ChemicalBook > Product Catalog >API >Nervous system drugs >Antipsychotics >Thioridazine hydrochloride
Thioridazine hydrochloride
- CAS No.
- 130-61-0
- Chemical Name:
- Thioridazine hydrochloride
- Synonyms
- L-714;Ridazin;Orsanil;usafsz-3;USAF SZ-B;Stalleril;NSC 186060;Novoridazine;465 (Maleate);ThioridazinHCl
- CBNumber:
- CB4256836
- Molecular Formula:
- C21H27ClN2S2
- Molecular Weight:
- 407.04
- MOL File:
- 130-61-0.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/11/17 16:00:36
| Melting point | 158-1600C |
|---|---|
| Boiling point | 230°C (rough estimate) |
| Density | 1.1227 (rough estimate) |
| refractive index | 1.5610 (estimate) |
| storage temp. | 2-8°C |
| solubility | H2O: soluble250 mg plus 5 ml of solvent, clear, colorless to faintly yellow |
| form | Off-white solid |
| color | White to Almost white |
| Water Solubility | Soluble in water (75 mM), DMSO (100 mM), chloroform, ethanol, and methanol. |
| Sensitive | Light Sensitive & Hygroscopic |
| λmax | 317nm(EtOH)(lit.) |
| Merck | 14,9359 |
| InChIKey | NZFNXWQNBYZDAQ-UHFFFAOYSA-N |
| CAS DataBase Reference | 130-61-0(CAS DataBase Reference) |
| NIST Chemistry Reference | Thioridazine hydrochloride(130-61-0) |
| EPA Substance Registry System | 10H-Phenothiazine, 10-[2-(1-methyl-2-piperidinyl)ethyl]-2-(methylthio)-, monohydrochloride (130-61-0) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302 | |||||||||
| Precautionary statements | P264-P270-P301+P312-P501 | |||||||||
| Hazard Codes | Xn,N | |||||||||
| Risk Statements | 22-36/37/38-50/53 | |||||||||
| Safety Statements | 26-36-60-61 | |||||||||
| RIDADR | UN 3077 9/PG 3 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | SP2275000 | |||||||||
| HazardClass | 9 | |||||||||
| HS Code | 2934302300 | |||||||||
| NFPA 704 |
|
Thioridazine hydrochloride price More Price(6)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | T9025 | Thioridazine hydrochloride ≥99% | 130-61-0 | 5G | ₹10879.13 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | T9025 | Thioridazine hydrochloride ≥99% | 130-61-0 | 25G | ₹36534.38 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | PHR3143 | Thioridazine Hydrochloride pharmaceutical secondary standard, certified reference material | 130-61-0 | 500MG | ₹16724.63 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 324387 | Dopamine Receptor Antagonist II, Thioridazine, HCl - CAS 130-61-0 - Calbiochem The Dopamine Receptor Antagonist II, Thioridazine, HCl, also referenced under CAS 130-61-0, controls the biological activity of Dopamine Receptor. Thi | 130-61-0 | 2G | ₹5560 | 2022-06-14 | Buy |
| TCI Chemicals (India) | T3102 | Thioridazine Hydrochloride | 130-61-0 | 5G | ₹6200 | 2022-05-26 | Buy |
Thioridazine hydrochloride Chemical Properties,Uses,Production
Chemical Properties
Pale Yellow Solid
Uses
Thioridazine hydrochloride has been used as an intercalating agent for analyzing the integrity of double-stranded DNA (dsDNA) using square-wave voltammetry (SWV) techniques. Thioridazine hydrochloride has also been used as a positive control for the inhibition of hepatic enzyme cytochrome P4502D6 (CYP2D6) in human liver microsomes.
General Description
Thioridazine hydrochloride,10-[2-(1-methyl-2-piperidyl)ethyl]-2-(methylthio)phenothiazine monohydrochloride (Mellaril), is amember of the piperidine subgroup of the phenothiazines.The drug has a relatively low tendency to produce EPS. Thedrug has high anticholinergic activity, and this activity in thestriatum, counterbalancing a striatal DA block, may be responsiblefor the low EPS. It also has been suggested thatthere may be increased DA receptor selectivity, which may be responsible. The drug has sedative and hypotensive activityin common with chlorpromazine and less antiemeticactivity. At high doses, pigmentary retinopathy has been observed.Its major metabolites include N-demethylated, ringhydroxylated,and S-oxidized products. Thioridazine isprominently converted to the active metabolite mesoridazine(discussed next), which probably contributes to the antipsychoticactivity of thioridazine.
Biological Activity
Dopamine receptor antagonist that displays antipsychotic activity.
Thioridazine hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 207)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| SNECOFRi Pvt Ltd | +91-9032850129 +91-9032850129 | Telangana, India | 403 | 58 | Inquiry |
| Dishman Carbogen Amcis Ltd (Dishman Group) | +91-2717420100 +91-8154017093 | Gujarat, India | 90 | 58 | Inquiry |
| aistrifarma | +91-6374274350 +91-7708086868 | Tamil Nadu, India | 15 | 58 | Inquiry |
| Meck Pharmaceuticals and Chemicals Pvt. Ltd. | +91-9898053709 +91-9898540709 | Gujarat, India | 44 | 58 | Inquiry |
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6257 | 58 | Inquiry |
| A.J Chemicals | 91-9810153283 | New Delhi, India | 6100 | 58 | Inquiry |
| TCI Chemicals (India) Pvt. Ltd. | 1800 425 7889 | New Delhi, India | 6768 | 58 | Inquiry |
| Pharmaffiliates Analytics and Synthetics P. Ltd | +91-172-5066494 | Haryana, India | 6739 | 58 | Inquiry |
| Maxus Chemical Company | 08069033763Ext 243 | Ahmedabad, India | 2 | 58 | Inquiry |
| OCEAN TRADING CORPORATION | +91(22) 24921669 | New Delhi, India | 6202 | 58 | Inquiry |
130-61-0(Thioridazine hydrochloride)Related Search:
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ThioridazinHCl
Thioridazinhydrochlorid
Thioridazine chloridate
USAF SZ-B
melleril(tablet)
usafsz-3
10-[2-(1-Methyl-2-piperidinyl)ethyl]-2-(methylthio)-10H-phenothiazine Hydrochloride
2-Methylmercapto-10-[2-(N-methyl-2-piperidyl)ethyl]phenothiazine Hydrochloride
Orsanil
Ridazin
Stalleril
10H-Phenothiazine, 10-2-(1-methyl-2-piperidinyl)ethyl-2-(methylthio)-, monohydrochloride
THIORIDAZINEHYDROCHLORIDE,USP
10-[3-(1-Methyl-2-piperidyl)ethyl]-2-(methylthio)phenothiazine hydrochloride
10H-Phenothiazine, 10-[2-(1-methyl-2-piperidinyl)ethyl]-2-(methylthio)-, monohydrochloride (9CI)
Novoridazine
NSC 186060
Phenothiazine, 10-[2-(1-methyl-2-piperidyl)ethyl]-2-(methylthio)-, hydrochloride (6CI, 7CI)
Phenothiazine, 10-[2-(1-methyl-2-piperidyl)ethyl]-2-(methylthio)-, monohydrochloride (8CI)
Thioridazine hydrochloride
10-(2-(1-methyl-2-piperidinyl)ethyl)-2-(methylthio)-10h-phenothiazinmono
10-(2-(1-methyl-2-piperidyl)ethyl)-2-(methylthio)-phenothiazinmonohydrochl
10-(2-(1-methyl-2-piperidyl)ethyl)-2-methylthiophenothiazinehydrochloride
2-methylmercapto-10-(2-(n-methyl-2-piperidyl)ethyl)phenothiazinehydrochlorid
mellarilhydrochloride
Thioridazine Hydrochloride (200 mg)
Dopamine Receptor Antagonist II, Thioridazine, HCl
THIORIDAZINE HCL
10-[2-(1-METHYL-2-PIPERIDYL)ETHYL]-2-(METHYLTHIO)-10H-PHENOTHIAZINE HYDROCHLORIDE
10-[2-(1-METHYL-2-PIPERIDYL)-ETHYL]-2-[METHYLTHIOL]-PHENOTHIAZINE HYDROCHLORIDE
LABOTEST-BB LT00451961
Dopamine Receptor Antagonist II, Thioridazine, HCl - CAS 130-61-0 - Calbiochem
Thioridazine hydrochloride 98%
HYDROGEN THIORIDAZINE CHLORIDE
10-[2-(1-methyl-2-piperidinyl)ethyl]-2-(methylthio)phenothiazine hydrochloride
Thioridazine hydrochloride CRS
10-[2-(1-methylpiperidin-2-yl)ethyl]-2-(methylsulfanyl)-10H-phenothiazine hydrochloride
hioridazinehydrochloride
10-[2-(1-Methylpiperidin-2-yl)ethyl]-2-(methylthio)-10H-phenothiazine Hydrochloride
Thioridazine hydrochloride USP/EP/BP
Thioridazine HydrochlorideQ: What is
Thioridazine Hydrochloride Q: What is the CAS Number of
Thioridazine Hydrochloride Q: What is the storage condition of
Thioridazine Hydrochloride Q: What are the applications of
Thioridazine Hydrochloride
TIANFU CEHM 130-61-0 Thioridazine hydrochloride
Thioridazine Hydrochloride (1663008)
465 (Maleate)
L-714
Thioridazine hydrochloride in methanol
130-61-0
C21H26N2S2HCl
C21H26N2S2ClH
C21H27ClN2S2
MELLARIL
Miscellaneous
Intermediates & Fine Chemicals
Pharmaceuticals
Dopamine receptor