STEAROYL ETHANOLAMIDE
- CAS No.
- 111-57-9
- Chemical Name:
- STEAROYL ETHANOLAMIDE
- Synonyms
- SEA;N-(2-hydroxyethyl)stearamide;CERAMID;STEARAMIDE MEA;AM-1105;STEAROYL ETHANOLAMIDE;N-Stearoylethanolamide;Stearyl monoethanolamide;stearic monoethanolamide;STEARIC ACID ETHANOLAMIDE
- CBNumber:
- CB7184343
- Molecular Formula:
- C20H41NO2
- Molecular Weight:
- 327.55
- MOL File:
- 111-57-9.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/7/2 8:55:16
| Melting point | 103-104 °C(Solv: ethanol (64-17-5)) |
|---|---|
| Boiling point | 486.0±28.0 °C(Predicted) |
| Density | 0.904±0.06 g/cm3(Predicted) |
| vapor pressure | 0Pa at 20℃ |
| storage temp. | −20°C |
| solubility | DMF: >2 mg/ml; DMSO: >100 μg/ml; Ethanol: >2 mg/ml; PBS pH 7.2: >100 μg/ml |
| form | crystalline |
| pka | 14.49±0.10(Predicted) |
| color | White to light yellow |
| Water Solubility | 1mg/L at 20℃ |
| InChI | InChI=1S/C20H41NO2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-20(23)21-18-19-22/h22H,2-19H2,1H3,(H,21,23) |
| InChIKey | OTGQIQQTPXJQRG-UHFFFAOYSA-N |
| SMILES | C(NCCO)(=O)CCCCCCCCCCCCCCCCC |
| LogP | 4.46 at 20℃ |
| EPA Substance Registry System | N-(2-Hydroxyethyl)octadecanamide (111-57-9) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS05 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H315-H318-H402-H412 | |||||||||
| Precautionary statements | P264-P273-P280-P302+P352-P305+P351+P338-P310-P321-P362+P364-P332+P313-P501 | |||||||||
| Safety Statements | 22-24/25 | |||||||||
| WGK Germany | 2 | |||||||||
| NFPA 704 |
|
STEAROYL ETHANOLAMIDE Chemical Properties,Uses,Production
Uses
Stearoyl Ethanolamide is a prolific fatty acid ethanolamide produced by PLD hydrolysis of membrane phospholipids. Stearoyl Ethanolamide is also used for studying the effect on endocannabinoid signalling and BBB integrity in systemic inflammation.
Definition
ChEBI: An N-(long-chain-acyl)ethanolamine that is the ethanolamide of octadecanoic acid.
Preparation
In the stirred state, fatty acids (1.0 mmol, 1.0 equiv) were added to CH2Cl2 (5 mL), followed by CDI (0.178 g, 1.1 mmol, 1.1 equiv). After 30 min, the amine (1.1 mmol, 1.1equiv.)was added. Added CH2Cl2 (25ml) and saturated NH4Cl aqueous solution after 12 h. HCl was added to the mixture to adjusted pH=2. After the organic phase was separated, the aqueous layer was further extracted with CH2Cl2 (3 × 10 mL). The organic phase was collected and placed on Na2SO4 to dried, and filtered. Finally, the product (STEAROYL ETHANOLAMIDE) was obtained by vacuum concentration.
STEAROYL ETHANOLAMIDE Preparation Products And Raw materials
Raw materials
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chevron_rightPreparation Products
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| SynZeal Research Pvt Ltd | +1 226-802-2078 | Gujarat, India | 6522 | 58 | Inquiry |
| Career Henan Chemica Co | +86-0371-86658258 +8613203830695 | China | 30253 | 58 | Inquiry |
| GIHI CHEMICALS CO.,LIMITED | +8618058761490 | China | 49999 | 58 | Inquiry |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | China | 21669 | 55 | Inquiry |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | China | 49391 | 58 | Inquiry |
| Zhengzhou Alfa Chemical Co.,Ltd | +8618530059196 | China | 13127 | 58 | Inquiry |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | United States | 19892 | 58 | Inquiry |
| Dayang Chem (Hangzhou) Co.,Ltd. | 571-88938639 +8617705817739 | China | 52861 | 58 | Inquiry |
| Alfa Chemistry | United States | 24072 | 58 | Inquiry | |
| Shaanxi LonierHerb Bio Technology Co Ltd | +86-86-+86-86-029-87551862 +8617702909819 | China | 2605 | 58 | Inquiry |