ChemicalBook > Product Catalog >API >Nervous system drugs >Antipsychotics >Thioridazine

Thioridazine

Thioridazine Structure
CAS No.
50-52-2
Chemical Name:
Thioridazine
Synonyms
tp21;TP-21;Thioril;Meleril;Sonapax;Mallorol;Malloryl;Mellaril;Mellarit;Melleril
CBNumber:
CB6763367
Molecular Formula:
C21H26N2S2
Molecular Weight:
370.57
MOL File:
50-52-2.mol
MSDS File:
SDS
Modify Date:
2023/4/23 13:52:06

Thioridazine Properties

Melting point 72-74°
Boiling point bp0.02 230°
Density 1.1693 (rough estimate)
refractive index 1.5800 (estimate)
Flash point 9℃
storage temp. Sealed in dry,Room Temperature
solubility Practically insoluble in water, very soluble in methylene chloride, freely soluble in methanol, soluble in ethanol (96 per cent).
pka 9.5(at 25℃)
Water Solubility 1.113mg/L(22.5 ºC)
NIST Chemistry Reference 10H-Phenothiazine, 10-[2-(1-methyl-2-piperidyl)ethyl]-2-methylthio-(50-52-2)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P264-P270-P301+P312-P501
Hazard Codes  F,T
Risk Statements  11-23/24/25-39/23/24/25-52/53
Safety Statements  16-36/37-45-61
RIDADR  UN1230 - class 3 - PG 2 - Methanol, solution
WGK Germany  1
HS Code  2934302300
Toxicity LD50 orally in rats: 995 ±39 mg/kg (Goldenthal)

Thioridazine price More Price(1)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) T-905 Thioridazine solution 1.0?mg/mL in methanol, ampule of 1?mL, certified reference material, Cerilliant? 50-52-2 1ML ₹8179.5 2022-06-14 Buy
Product number Packaging Price Buy
T-905 1ML ₹8179.5 Buy

Thioridazine Chemical Properties,Uses,Production

Description

An antipsychotic drug of the phenothiazine class. It is of particular interest because of its “atypical” properties, some of which may be due to its extensive bioconversion to active metabolites. The therapeutic and side effects of thioridazine and its metabolites involve blockade of brain dopamine receptors, but also actions mediated via blockage of muscarininc cholinergic and α-adrenergic receptors.

Chemical Properties

Colorless crystals. Soluble in water and alcohol.

Uses

In terms of antipsychotic activity, thioridazine is inferior to aminazine. It is most effective in mental and emotional disorders accompanied by fear, stress, and excitement. It is prescribed for various forms of schizophrenia, psychosis, and neurosis.

Definition

ChEBI: A phenothiazine derivative having a methylsulfanyl subsitituent at the 2-position and a (1-methylpiperidin-2-yl)ethyl] group at the N-10 position.

Thioridazine Preparation Products And Raw materials

Raw materials

Preparation Products

Thioridazine Suppliers

Global( 71)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
SynZeal Research Pvt Ltd +1 226-802-2078 Gujarat, India 6522 58 Inquiry
Pharmaffiliates Analytics and Synthetics P. Ltd +91-172-5066494 Haryana, India 6773 58 Inquiry
SHANDONG ZHI SHANG CHEMICAL CO.LTD +86 18953170293 China 2931 58 Inquiry
CONIER CHEM AND PHARMA LIMITED +8618523575427 China 49392 58 Inquiry
career henan chemical co +86-0371-86658258 +8613203830695 China 29825 58 Inquiry
Dideu Industries Group Limited +86-29-89586680 +86-15129568250 China 24200 58 Inquiry
AFINE CHEMICALS LIMITED +86-0571-85134551 China 15395 58 Inquiry
Dayang Chem (Hangzhou) Co.,Ltd. 571-88938639 +8617705817739 China 52861 58 Inquiry
GIHI CHEMICALS CO.,LIMITED +8618058761490 China 50000 58 Inquiry
Shanghai Likang New Materials Co., Limited +86-16631818819 +86-17736933208 China 9311 58 Inquiry
THIORIDAZINE 10-[2-(1-Methyl-2-piperidyl)]-2-[methylthio] phenothiazine THIORIDAZINE,1.0MG/MLINMETHANOL 10-[2-(1-ethyl-2-piperidyl)ethyl]-2-(methylthio)phenothiazine 10H-Phenothiazine, 10-[2-(1-methyl-2-piperidinyl)ethyl]-2-(methylthio)- (9CI) dl-Thioridazine Phenothiazine, 10-[2-(1-methyl-2-piperidyl)ethyl]-2-(methylthio)- (6CI, 8CI) Thioril 10-[2-(1-methylpiperidin-2-yl)ethyl]-2-methylsulfanylphenothiazine 10-[2-(1-methylpiperidin-2-yl)ethyl]-2-methylsulfanyl-phenothiazine THIORIDAZINE BASE Thioridazine (200 mg) 10-((1-methyl-2-piperidyl)ethyl)-2-(methylthio)-phenothiazin 10-(2-(1-methyl-2-piperidinyl)ethyl)-2-(methylthio)-10h-phenothiazin 10-(2-(1-methyl-2-piperidyl)ethyl)-2-(methylthio)-phenothiazin 10-(2-(1-Methyl-2-piperidyl)ethyl)-2-(methylthio)phenothiazine 10-[2-(1-Methyl-2-piperdiyl)ethyl]-2-(methylthio)phenothiazine 10-[2-(1-Methyl-2-piperidinyl)ethyl]-2-(methylsulfanyl)-10H-phenothiazine 10H-Phenothiazine, 10-[2-(1-methyl-2-piperidinyl)ethyl]-2-(methylthio)- 2-Methylmercapto-10-(2-(N-methyl-2-piperidyl)ethyl)phenothiazine 10-[2-(1-methyl-2-piperidyl)ethyl]-2-methylthio-10h-phenothiazine Thioridazine solution 10-(2-(1-Methylpiperidin-2-yl)ethyl)-2-(methylthio)-10H-phenothiazine 10-(2-(1-Methylpiperidin-2-yl) 2-methylmercapto-10-(2-n-methyl-2-piperidyl)ethyl)phenothiazine 3-methylmercapto-n-[2’-(n-methyl-2-piperidyl)ethyl]phenothiazine Mallorol Malloryl Meleril Mellaril Mellaril-S Mellarit Mellerets Mellerette Melleretten Melleril melleril(liquid) Phenothiazine, 10-((1-methyl-2-piperidyl)ethyl)-2-(methylthio)- Phenothiazine, 10-[2-(1-methyl-2-piperidyl)ethyl]-2-(methylthio)- Sonapax Thioridazin Thioridazine, prolongatum thioridazineprolongatum tp21 TP-21 Thioridazine CRS Thioridazine for system suitability CRS Thioridazine USP/EP/BP Thioridazine DISCONTINUED. Please see T368800. Thioridazine (1662504) hioridazine 50-52-2 C21H26N2S2 Thioridazine