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ChemicalBook > Product Catalogue >API >Antiallergic drugs >Antihistamines >Cetirizine dihydrochloride

Cetirizine dihydrochloride

Cetirizine dihydrochloride Structure
  • ₹3648.03 - ₹26304.75
  • Product name: Cetirizine dihydrochloride
  • CAS: 83881-52-1
  • MF: C21H26Cl2N2O3
  • MW: 425.35
  • EINECS:620-533-8
  • MDL Number:MFCD00941428
  • Synonyms:(2-(4-((4-chlorophenyl)phenylmethyl)-1-piperazinyl)ethoxy)aceticaciddihydro ;2-[2-[4-[(4-chlorophenyl)-phenyl-methyl]piperazin-1-yl]ethoxy]acetic acid dihydrochloride;Cetirizine Hydrochloride (250 mg);Alercet;Alerid;Cesta;Cetiriz;Cetrak
Price7 Properties Safety Information Description
7 prices
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Brand

  • Sigma-Aldrich(India)
  • TCI Chemicals (India)

Package

  • 50MG
  • 250MG
  • 1G
  • 5G
  • 25G
  • ManufacturerSigma-Aldrich(India)
  • Product numberC3618
  • Product descriptionCetirizine dihydrochloride ≥98% (HPLC)
  • Packaging250MG
  • Price₹26304.75
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberPHR1656
  • Product descriptionCetirizine Hydrochloride Pharmaceutical Secondary Standard; Certified Reference Material
  • Packaging1G
  • Price₹9818.28
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberC3618
  • Product descriptionCetirizine dihydrochloride ≥98% (HPLC)
  • Packaging50MG
  • Price₹5856.33
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number89126
  • Product descriptionCetirizin dihydrochloride ≥98.0% (HPLC)
  • Packaging1G
  • Price₹3994.43
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number89126
  • Product descriptionCetirizin dihydrochloride ≥98.0% (HPLC)
  • Packaging50MG
  • Price₹3648.03
  • Updated2022-06-14
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberC2316
  • Product descriptionCetirizine Dihydrochloride
  • Packaging25G
  • Price₹8800
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberC2316
  • Product descriptionCetirizine Dihydrochloride
  • Packaging5G
  • Price₹8300
  • Updated2022-05-26
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) C3618 Cetirizine dihydrochloride ≥98% (HPLC) 250MG ₹26304.75 2022-06-14 Buy
Sigma-Aldrich(India) PHR1656 Cetirizine Hydrochloride Pharmaceutical Secondary Standard; Certified Reference Material 1G ₹9818.28 2022-06-14 Buy
Sigma-Aldrich(India) C3618 Cetirizine dihydrochloride ≥98% (HPLC) 50MG ₹5856.33 2022-06-14 Buy
Sigma-Aldrich(India) 89126 Cetirizin dihydrochloride ≥98.0% (HPLC) 1G ₹3994.43 2022-06-14 Buy
Sigma-Aldrich(India) 89126 Cetirizin dihydrochloride ≥98.0% (HPLC) 50MG ₹3648.03 2022-06-14 Buy
TCI Chemicals (India) C2316 Cetirizine Dihydrochloride 25G ₹8800 2022-05-26 Buy
TCI Chemicals (India) C2316 Cetirizine Dihydrochloride 5G ₹8300 2022-05-26 Buy

Properties

Melting point :110-115°C
storage temp. :2-8°C
solubility :H2O: soluble5mg/mL, clear
form :powder
color :white to beige
Water Solubility :Soluble in water, DMSO, ethanol, and methanol.
Merck :14,2022
BCS Class :1,3
Stability :Hygroscopic
InChIKey :PGLIUCLTXOYQMV-UHFFFAOYSA-N
CAS DataBase Reference :83881-52-1(CAS DataBase Reference)
EPA Substance Registry System :Acetic acid, 2-[2-[4-[(4-chlorophenyl)phenylmethyl]-1-piperazinyl]ethoxy]-, hydrochloride (1:2) (83881-52-1)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P501 Dispose of contents/container to..…

Description

Cetirizine is a bioactive carboxylated metabolite of hydroxyzine that acts as a selective histamine H1 receptor antagonist (pKi = 8). As a second generation antihistamine, it is non-sedating due to low lipophilicity, which prevents blood-brain barrier transit. Cetirizine is a racemic mixture composed of equal amounts of two enantiomers, R-levocetirizine and S-dextrocetirizine, with pharmacological activity residing primarily in the (R)-isomer. Cetirizine has also been shown to inhibit eosinophil chemotaxis and leukotriene B4 release independent from H1 antagonism.

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