Promethazine hydrochloride
- ₹625.1 - ₹17991.15
- Product name: Promethazine hydrochloride
- CAS: 58-33-3
- MF: C17H21ClN2S
- MW: 320.88
- EINECS:200-375-2
- MDL Number:MFCD00012652
- Synonyms:10-(2-dimethylamino-1-propyl)phenothiazine hydrochloride;PROMETHAZINE HYDROCHLORIDE;10-(2-(dimethylamino)propyl)phenothiazinemonohydrochloride ;10-(2-(dimethylamino)propyl)-phenothiazinmonohydrochloride ;promethazinen-(2’-dimethylamino-2’-methylethyl)phenothiazinehydrochloride ;promethiazin ;pyrethia ;romegranhydrochloride
7 prices
Selected condition:
Brand
- TCI Chemicals (India)
- Sigma-Aldrich(India)
Package
- 100MG
- 1G
- 1ML
- 25G
- 100G
- ManufacturerTCI Chemicals (India)
- Product numberP2029
- Product descriptionPromethazine Hydrochloride
- Packaging25G
- Price₹4100
- Updated2022-05-26
- Buy
- ManufacturerTCI Chemicals (India)
- Product numberP2029
- Product descriptionPromethazine Hydrochloride
- Packaging100G
- Price₹8800
- Updated2022-05-26
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberP-111
- Product descriptionPromethazine hydrochloride solution 1.0?mg/mL (1% 1 M HCl in Methanol (as free base)), ampule of 1?mL, certified reference material, Cerilliant?
- Packaging1ML
- Price₹625.1
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberP4651
- Product descriptionPromethazine hydrochloride
- Packaging25G
- Price₹6733.15
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberPHR1467
- Product descriptionPromethazine Hydrochloride Pharmaceutical Secondary Standard; Certified Reference Material
- Packaging1G
- Price₹8313.6
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product number46682
- Product descriptionPromethazine hydrochloride VETRANAL?, analytical standard
- Packaging100MG
- Price₹10651.8
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberP4651
- Product descriptionPromethazine hydrochloride
- Packaging100G
- Price₹17991.15
- Updated2022-06-14
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
TCI Chemicals (India) | P2029 | Promethazine Hydrochloride | 25G | ₹4100 | 2022-05-26 | Buy |
TCI Chemicals (India) | P2029 | Promethazine Hydrochloride | 100G | ₹8800 | 2022-05-26 | Buy |
Sigma-Aldrich(India) | P-111 | Promethazine hydrochloride solution 1.0?mg/mL (1% 1 M HCl in Methanol (as free base)), ampule of 1?mL, certified reference material, Cerilliant? | 1ML | ₹625.1 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | P4651 | Promethazine hydrochloride | 25G | ₹6733.15 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | PHR1467 | Promethazine Hydrochloride Pharmaceutical Secondary Standard; Certified Reference Material | 1G | ₹8313.6 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | 46682 | Promethazine hydrochloride VETRANAL?, analytical standard | 100MG | ₹10651.8 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | P4651 | Promethazine hydrochloride | 100G | ₹17991.15 | 2022-06-14 | Buy |
Properties
Melting point :230-232°C
Flash point :9℃
storage temp. :2-8°C
solubility :Very soluble in water, freely soluble in ethanol (96 per cent) and in methylene chloride.
form :Solid
color :White to Almost white
PH :pH (50g/L, 25℃) : 4.0~6.0
λmax :297nm(H2O)(lit.)
Merck :14,7786
BRN :4166397
BCS Class :1,3
InChI :InChI=1S/C17H20N2S.ClH/c1-13(18(2)3)12-19-14-8-4-6-10-16(14)20-17-11-7-5-9-15(17)19;/h4-11,13H,12H2,1-3H3;1H
InChIKey :XXPDBLUZJRXNNZ-UHFFFAOYSA-N
SMILES :N1(CC(C)N(C)C)C2C=CC=CC=2SC2=CC=CC=C12.Cl
CAS DataBase Reference :58-33-3(CAS DataBase Reference)
EPA Substance Registry System :Promethazine hydrochloride (58-33-3)
Flash point :9℃
storage temp. :2-8°C
solubility :Very soluble in water, freely soluble in ethanol (96 per cent) and in methylene chloride.
form :Solid
color :White to Almost white
PH :pH (50g/L, 25℃) : 4.0~6.0
λmax :297nm(H2O)(lit.)
Merck :14,7786
BRN :4166397
BCS Class :1,3
InChI :InChI=1S/C17H20N2S.ClH/c1-13(18(2)3)12-19-14-8-4-6-10-16(14)20-17-11-7-5-9-15(17)19;/h4-11,13H,12H2,1-3H3;1H
InChIKey :XXPDBLUZJRXNNZ-UHFFFAOYSA-N
SMILES :N1(CC(C)N(C)C)C2C=CC=CC=2SC2=CC=CC=C12.Cl
CAS DataBase Reference :58-33-3(CAS DataBase Reference)
EPA Substance Registry System :Promethazine hydrochloride (58-33-3)
Safety Information
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Description
Promethazine is a first generation histamine H1 receptor antagonist (Ki = 2.6 nM) whose antihistamine activity has been reported in guinea pigs and mice at ED50 values of 0.43 and 5.9 mg/kg, respectively. Promethazine can penetrate the CNS, depressing central H1 receptor activity, which may relate to its sedative properties, and can also inhibit muscarinic acetylcholine receptors (Ki = 22 nM). Furthermore, 32 mg/kg promethazine demonstrates antiemetic effects in ferret models of motion sickness or chemotherapy-induced nausea.More related product prices
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