. Soluble in water.
Reactivity Profile
Ketones, such as 3-Methyl-2-butanone, are reactive with many acids and bases liberating heat and flammable gases (e.g., H2). The amount of heat may be sufficient to start a fire in the unreacted portion of the ketone. Ketones react with reducing agents such as hydrides, alkali metals, and nitrides to produce flammable gas (H2) and heat. Ketones are incompatible with isocyanates, aldehydes, cyanides, peroxides, and anhydrides. They react violently with aldehydes, HNO3, HNO3 + H2O2, and HClO4.
Hazard
Toxic material. Embryo/fetal damage andneonatal toxicity.
Health Hazard
Irritating to the eyes, nose, throat, upper respiratory tract, and skin.
Fire Hazard
Special Hazards of Combustion Products: Acrid smoke and fumes
Safety Profile
Poison by ingestion. Mildly toxic by inhalation and skin contact. Mutation data reported. A skin and eye irritant. Flammable when exposed to heat or flame; can react vigorously with oxidizing materials. When heated to decomposition it emits acrid smoke and irritating fumes.
Potential Exposure
This ketone is used as a solvent for nitrocellulose lacquers.
Shipping
UN23973-Methylbutan-2-one, Hazard Class: 3; Labels: 3-Flammable liquid.
Purification Methods
Reflux the ketone with a little KMnO4. Fractionate it through a spinning-band column, dry with CaSO4 and distil it. [Beilstein 1 IV 3287.]
Incompatibilities
Vapors may form explosive mixture with air. Ketones are incompatible with oxidizers (chlorates, nitrates, peroxides, permanganates, perchlorates, chlorine, bromine, fluorine, etc.); contact may cause fires or explosions. Keep away from alkaline materials, strong bases, strong acids, oxoacids, epoxides, nitrated amines, azo, diazo, azido compounds, carbamates, organic cyanates
Waste Disposal
Dissolve or mix the material with a combustible solvent and burn in a chemical incinerator equipped with an afterburner and scrubber. All federal, state, and local environmental regulations must be observed.
3-Methyl-2-butanone Preparation Products And Raw materials
Raw materials
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