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L-Menthyl acetate

L-Menthyl acetate Structure
CAS No.
2623-23-6
Chemical Name:
L-Menthyl acetate
Synonyms
FEMA 2668;Brn 2208505;Acetoxymenthane;L-Menthylacetat;Menthyl Acatate;1-MENTHYLACETATE;L-MENTHYL ACETATE;(+)-Isocorynoline;MENTHYL ACETATE, L-;(-)-Menthyl Acetate
CBNumber:
CB7117565
Molecular Formula:
C12H22O2
Molecular Weight:
198.3
MOL File:
2623-23-6.mol
MSDS File:
SDS
Modify Date:
2024/7/2 8:55:14

L-Menthyl acetate Properties

Melting point <25 °C
Boiling point 229-230 °C(lit.)
alpha -81°(20/D, c=8, C6H6)
Density 0.92 g/mL at 25 °C(lit.)
vapor pressure 45Pa at 20℃
refractive index n20/D 1.447(lit.)
FEMA 2668 | MENTHYL ACETATE (ISOMER UNSPECIFIED)
Flash point 171 °F
storage temp. Sealed in dry,Room Temperature
solubility Chloroform (Slightly), Methanol (Slightly)
form Liquid
color Colourless
Specific Gravity 0.922
Odor at 100.00 %. mentholic minty herbal tea fruity woody floral earthy
Odor Type mentholic
optical activity [α]20/D 81°, c = 8 in benzene
Water Solubility 23.2mg/L at 20℃
JECFA Number 431
Merck 14,5839
BRN 2208505
LogP 4.39 at 25℃
CAS DataBase Reference 2623-23-6(CAS DataBase Reference)
EPA Substance Registry System Cyclohexanol, 5-methyl-2-(1-methylethyl)-, acetate, (1R,2S,5R)- (2623-23-6)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H227
Precautionary statements  P210e-P280a-P370+P378a-P403+P235-P501a
Safety Statements  24/25
RIDADR  NA 1993 / PGIII
WGK Germany  3
RTECS  AI5900000
TSCA  Yes
HS Code  2915 39 00
Toxicity LD50 orally in Rabbit: > 5000 mg/kg LD50 dermal Rabbit > 5000 mg/kg
NFPA 704
2
0 0

L-Menthyl acetate price More Price(11)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) W266825 L-Menthyl acetate natural, ≥98%, FCC, FG 2623-23-6 1SAMPLE-K ₹5196 2022-06-14 Buy
Sigma-Aldrich(India) W266825 L-Menthyl acetate natural, ≥98%, FCC, FG 2623-23-6 1KG ₹39273.1 2022-06-14 Buy
Sigma-Aldrich(India) 8.16147 (R)-(-)-Menthyl acetate for synthesis 2623-23-6 10ML ₹6809.99 2022-06-14 Buy
Sigma-Aldrich(India) 8.16147 (R)-(-)-Menthyl acetate for synthesis 2623-23-6 100ML ₹20820 2022-06-14 Buy
Sigma-Aldrich(India) 45985 (1R)-(−)-Menthyl acetate analytical standard 2623-23-6 1ML ₹11810.08 2022-06-14 Buy
Product number Packaging Price Buy
W266825 1SAMPLE-K ₹5196 Buy
W266825 1KG ₹39273.1 Buy
8.16147 10ML ₹6809.99 Buy
8.16147 100ML ₹20820 Buy
45985 1ML ₹11810.08 Buy

L-Menthyl acetate Chemical Properties,Uses,Production

Chemical Properties

(1R)-(-)-Menthyl acetate occurs in peppermint oils. It is a colorless liquid with a fresh, fruity, peppermint odor.
(?)-Menthyl acetate is prepared by acetylation of (?)-menthol (e.g., with acetic anhydride). It is used mainly in peppermint flavors and reconstituted peppermint oils, but also to a small extent in perfumery.

Uses

L-Menthyl Acetate, and its derivatives, is used as a penetration enhancers, to enhance the skin permeation of various drugs with differing lipophilicities, such as 5-aminolevulinic acid (ALA), 5-fluorouracil (5-FU), isosorbide dinitrate (ISDN), lidocaine (LD), etc.

Safety Profile

Low toxicity by ingestion and skin contact. A skin irritant. When heated to decomposition it emits acrid smoke and irritating fumes.

Synthesis

L-Menthyl acetate is produced by direct esterification of racemicMenthol with Acetic acid under azeotropic conditions.

L-Menthyl acetate Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 258)Suppliers
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Samde Aromatic Pvt Ltd +91-9351546864 +91-9351546864 Rajasthan, India 21 58 Inquiry
Bhagat Aromatics Ltd +91-1204044300 +91-9321155125 Uttar Pradesh, India 24 58 Inquiry
B D Aromatics Pvt., Ltd. 91-9837047555 Uttar Pradesh, India 9 58 Inquiry
Shanti Aromatics 08048952928 Uttar Pradesh, India 26 58 Inquiry
Hello Aromachem Private Limited 91-9811468688 Uttar Pradesh, India 6 58 Inquiry
Musks & Fragrance +91-22-2624 9902 / 2624 4121 /2 670 3348 New Delhi, India 124 58 Inquiry
CHEMSWORTH +91-261-2397244 New Delhi, India 6707 30 Inquiry
TCI Chemicals (India) Pvt. Ltd. 1800 425 7889 New Delhi, India 6778 58 Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
Kelvin Natural Mint Private Limited 08048250221Ext 669 Uttar Pradesh, India 2 58 Inquiry
2-isopropyl-5-methyl-,acetate,l-cyclohexan-1-o 5-methyl-2-(1-methylethyl)-,acetate,[1R-(1.alpha.,2.beta.,5.alpha.)]-Cyclohexanol acetate,(1r,3r,4s)-(-)-mentho MENTHYL ACETATE, L- L-MENTHYL ACETATE FEMA 2668 (-)-ACETOXY-P-MENTHANE (-)-(1R)-MENTHYL ACETATE (1R)-(-)-MENTHYL ACETATE Acetoxymenthane L-MENTHYL ACETATE 98+% NATURAL FCC (-)-(1R)-MENTHYL ACETATE, TERPENE STANDA RD L-(-)-ACETOXY-P-MENTHANE Cyclohexanol, 5-methyl-2-(1-methylethyl)-, acetate, (1R,2S,5R)- 1-MENTHYLACETATE L-Menthylacetat MENTHYLACETAT NATUERLICH (5-Methyl-2-propan-2-ylcyclohexyl) acetate (-)-ACETOXY-P-MENTHANE 98+% (-)-MENTHYL ACETATE WITH GC MENTHYL ACETATE, NATURAL (IR)-(-)-MENTHYL ACETATE (-)-Acetic acid (1R)-5β-methyl-2α-isopropylcyclohexan-1β-yl ester aceticacid(1R)-menthylester cyclohexanol,5-methyl-2-(1-methylethyl)-,acetate,(1r-(1alpha,2beta,5alpha) cyclohexanol,5-methyl-2-(1-methylethyl)-,acetate,[1theta-(1alpha,2beta,5 l-p-menth-3-ylacetate p-menth-3-ylester,l-aceticaci (R)-(-)-MENTHYL ACETATE Acetic acid, p-menth-3-yl ester, L- Brn 2208505 Cyclohexan-1-ol, 2-isopropyl-5-methyl-, acetate, L- Cyclohexanol, 5-methyl-2-(1-methylethyl)-, 1-acetate, (1R,2S,5R)- Cyclohexanol, 5-methyl-2-(1-methylethyl)-, acetate, (1R-(1alpha,2beta,5alpha))- (9ci) Cyclohexanol, 5-methyl-2-(1-methylethyl)-, acetate, (1theta-(1alpha,2beta,5alpha))- MENTHYL ACETATE, (-)-(SG) (-)-Acetic acid (1R,3R,4S)-p-menthan-3-yl ester L-Menthyl acetate,(1R)-()-Menthyl acetate (R)-(-)-MENTHYL ACETATE FOR SYNTHESIS (1R,2S,5R)-2-isopropyl-5-Methylcyclohexyl acetate (1R)-(-)-Menthyl acetate 98% (5R)-2-Isopropyl-5-methylcyclohexyl acetate laevo-menthyl acetate [(1R,2S,5R)-5-methyl-2-propan-2-ylcyclohexyl] acetate (-)-Menthyl Acetate > (-)-Menthyl Acetate (1R)-(-)-Menthyl acetate USP/EP/BP Menthyl Acatate [(5R)-5-methyl-2-propan-2-ylcyclohexyl] acetate (+)-Isocorynoline (-)-Menthyl Acetate, ≥ 98.0% 2623-23-6 Analytical Standards Analytical Chromatography Product Catalog Alphabetic Asymmetric Synthesis Chiral Building Blocks Terpenes