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DL-Serine

DL-Serine Structure
CAS No.
302-84-1
Chemical Name:
DL-Serine
Synonyms
SERINE;serin;DL-SER;DL-Serin;DL-Ser-OH;DL-SERINE;Serine, dl-;H-DL-SER-OH;DL-SERINE,FCC;DL-Serine >
CBNumber:
CB7345179
Molecular Formula:
C3H7NO3
Molecular Weight:
105.09
MOL File:
302-84-1.mol
MSDS File:
SDS
Modify Date:
2023/11/2 17:49:29

DL-Serine Properties

Melting point 240 °C (dec.) (lit.)
Boiling point 197.09°C (rough estimate)
Density 1.53
refractive index 1.4368 (estimate)
storage temp. Store below +30°C.
solubility H2O: soluble
form Crystalline Powder
pka 2.19(at 25℃)
color White
Odor Odorless
Water Solubility 50.23 g/L (25 ºC)
Merck 14,8460
BRN 1721402
LogP -3.460
CAS DataBase Reference 302-84-1(CAS DataBase Reference)
NIST Chemistry Reference DL-Serine(302-84-1)
EPA Substance Registry System Serine (302-84-1)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P302+P352-P305+P351+P338-P362+P364
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  24/25-36-26
WGK Germany  3
RTECS  VT8100000
TSCA  Yes
HS Code  29225000
NFPA 704
1
0 0

DL-Serine price More Price(14)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) S5386 DL-Serine BioReagent, suitable for cell culture, suitable for insect cell culture, ≥98% (HPLC) 302-84-1 25G ₹3572.25 2022-06-14 Buy
Sigma-Aldrich(India) S5386 DL-Serine BioReagent, suitable for cell culture, suitable for insect cell culture, ≥98% (HPLC) 302-84-1 100G ₹7988.85 2022-06-14 Buy
Sigma-Aldrich(India) S4375 DL-Serine ≥98% (TLC) 302-84-1 100G ₹6668.2 2022-06-14 Buy
Sigma-Aldrich(India) S4375 DL-Serine ≥98% (TLC) 302-84-1 1KG ₹37725.13 2022-06-14 Buy
Sigma-Aldrich(India) 8.41235 DL-Serine for synthesis 302-84-1 100G ₹5740 2022-06-14 Buy
Product number Packaging Price Buy
S5386 25G ₹3572.25 Buy
S5386 100G ₹7988.85 Buy
S4375 100G ₹6668.2 Buy
S4375 1KG ₹37725.13 Buy
8.41235 100G ₹5740 Buy

DL-Serine Chemical Properties,Uses,Production

Description

DL-Serine is a kind of neutral aliphatic amino acids containing hydroxyl groups with polarity but being uncharged, and belongs to nonessential amino acids for human body. It has a high content in sericin silk protein and fibroin protein. It can be formed from the methyl transfer reaction of glycine. It can also be converted to pyruvate or hydroxy pyruvate through deamination. It is also an important raw material for in vivo synthesis of choline and cysteine.

Chemical Properties

DL-Serine is a kind of colorless monoclinic columnar or lamellae crystal. It is soluble in water (at 20℃, the water solubility is 380g/L), insoluble in ether and ethanol; Decomposition point: 246℃.

Uses

DL-Serine is used in the synthesis of novel tryptoline derivatives as IDO (indoleamine 2,3-Deoxygenase) inhibitors, for potential use in Alzheimer’s treatment.

Definition

ChEBI: Serine is an alpha-amino acid that is alanine substituted at position 3 by a hydroxy group. It has a role as a fundamental metabolite. It is an alpha-amino acid and a polar amino acid. It contains a hydroxymethyl group. It is a conjugate base of a serinium. It is a conjugate acid of a serinate. It is a tautomer of a serine zwitterion.

Preparation

DL-serine is obtained by complexing glycine under the catalysis of copper ions and then combining with formaldehyde under alkaline conditions, followed by acidification, ion exchange, and crystallization in ethanol.?

Application

Serine is a non-essential amino acid and a natural ligand and allosteric activator of pyruvate kinase M2. Serine helps retain the skin's moisture balance.

Safety Profile

When heated to decomposition emits toxic fumes of NOx.

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DL-SERINE TECHNICAL GRADE DL-SERINE extrapure CHR DL-Serine Vetec(TM) reagent grade, 98% DL-SERINE UNLABELED DL-Ser-OH DL-Serine≥ 99% (Assay) rac-(R*)-2-Amino-3-hydroxypropionic acid rac-(R*)-3-Hydroxy-2-aminopropionic acid DL-Serine, extra pure DL-3-Hydroxy-α-alanine DL-β-Hydroxyalanine DL-Serine, Reagent DL-Serine, 99% 100GR DL-Serine, 99% 25GR DL-2-Amino-3-hydroxypropionic Acid H-DL-Ser-OH (R,S)-2-Amino-3-hydroxy-propionicacid L-HOCH2CH(NH2)COOH Serine, dl- (+/-)-2-AMINO-3-HYDROXYPROPIONIC ACID 2-AMINO-3-HYDROXY-PROPIONIC ACID DL-2-AMINO-3-HYDROXYPROPANOIC ACID DL-2-AMINO-3-HYDROXYPROPIONIC ACID DL-BETA-HYDROXYALANINE DL-SER DL-SERINE DL-SERINE CELL CULTURE TESTED DL-SERINE 99+% Dl-SerinePuriss99+% Dl-SerinePuriss DL-SERINE FOR BIOCHEMISTRY (n)-2-amino-3-hydroxypropionic acid DL-SERINE,FCC H-DL-SER-OH DL-Serin DL-SERINE PURE GRADE (2S)-2-ammonio-3-hydroxypropanoate DL-2-Aminohydracrylic acid Serine, 99%, for synthesis DL-Serine > DL-SERINE FOR SYNTHESIS 100 G threonine-protein kinase B-raf DL-Serine USP/EP/BP dextro,laevo-serine SERINE, (L)(302-84-1) SERINE serin 2-(methylamino)acetic acid (sarcosine) 302-84-1 302-83-1 202-84-1 Amino Acid Derivatives Peptide Synthesis Specialty Synthesis Serine [Ser, S] alpha-Amino Acids Amino Acids Biochemistry Amino Acids