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Ioversol

Ioversol Structure
CAS No.
87771-40-2
Chemical Name:
Ioversol
Synonyms
Optiray;Loversol;P 530;mp-328;oversol;IOVERSOL;Iodophorol;Optiray 320;Ioversol API;Ioversol (200 mg)
CBNumber:
CB7374919
Molecular Formula:
C18H24I3N3O9
Molecular Weight:
807.11
MOL File:
87771-40-2.mol
Modify Date:
2023/5/18 11:31:12

Ioversol Properties

Melting point 180-182°C
Boiling point 864.9±65.0 °C(Predicted)
Density d37 1.371 (c = 320 mgI/ml)
storage temp. Refrigerator
solubility DMSO (Sparingly), Methanol (Slightly)
pka 11.34±0.46(Predicted)
form Solid
color White to Off-White
CAS DataBase Reference 87771-40-2(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

HS Code  2924296000
Toxicity LD50 in mice, rats, rabbits, dogs (gI/kg): 17, 15, >25, >12 i.v.; in male, female rats (mgI/kg): 1000, >1200 intracisternally (Ralston)

Ioversol Chemical Properties,Uses,Production

Chemical Properties

White Solid

Uses

Nonionic, low osmolality, radiographic contrast agent. Diagnostic aid (radiopaque medium).

Uses

Loversol is a radiopaque contrast agent. Ioversol contains iodine, a substance that absorbs x-rays. Contrast agents are used to allow blood vessels, organs, and other non-bony tissues to be seen more clearly on a CT scan or other radiologic (x-ray) examination.

Definition

Loversol is classified as an organoiodine compound and is used as a contrast dye in diagnostic procedures. It contains high levels of iodine in addition to various hydrophilic groups.

General Description

Ioversol is a low-osmolar, nonionicmonomer with 47% bound iodine content. It is indicated forangiography, excretory urography, ventriculography, andvarious CT procedures.

Side effects

The most common reaction is nausea, occurring at a rate of 1 percent.
Serious adverse reactions have been reported during post-approval use of Optiray. These serious adverse reactions include but are not limited to: anaphylactic reactions, arrhythmias, temporary blindness, tongue edema, seizures, respiratory arrest, bronchospasm, laryngeal spasm and thrombosis.

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6-triiodo-droxyethyl)amino)-4 mp-328 Ioversol (200 mg) N,N'-bis(2,3-dihydroxypropyl)-5-[(hydroxyacetyl)(2-hydroxyethyl)aMino]-2 oversol 1,3-benzenedicarboxamide,n,n’-bis(2,3-dihydroxypropyl)-5-((hydroxyacetyl)(2-hy 1,3-Benzenedicarboxamide, N,N'-bis(2,3-dihydroxypropyl)-5-[(hydroxyacetyl)(2-hydroxyethyl)amino]-2,4,6-triiodo- Optiray 320 P 530 P 530 (contrast agent) N,N'-Bis(2,3-dihydroxypropyl)-5-[N-(2-hydroxyethyl)-glycola mido]-2,4,6-triiodoisophthalamide N,N'-Bis(2,3-dihydroxypropyl)-5-[(2-hydroxyethyl)(hydroxyacetyl)amino]-2,4,6-triiodoisophthalamide n,n'-bis(2,3-dihydroxypropyl)-5-[(2-hydroxyacetyl)-(2-hydroxyethyl)amino]-2,4,6-triiodo-benzene-1,3-dicarboxamide IOVERSOL 3,4,5-triphenylcyclopent-3-ene-1,2-dione Ioversol (MP-328) 1,3-Benzenedicarboxamide, N1,N3-bis(2,3-dihydroxypropyl)-5-[(2-hydroxyacetyl)(2-hydroxyethyl)amino]-2,4,6-triiodo- N1,N3-bis(2,3-dihydroxypropyl)-5-(2-hydroxy-N-(2-hydroxyethyl)acetamido)-2,4,6-triiodoisophthalamide Ioversol USP/EP/BP Ioversolum [Latin] IoversolQ: What is Ioversol Q: What is the CAS Number of Ioversol Q: What is the storage condition of Ioversol Q: What are the applications of Ioversol Ioversol API Ioversol (1345104) Optiray Loversol Lactic acid 50-21-5 Iodophorol 87771-40-2 C18H24I3N3O9 Amines Aromatics Diagnostic Intermediates & Fine Chemicals Pharmaceuticals