MilbeMycin A3 OxiMe

MilbeMycin A3 OxiMe Structure
CAS No.
114177-14-9
Chemical Name:
MilbeMycin A3 OxiMe
Synonyms
MilbeMycin A3 OxiMe;Milbemite Impurity 2;5-OxoMilbeMycin A3 oxiMe;5-ketomilbemycin A3 5-oxime;Milbemycin Impurity 10(Milbemycin A3 Oxime);Milbemycin B, 5-demethoxy-28-deoxy-6,28-epoxy-5-(hydroxyimino)-25-methyl-, (6R,25R)-
CBNumber:
CB72674901
Molecular Formula:
C31H43NO7
Molecular Weight:
541.68
MOL File:
114177-14-9.mol
MSDS File:
SDS
Modify Date:
2023/5/21 10:59:17

MilbeMycin A3 OxiMe Properties

storage temp. Store at -20°C
solubility DMF: 30 mg/ml; DMSO: 30 mg/ml; Ethanol: 30 mg/ml
form A crystalline solid

MilbeMycin A3 OxiMe Chemical Properties,Uses,Production

Description

Milbemycin A3 oxime is an anthelmintic, a derivative of milbemycin A3 , and a component of milbemycin oxide . It reduces the number of microfilariae of the heartworm D. immitis in the blood of naturally infested dogs by 85.2% when administered at a dose of 0.05 mg/kg. Formulations containing milbemycin A3 oxime, in combination with milbemycin A4 oxime, have been used in the treatment of parasitic infections in dogs.

Uses

Milbemycin A3 oxime is a semi-synthetic macrocyclic lactone prepared by the oxidation and oximation of a mixture of milbemycin A3. Milbemycin A3 oxime is the minor component (~30%) in the commercial product milbemycin oxime, marketed for endo- and exo-parasite infections. Like the other milbemycin/avermectins, milbemycin A3 oxime acts by opening glutamate sensitive chloride channels in neurons of invertebrates leading to paralysis by hyperpolarisation of these cells and signal transfer blocking.

MilbeMycin A3 OxiMe Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 34)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
SynZeal Research Pvt Ltd +1 226-802-2078 Gujarat, India 6522 58 Inquiry
Pharmaffiliates Analytics and Synthetics P. Ltd +91-172-5066494 Haryana, India 6773 58 Inquiry
BOC Sciences 16314854226; +16314854226 United States 19743 58 Inquiry
China National Standard Pharmaceutical Corporation Limited +8615391658522 China 11927 58 Inquiry
Aladdin Scientific +1-+1(833)-552-7181 United States 52927 58 Inquiry
Nantong Hanfang Biotechnology Co. , Ltd. 18616537568 China 30968 58 Inquiry
Cato Research Chemicals Inc. 020-81960175-877 18933936954 China 7738 58 Inquiry
Nanjing XiZe Biotechnology CO., Ltd. 025-58362220 15250997978 China 7774 55 Inquiry
Beijing I-puritech Science & Technology Co.,Ltd 13311015623 China 73 58 Inquiry
MilbeMycin A3 OxiMe 5-OxoMilbeMycin A3 oxiMe Milbemycin Impurity 10(Milbemycin A3 Oxime) 5-ketomilbemycin A3 5-oxime Milbemycin B, 5-demethoxy-28-deoxy-6,28-epoxy-5-(hydroxyimino)-25-methyl-, (6R,25R)- Milbemite Impurity 2 114177-14-9