Sodium propylparaben
- CAS No.
- 35285-69-9
- Chemical Name:
- Sodium propylparaben
- Synonyms
- PROPYLPARABEN SODIUM;SODIUM PROPYL HYDROXYBENZOATE;SODIUM PROPYL-P-HYDROXYBENZOATE;SodiuM 4-(propoxycarbonyl)phenolate;PROPYL 4-HYDROXYBENZOATE SODIUM SALT;D02459;Paradept;propylparabens;NIPASOL SODIUM;SOIDUM PROPYLPARABEN
- CBNumber:
- CB7176672
- Molecular Formula:
- C10H13NaO3
- Molecular Weight:
- 204.2
- MOL File:
- 35285-69-9.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/7/26 17:49:17
| Melting point | 302°C |
|---|---|
| Density | 1.24 g/cm3 (25 °C) |
| vapor pressure | 0.001Pa at 20℃ |
| storage temp. | Store at +15°C to +25°C. |
| solubility | Freely soluble in water, sparingly soluble in ethanol (96 per cent), practically insoluble in methylene chloride. |
| pka | 8.46[at 20 ℃] |
| form | Solid |
| color | White to Off-White |
| PH | 9.5-10.5 (1g/l, H2O, 20°C) |
| Water Solubility | 1000g/L at 23℃ |
| Stability | Hygroscopic |
| LogP | 0.27 at 23℃ |
| CAS DataBase Reference | 35285-69-9(CAS DataBase Reference) |
| EPA Substance Registry System | Propylparaben sodium (35285-69-9) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS05 |
|---|---|
| Signal word | Danger |
| Hazard statements | H318 |
| Precautionary statements | P280-P305+P351+P338 |
| Safety Statements | 22-24/25 |
| WGK Germany | 2 |
| RTECS | DH2850000 |
| HS Code | 2918 29 00 |
| Toxicity | LD50 orally in Rabbit: > 5000 mg/kg |
Sodium propylparaben price More Price(4)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| ottokemi | P 2676 | Propyl 4-hydroxybenzoate sodium salt 99% | 35285-69-9 | 500gm | ₹2088 | 2022-05-26 | Buy |
| SRL | 52950 | Propyl-4-Hydroxybenzoate Sodium Salt (Propyl Paraben Sodium) ExiPlus, Multi-Compendial, 94-102% | 35285-69-9 | 500Gms | ₹1820 | 2022-05-26 | Buy |
| ottokemi | P 2676 | Propyl 4-hydroxybenzoate sodium salt 99% | 35285-69-9 | 5kg | ₹18909 | 2022-05-26 | Buy |
| SRL | 52950 | Propyl-4-Hydroxybenzoate Sodium Salt (Propyl Paraben Sodium) ExiPlus, Multi-Compendial, 94-102% | 35285-69-9 | 5kg | ₹15160 | 2022-05-26 | Buy |
Sodium propylparaben Chemical Properties,Uses,Production
Chemical Properties
White or almost white, hygroscopic, crystalline powder.
Uses
Sodium Propylparaben is a preservative. Sodium Propylparaben is also an excipient used in various pharmaceutical formulations.
Production Methods
Propylparaben sodium is produced from benzoic acid.
Pharmaceutical Applications
Propylparaben sodium is used as an antimicrobial or antifungal preservative in oral pharmaceuticals and in many water-based cosmetics. It is generally used in combination with other paraben esters.
Contact allergens
This substance is one of the parabens family. Parabens are esters formed by p-hydroxybenzoic acid and an alcohol. They are largely used as biocides in cosmetics and toiletries, medicaments, or food. They have synergistic power with other biocides. Parabens can induce allergic contact dermatitis, mainly in chronic dermatitis and wounded skin.
Safety
Propylparaben sodium is used in oral pharmaceuticals and
cosmetics. The pure form is toxic by the IV route and moderately
toxic by ingestion and the IP route. Propylparaben sodium may
cause asthma, rashes, and hyperactivity.
LD50 (mouse, IP): 0.49 g/kg
LD50 (mouse, IV): 0.18 g/kg
LD50 (mouse, oral): 3.7 g/kg
storage
Propylparaben sodium is stable under normal conditions. It decomposes on heating. Store in a tightly closed container.
Incompatibilities
The activity of propylparaben sodium can be adversely affected by the presence of other excipients or active ingredients, such as atropine, essential oils, iron, magnesium trisilicate, talc, polysorbate 80 and other nonionic surfactants, sorbitol, weak alkalis, and strong acids.
Regulatory Status
Included in the FDA Inactive Ingredients Database (oral capsules, tablets, suspensions). Accepted for use as a food additive in Europe. Included in nonparenteral medicines (oral capsules, mixtures, orodispersible tablets, solutions and suspensions; cutaneous emulsions) licensed in the UK.
Sodium propylparaben Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| Cardkem Pharma Pvt Ltd | +91 8866051980 | Ahmedabad, India | 32 | 58 | Inquiry |
| Frolic Pharmachem | +919711094561 | Himachal Pradesh, India | 94 | 58 | Inquiry |
| Shreenath Chemicals | +91-8369634120 +91-8369634120 | Maharashtra, India | 48 | 58 | Inquiry |
| Murli Krishna Exports Pvt Ltd | +91-2225631595 +91-2225631594 | New Delhi, India | 185 | 58 | Inquiry |
| Kenoor Organics Private Limited | +91-7227026011 +91-7227026012 | Gujarat, India | 29 | 58 | Inquiry |
| Salicylates and Chemicals Pvt. Ltd. | +91-8879630551 +91-8898005838 | Maharashtra, India | 61 | 58 | Inquiry |
| Mruchem | +91-8087147166 +91-8087147166 | Gujarat, India | 52 | 58 | Inquiry |
| Covalent Incorporation | +91-9033666099 +91-9033666099 | Gujarat, India | 50 | 58 | Inquiry |
| JD Chem India | +91-9899117932 +91-9555260045 | New Delhi, India | 41 | 58 | Inquiry |
| Rasula Pharmaceuticals And Fine Chemicals | +91-4023774210 +91-4023771063 | Telangana, India | 7 | 58 | Inquiry |
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