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ChemicalBook > Product Catalogue >API >Nervous system drugs >Antipsychotics >Thioridazine hydrochloride

Thioridazine hydrochloride

Thioridazine hydrochloride Structure
  • ₹5560 - ₹36534.38
  • Product name: Thioridazine hydrochloride
  • CAS: 130-61-0
  • MF: C21H27ClN2S2
  • MW: 407.04
  • EINECS:204-992-8
  • MDL Number:MFCD00012655
  • Synonyms:ThioridazinHCl;Thioridazinhydrochlorid;Thioridazine chloridate;USAF SZ-B;melleril(tablet) ;usafsz-3 ;10-[2-(1-Methyl-2-piperidinyl)ethyl]-2-(methylthio)-10H-phenothiazine Hydrochloride;2-Methylmercapto-10-[2-(N-methyl-2-piperidyl)ethyl]phenothiazine Hydrochloride
6 prices
Selected condition:

Brand

  • TCI Chemicals (India)
  • Sigma-Aldrich(India)

Package

  • 500MG
  • 2G
  • 5G
  • 25G
  • ManufacturerTCI Chemicals (India)
  • Product numberT3102
  • Product descriptionThioridazine Hydrochloride
  • Packaging5G
  • Price₹6200
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberT3102
  • Product descriptionThioridazine Hydrochloride
  • Packaging25G
  • Price₹23700
  • Updated2022-05-26
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number324387
  • Product descriptionDopamine Receptor Antagonist II, Thioridazine, HCl - CAS 130-61-0 - Calbiochem The Dopamine Receptor Antagonist II, Thioridazine, HCl, also referenced under CAS 130-61-0, controls the biological activity of Dopamine Receptor. Thi
  • Packaging2G
  • Price₹5560
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberT9025
  • Product descriptionThioridazine hydrochloride ≥99%
  • Packaging5G
  • Price₹10879.13
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberPHR3143
  • Product descriptionThioridazine Hydrochloride pharmaceutical secondary standard, certified reference material
  • Packaging500MG
  • Price₹16724.63
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberT9025
  • Product descriptionThioridazine hydrochloride ≥99%
  • Packaging25G
  • Price₹36534.38
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) T3102 Thioridazine Hydrochloride 5G ₹6200 2022-05-26 Buy
TCI Chemicals (India) T3102 Thioridazine Hydrochloride 25G ₹23700 2022-05-26 Buy
Sigma-Aldrich(India) 324387 Dopamine Receptor Antagonist II, Thioridazine, HCl - CAS 130-61-0 - Calbiochem The Dopamine Receptor Antagonist II, Thioridazine, HCl, also referenced under CAS 130-61-0, controls the biological activity of Dopamine Receptor. Thi 2G ₹5560 2022-06-14 Buy
Sigma-Aldrich(India) T9025 Thioridazine hydrochloride ≥99% 5G ₹10879.13 2022-06-14 Buy
Sigma-Aldrich(India) PHR3143 Thioridazine Hydrochloride pharmaceutical secondary standard, certified reference material 500MG ₹16724.63 2022-06-14 Buy
Sigma-Aldrich(India) T9025 Thioridazine hydrochloride ≥99% 25G ₹36534.38 2022-06-14 Buy

Properties

Melting point :158-1600C
Boiling point :230°C (rough estimate)
Density :1.1227 (rough estimate)
refractive index :1.5610 (estimate)
storage temp. :2-8°C
solubility :H2O: soluble250 mg plus 5 ml of solvent, clear, colorless to faintly yellow
form :Off-white solid
color :White to Almost white
Water Solubility :Soluble in water (75 mM), DMSO (100 mM), chloroform, ethanol, and methanol.
Sensitive :Light Sensitive & Hygroscopic
λmax :317nm(EtOH)(lit.)
Merck :14,9359
InChIKey :NZFNXWQNBYZDAQ-UHFFFAOYSA-N
CAS DataBase Reference :130-61-0(CAS DataBase Reference)
NIST Chemistry Reference :Thioridazine hydrochloride(130-61-0)
EPA Substance Registry System :10H-Phenothiazine, 10-[2-(1-methyl-2-piperidinyl)ethyl]-2-(methylthio)-, monohydrochloride (130-61-0)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P501 Dispose of contents/container to..…

Description

Thioridazine is a conventional, or typical, antipsychotic drug that potently activates several neuroreceptors, including serotonin (Kis = 10, 60, and 57 nM for 5-HT2A, 5-HT2C, and 5-HT6, respectively), dopamine D2 (Ki = 11 nM), and adrenergic α1A (Ki = 5 nM) receptors. In addition to its use in neurological disorders, thioridazine has efficacy in drug resistant tuberculosis.

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