MILBEMECTIN A4

MILBEMECTIN A4 Structure
CAS No.
51596-11-3
Chemical Name:
MILBEMECTIN A4
Synonyms
Milbemycin EP Impurity A;Milbemycin α3;milbemycin A4;milbemycinb-1;MILBEMECTIN A4;milbemectine a4;Antibiotic B-41A4;Milbemycin oxime A4;Milbemycin EP Imp A;B 41A4, MilbeMycin alpha3
CBNumber:
CB7359655
Molecular Formula:
C32H46O7
Molecular Weight:
542.7
MOL File:
51596-11-3.mol
Modify Date:
2024/7/2 8:55:16

MILBEMECTIN A4 Properties

Melting point 212-215°
alpha D20 +106° (c = 0.25 in acetone)
Boiling point 732.9±60.0 °C(Predicted)
Density 1.20±0.1 g/cm3(Predicted)
storage temp. 0-6°C
solubility DMF: soluble; DMSO: soluble; Ethanol: soluble; Methanol: soluble
form A solid
pka 12.46±0.70(Predicted)
color White to off-white
EPA Substance Registry System Milbemycin A4 (51596-11-3)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS08
Signal word  Danger
Hazard statements  H350
Precautionary statements  P201-P202-P280-P308+P313-P405-P501
RIDADR  2588
HazardClass  6.1(b)
PackingGroup  III

MILBEMECTIN A4 Chemical Properties,Uses,Production

Description

Milbemycin A4 is the prominent member of a complex family of macrocyclic lactones that contain a characteristic spiroketal group produced from the fermentation of soil bacterium S. hygroscopicus subsp. aureolacrimosus. As a compound that potentiates glutamate and GABA-gated chloride-channel opening, milbemycin 4 is used as a nematocide and insecticide.

Uses

Milbemycins are a complex family of macrocyclic lactones containing a highly characteristic spiroketal group, produced by Streptomyces hydroscopicus subsp. aureolarcrimosus. Milbemycin A4 is the dominant member of a group of analogues containing a 25-ethyl substituent. Milbemycin A4 is a highly selective and potent nematocide and insecticide. Like the closely related avermectins, milbemycins are thought to act on chloride-gated ion channels.

MILBEMECTIN A4 Preparation Products And Raw materials

MILBEMECTIN A4 Suppliers

Global( 64)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
Pharmaffiliates Analytics and Synthetics P. Ltd +91-172-5066494 Haryana, India 6773 58 Inquiry
SynZeal Research Pvt Ltd +1 226-802-2078 Gujarat, India 6522 58 Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
Shanghai Longyu Biotechnology Co., Ltd. +8613917842738 China 2534 58 Inquiry
BOC Sciences 16314854226; +16314854226 United States 19743 58 Inquiry
Alfa Chemistry +1-5166625404 United States 21317 58 Inquiry
China National Standard Pharmaceutical Corporation Limited +8615391658522 China 11927 58 Inquiry
Wuhan Topule Biopharmaceutical Co., Ltd +8618327326525 China 8474 58 Inquiry
Aladdin Scientific +1-+1(833)-552-7181 United States 52927 58 Inquiry
Nantong Hanfang Biotechnology Co. , Ltd. 18616537568 China 30968 58 Inquiry
milbemycinb-1 MILBEMECTIN A4 milbemectine a4 milbemycin A4 (25R)-25-Ethyl-5β-hydroxy-5-demethoxy-28-O,6β-cyclomilbemycin B (6R,25R)-5-O-Demethyl-28-deoxy-6,28-epoxy-25-ethylmilbemycin B Antibiotic B-41A4 Milbemycin α3 B 41A4, MilbeMycin alpha3 VOZIAWLUULBIPN-WMKNSKLVSA-N Milbemycin Impurity 1(Milbemycin EP Impurity A) Milbemycin oxime A4 Milbemycin EP Imp A Milbemycin B, 5-O-demethyl-28-deoxy-6,28-epoxy-25-ethyl-, (6R,25R)- Milbemycin EP Impurity A (1R,4S,5'S,6R,6'R,8R,10E,13R,14E,16E,20R,21R,24S)-6'-ethyl-21,24-dihydroxy-5',11,13,22-tetramethylspiro[3,7,19-trioxatetracyclo[15.6.1.14,8.020,24]pentacosa-10,14,16,22-tetraene-6,2'-oxane]-2-one Milbemycin Oxime Impurity 1(Milbemycin Oxime EP Impurity A) 51596-11-3 C32H46O7