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N1,N3-Bis(1,3-dihydroxypropan-2-yl)-5-(2-hydroxypropanamido)-2,4,6-triiodoisophthalamide

N1,N3-Bis(1,3-dihydroxypropan-2-yl)-5-(2-hydroxypropanamido)-2,4,6-triiodoisophthalamide Structure
CAS No.
62883-00-5
Chemical Name:
N1,N3-Bis(1,3-dihydroxypropan-2-yl)-5-(2-hydroxypropanamido)-2,4,6-triiodoisophthalamide
Synonyms
Iodopanol;Iopamidol CRS;Iodine, alcohol;2-[2-[(7-chloro-4-quinazolinyl)amino]ethoxy]ethanol;N,N'-bis(2-hydroxy-1-methylol-ethyl)-2,4,6-triiodo-5-lactamido-isophthalamide;N1,N3-Bis(1,3-dihydroxypropan-2-yl)-5-(2-hydroxypropanamido)-2,4,6-triiodoisophthalamide;N,N'-BIS(1,3-DIHYDROXYPROPAN-2-YL)-5-(2-HYDROXYPROPANOYLAMINO)-2,4,6-TRIIODO-BENZENE-1,3-DICARBOXAMIDE;N1,N3-bis(1,3-dihydroxypropan-2-yl)-5-(2-hydroxypropanoylamino)-2,4,6-triiodo-benzene-1,3-dicarboxamide;1-N,3-N-bis(1,3-dihydroxypropan-2-yl)-5-(2-hydroxypropanoylamino)-2,4,6-triiodobenzene-1,3-dicarboxamide;(S)-N,N'-bis[2-hydroxy-1-(hydroxymethyl)ethyl]-5-[(2-hydroxy-1-oxopropyl)amino]-2,4,6-triiodoisophthaldiamide
CBNumber:
CB8384797
Molecular Formula:
C17H22I3N3O8
Molecular Weight:
777.09
MOL File:
62883-00-5.mol
MSDS File:
SDS
Modify Date:
2023/5/4 17:34:40

N1,N3-Bis(1,3-dihydroxypropan-2-yl)-5-(2-hydroxypropanamido)-2,4,6-triiodoisophthalamide Properties

Melting point >283oC (dec.)
storage temp. -20°C Freezer, Under inert atmosphere
solubility Water (Slightly)
form Solid
pka pKa 10.70(H2O,t = 25.0) (Uncertain)
color White
CAS DataBase Reference 62883-00-5(CAS DataBase Reference)

N1,N3-Bis(1,3-dihydroxypropan-2-yl)-5-(2-hydroxypropanamido)-2,4,6-triiodoisophthalamide Chemical Properties,Uses,Production

Description

Lopamidol is a benzenedicarboxamide compound having N-substituted carbamoyl groups at the 1- and 3-positions, iodo substituents at the 2-, 4- and 6-positions and a (2S)-2-hydroxypropanamido group at the 5-position. It has a role as a radioopaque medium, an environmental contaminant and a xenobiotic. Lopamidol is a Radiographic Contrast Agent, it is a benzenedicarboxamide, an organoiodine compound and a pentol.

Uses

Diagnostic aid (radiopaque medium.

Uses

Lopamidol is a radiopaque (RAY dee oh payk) contrast agent to help diagnose or find problems in the brain, heart, head, blood vessels, and other parts of the body. Iopamidol contains iodine, a substance that absorbs x-rays. Radiopaque contrast agents are used to allow blood vessels, organs, and other non-bony tissues to be seen more clearly on a CT scan or other radiologic (x-ray) examination.

Indications

Iopamidol is indicated for angiography throughout the cardiovascular system in adults, including cerebral and peripheral arteriography, coronary arteriography and ventriculography, selective visceral arteriography and aortography, peripheral venography (phlebography), and in pediatric patients for angiocardiography; or for intravenous use in adult and pediatric for computed tomographic (CT) imaging of the head and body.

brand name

Isovue (Bracco).

Side effects

Serious Effects: Decreased urination, severe headache, dizziness, convulsion, irregular heart beat, feeling light-headed, fainting, breathing trouble, fever, chills, nausea and vomiting.
Local: Pain, tenderness, redness or skin changes.
Less Common: Joint or muscle pain, back ache, stiff neck, numbness, warmth, or tingly feeling, ringing in the ears, increased sweating, itchy skin, chills, stuffy nose, sneezing, confusion, slurred speech.

N1,N3-Bis(1,3-dihydroxypropan-2-yl)-5-(2-hydroxypropanamido)-2,4,6-triiodoisophthalamide Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 149)Suppliers
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DIVI'S LABORATORIES LIMITED +91 (40) 6696 6300 New Delhi, India 21 58 Inquiry
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career henan chemical co +86-0371-86658258 +8613203830695 China 29888 58 Inquiry
N,N'-BIS(1,3-DIHYDROXYPROPAN-2-YL)-5-(2-HYDROXYPROPANOYLAMINO)-2,4,6-TRIIODO-BENZENE-1,3-DICARBOXAMIDE N,N'-Bis(2-hydroxy-1-(hydroxymethyl)ethyl)-5-((2-hydroxy-1-oxopropyl)amino)-2,4,6-triiodo-1,3-Benzenedicarboxamide 1-N,3-N-bis(1,3-dihydroxypropan-2-yl)-5-(2-hydroxypropanoylamino)-2,4,6-triiodobenzene-1,3-dicarboxamide N,N'-bis(2-hydroxy-1-methylol-ethyl)-2,4,6-triiodo-5-lactamido-isophthalamide N1,N3-bis(1,3-dihydroxypropan-2-yl)-5-(2-hydroxypropanoylamino)-2,4,6-triiodo-benzene-1,3-dicarboxamide 1,3-BenzenedicarboxaMide,N1,N3-bis[2-hydroxy-1-(hydroxyMethyl)ethyl]-5-[(2-hydroxy-1-oxopropyl)aMino]-2,4,6-triiodo- 2-[2-[(7-chloro-4-quinazolinyl)amino]ethoxy]ethanol (S)-N,N'-bis[2-hydroxy-1-(hydroxymethyl)ethyl]-5-[(2-hydroxy-1-oxopropyl)amino]-2,4,6-triiodoisophthaldiamide Iopamidol CRS Iodine, alcohol Iodopanol N1,N3-Bis(1,3-dihydroxypropan-2-yl)-5-(2-hydroxypropanamido)-2,4,6-triiodoisophthalamide 62883-00-5 C17H22I3N3O8 Other APIs