Amisulpride
- CAS No.
- 71675-85-9
- Chemical Name:
- Amisulpride
- Synonyms
- 4-amino-n-((1-ethyl-2-pyrrolidinyl)methyl)-5-(ethylsulfonyl)-2-methoxybenzam;4-amino-N-((1-ethylpyrrolidin-2-yl)methyl)-5-(ethylsulfonyl)-2-methoxybenzamide;SOCIAN;SOLIAN;AmisuL;Sulamid;DENIBAN;DAN-2163;Amisulprid;AMISULPRIDE
- CBNumber:
- CB7312326
- Molecular Formula:
- C17H27N3O4S
- Molecular Weight:
- 369.48
- MOL File:
- 71675-85-9.mol
- Modify Date:
- 2024/7/26 15:15:06
| Melting point | 124-128 |
|---|---|
| Boiling point | 558.9±50.0 °C(Predicted) |
| Density | 1.200±0.06 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| solubility | DMSO: ≥5 mg/mL |
| form | solid |
| pka | 13.73±0.46(Predicted) |
| color | white |
| Merck | 14,485 |
| InChI | InChI=1S/C17H27N3O4S/c1-4-20-8-6-7-12(20)11-19-17(21)13-9-16(25(22,23)5-2)14(18)10-15(13)24-3/h9-10,12H,4-8,11,18H2,1-3H3,(H,19,21) |
| InChIKey | NTJOBXMMWNYJFB-UHFFFAOYSA-N |
| SMILES | C(NCC1CCCN1CC)(=O)C1=CC(S(CC)(=O)=O)=C(N)C=C1OC |
| CAS DataBase Reference | 71675-85-9(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302 | |||||||||
| Precautionary statements | P301+P312+P330 | |||||||||
| Hazard Codes | Xn | |||||||||
| Risk Statements | 22 | |||||||||
| Safety Statements | 22-24/25 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | CV2308701 | |||||||||
| HS Code | 2933.99.8290 | |||||||||
| Toxicity | LD50 in male mice (mg/kg): 56-60 i.v.; 175-180 i.p.; 224-250 s.c.; 1024-1054 orally (Thominet) | |||||||||
| NFPA 704 |
|
Amisulpride price More Price(4)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | A2729 | Amisulpride ≥98% (HPLC) | 71675-85-9 | 10MG | ₹13412.18 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | A2729 | Amisulpride ≥98% (HPLC) | 71675-85-9 | 50MG | ₹60230.3 | 2022-06-14 | Buy |
| TCI Chemicals (India) | A2450 | Amisulpride | 71675-85-9 | 100MG | ₹7600 | 2022-05-26 | Buy |
| TCI Chemicals (India) | A2450 | Amisulpride | 71675-85-9 | 1G | ₹14500 | 2022-05-26 | Buy |
Amisulpride Chemical Properties,Uses,Production
Description
Amisulpride i s a n antipsychotic agent structurally related to sulpiride and sultopride. Useful in the treatment of schizophrenia, it is not, however, without EPS liability.
Chemical Properties
Off-White Solid
Uses
Amisulpride is a neuroleptic agent, an analogue of Sulpiride (S689145). Amisulpride is used as an antipsychotic. Amisulpride is a dopamine receptor antagonist.
Biological Activity
Potent, selective dopamine D 2 and D 3 receptor antagonist. K i values are 2.8 and 3.2 nM respectively for human D 2 and D 3 and > 1000 nM for human D 1 , D 4 and D 5 receptors. Shows selectivity for presynaptic dopamine autoreceptors at low doses and blocks postsynaptic D 2 /D 3 receptors at higher doses. Preferentially interacts with limbic D 2 -like receptors in vivo . Atypical antipsychotic/antischizophrenic agent with limited extrapyrimidal side effects and a profile distinct from that of haloperidol and remoxipride.
Amisulpride Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 546)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| BIOCHEMICAL & SYNTHETIC PRODUCTS PVT. LT., | +91-91-8421973722 +91-9869455944 | Telangana, India | 31 | 58 | Inquiry |
| Anphar Laboratories Pvt Ltd | +91-9018670066 +91-9018670066 | Himachal Pradesh, India | 17 | 58 | Inquiry |
| Chynops Pharma | +919998000404 | Gujarat, India | 39 | 58 | Inquiry |
| Prayosha Health Care Pvt Ltd | +91-9924448881 +91-9924448881 | Gujarat, India | 15 | 58 | Inquiry |
| Aurobindo Pharma Limited | +914066725000 | Telangana, India | 112 | 58 | Inquiry |
| Viyash Life Sciences Pvt Ltd | +91-4023635052 +91-4023635052 | Telangana, India | 213 | 58 | Inquiry |
| Sun Pharmaceutical Industries Ltd | +91-2242244224 +91-2243244324 | Maharashtra, India | 108 | 58 | Inquiry |
| CTX Lifesciences Pvt Ltd | +91-2612399669 +91-7434851395 | Gujarat, India | 28 | 58 | Inquiry |
| Virupaksha Organics Pvt Ltd | +91-9440049755 +91-9848648601 | Telangana, India | 40 | 58 | Inquiry |
| Dayaram Pharma Chem | +91-9601766800 +91-9601766800 | Gujarat, India | 61 | 58 | Inquiry |
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4-amino-N-((1-ethylpyrrolidin-2-yl)methyl)-5-(ethylsulfonyl)-2-methoxybenzamide
4-amino-n-((1-ethyl-2-pyrrolidinyl)methyl)-5-(ethylsulfonyl)-2-methoxybenzam
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h . 2-c h loro-N,N-d i e th yle th a na mi ne (2-c h lorotri e th yla mi ne , (2-c h loroe th yl)d i e th yla mi ne ).
AMISULPRIDE IP/EP/BP
71675-85-9
C17H27N3O4S
DENIBAN
Dopamine receptor
Active Pharmaceutical Ingredients
Antipsychotic
Drug Analogues
Intermediates & Fine Chemicals
Pharmaceuticals