DL-Serine
- CAS No.
- 302-84-1
- Chemical Name:
- DL-Serine
- Synonyms
- SERINE;serin;DL-SER;DL-Serin;DL-Ser-OH;DL-SERINE;Serine, dl-;H-DL-SER-OH;DL-SERINE,FCC;DL-Serine >
- CBNumber:
- CB7345179
- Molecular Formula:
- C3H7NO3
- Molecular Weight:
- 105.09
- MOL File:
- 302-84-1.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/11/13 11:39:26
| Melting point | 240 °C (dec.) (lit.) |
|---|---|
| Boiling point | 197.09°C (rough estimate) |
| Density | 1.53 |
| refractive index | 1.4368 (estimate) |
| storage temp. | Store below +30°C. |
| solubility | H2O: soluble |
| form | Crystalline Powder |
| pka | 2.19(at 25℃) |
| color | White |
| Odor | Odorless |
| Water Solubility | 50.23 g/L (25 ºC) |
| Merck | 14,8460 |
| BRN | 1721402 |
| LogP | -3.460 |
| CAS DataBase Reference | 302-84-1(CAS DataBase Reference) |
| NIST Chemistry Reference | DL-Serine(302-84-1) |
| EPA Substance Registry System | Serine (302-84-1) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P302+P352-P305+P351+P338-P362+P364 | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 24/25-36-26 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | VT8100000 | |||||||||
| TSCA | Yes | |||||||||
| HS Code | 29225000 | |||||||||
| NFPA 704 |
|
DL-Serine price More Price(14)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | S5386 | DL-Serine BioReagent, suitable for cell culture, suitable for insect cell culture, ≥98% (HPLC) | 302-84-1 | 25G | ₹3572.25 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | S5386 | DL-Serine BioReagent, suitable for cell culture, suitable for insect cell culture, ≥98% (HPLC) | 302-84-1 | 100G | ₹7988.85 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | S4375 | DL-Serine ≥98% (TLC) | 302-84-1 | 100G | ₹6668.2 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | S4375 | DL-Serine ≥98% (TLC) | 302-84-1 | 1KG | ₹37725.13 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 8.41235 | DL-Serine for synthesis | 302-84-1 | 100G | ₹5740 | 2022-06-14 | Buy |
DL-Serine Chemical Properties,Uses,Production
Description
DL-Serine is a kind of neutral aliphatic amino acids containing hydroxyl groups with polarity but being uncharged, and belongs to nonessential amino acids for human body. It has a high content in sericin silk protein and fibroin protein. It can be formed from the methyl transfer reaction of glycine. It can also be converted to pyruvate or hydroxy pyruvate through deamination. It is also an important raw material for in vivo synthesis of choline and cysteine.
Chemical Properties
DL-Serine is a kind of colorless monoclinic columnar or lamellae crystal. It is soluble in water (at 20℃, the water solubility is 380g/L), insoluble in ether and ethanol; Decomposition point: 246℃.
Uses
DL-Serine is used in the synthesis of novel tryptoline derivatives as IDO (indoleamine 2,3-Deoxygenase) inhibitors, for potential use in Alzheimer’s treatment.
Definition
ChEBI: Serine is an alpha-amino acid that is alanine substituted at position 3 by a hydroxy group. It has a role as a fundamental metabolite. It is an alpha-amino acid and a polar amino acid. It contains a hydroxymethyl group. It is a conjugate base of a serinium. It is a conjugate acid of a serinate. It is a tautomer of a serine zwitterion.
Preparation
DL-serine is obtained by complexing glycine under the catalysis of copper ions and then combining with formaldehyde under alkaline conditions, followed by acidification, ion exchange, and crystallization in ethanol.?
Application
Serine is a non-essential amino acid and a natural ligand and allosteric activator of pyruvate kinase M2. Serine helps retain the skin's moisture balance.
Safety Profile
When heated to decomposition emits toxic fumes of NOx.
DL-Serine Preparation Products And Raw materials
Raw materials
Preparation Products
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chevron_right| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| ANJI BIOSCIENCES | +91-9000100077 +91-9000100077 | Hyderabad, India | 429 | 58 | Inquiry |
| ARRAKIS INDUSTRIES LLP | +91 74995 32711 | Maharashtra, India | 1353 | 58 | Inquiry |
| Anand Agencies | 91-20-24454597 | Maharashtra, India | 2332 | 58 | Inquiry |
| Sisco Research Laboratories Pvt. Ltd. | +91-22-4268 5800 | Mumbai, India | 4315 | 58 | Inquiry |
| Maas Pharma Chemicals | +91-9958666224 | Delhi, India | 1607 | 58 | Inquiry |
| Loba Chemie Pvt., Ltd. | 91-22-66636663 | Maharashtra, India | 765 | 58 | Inquiry |
| LOBA CHEMIE PVT.LTD. | 91-22-6663 6699 | Mumbai, India | 3075 | 58 | Inquiry |
| Central Drug House(P) Ltd. | 91-11-49404040 | New Delhi, India | 6157 | 58 | Inquiry |
| CHEMSWORTH | +91-261-2397244 | New Delhi, India | 6700 | 30 | Inquiry |
| ALPHA CHEMIKA | +91-22-22061123 +91-22-66382501 | Mumbai, India | 1679 | 43 | Inquiry |
| Supplier | Advantage |
|---|---|
| ANJI BIOSCIENCES | 58 |
| ARRAKIS INDUSTRIES LLP | 58 |
| Anand Agencies | 58 |
| Sisco Research Laboratories Pvt. Ltd. | 58 |
| Maas Pharma Chemicals | 58 |
| Loba Chemie Pvt., Ltd. | 58 |
| LOBA CHEMIE PVT.LTD. | 58 |
| Central Drug House(P) Ltd. | 58 |
| CHEMSWORTH | 30 |
| ALPHA CHEMIKA | 43 |
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