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AURINTRICARBOXYLIC ACID

AURINTRICARBOXYLIC ACID Structure
CAS No.
4431-00-9
Chemical Name:
AURINTRICARBOXYLIC ACID
Synonyms
ATA;SKL331;e)-6-oxo-;aluminonfreeacid;TIMTEC-BB SBB005410;AURINTRICARBONIC ACID;aurintricarboxylicaci;LABOTEST-BB LT00080677;AURINTRICARBOXYLIC ACID;aurinetricarboxylic acid
CBNumber:
CB7463004
Molecular Formula:
C22H14O9
Molecular Weight:
422.34
MOL File:
4431-00-9.mol
MSDS File:
SDS
Modify Date:
2023/5/18 11:31:15

AURINTRICARBOXYLIC ACID Properties

Melting point 300 °C(lit.)
Boiling point 458.99°C (rough estimate)
Density 1.3860 (rough estimate)
refractive index 1.6230 (estimate)
storage temp. +15C to +30C
solubility 1  M NH4OH: 10 mg/mL
form powder
pka 2.20±0.20(Predicted)
color dark red to brown
Water Solubility Insoluble in water.
BRN 2228904
CAS DataBase Reference 4431-00-9(CAS DataBase Reference)
EPA Substance Registry System Benzoic acid, 5-[(3-carboxy-4-hydroxyphenyl)(3-carboxy-4-oxo-2,5-cyclohexadien-1-ylidene)methyl]-2-hydroxy- (4431-00-9)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P280a-P304+P340-P305+P351+P338-P405-P501a
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36
WGK Germany  3
RTECS  GU4790000
TSCA  Yes
NFPA 704
0
2 0

AURINTRICARBOXYLIC ACID price More Price(6)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) A1895 Aurintricarboxylic acid practical grade, ≥85% (titration), powder 4431-00-9 5G ₹4286.7 2022-06-14 Buy
Sigma-Aldrich(India) A1895 Aurintricarboxylic acid practical grade, ≥85% (titration), powder 4431-00-9 25G ₹13628.68 2022-06-14 Buy
Sigma-Aldrich(India) 189400 Aurintricarboxylic Acid - CAS 4431-00-9 - Calbiochem A cell-permeable polyanionic, polyaromatic compound used as a powerful inhibitor of cellular processes that are dependent on the formation of protein- 4431-00-9 100MG ₹5880 2022-06-14 Buy
ALFA India ALF-A15905-22 Aurintricarboxylic acid 4431-00-9 100g ₹52155 2022-05-26 Buy
ALFA India ALF-A15905-14 Aurintricarboxylic acid 4431-00-9 25g ₹13442 2022-05-26 Buy
Product number Packaging Price Buy
A1895 5G ₹4286.7 Buy
A1895 25G ₹13628.68 Buy
189400 100MG ₹5880 Buy
ALF-A15905-22 100g ₹52155 Buy
ALF-A15905-14 25g ₹13442 Buy

AURINTRICARBOXYLIC ACID Chemical Properties,Uses,Production

Chemical Properties

deep red coarse crystalline powder

Uses

Aurintricarboxylic acid is employed as a powerful inhibitor of cellular processes, including apoptosis, that are dependent on the formation of protein-nucleic acid complexes. It binds to a FGF and reduces its angiogenic activity. Aurintricarboxylic Acid has been shown to inhibit apoptotic cell death in various cell types induced by a variety of factors. It Inhibits protein-nucleic acid interactions. It stimulates the tyrosine phosphorylation of MAP kinases.

Definition

ChEBI: A member of the class of quinomethanes that is 3-methylidene-6-oxocyclohexa-1,4-diene-1-carboxylic acid in which the methylidene hydrogens are replaced by 4-carboxy-3-hydroxyphenyl groups. The trisodium salt is the biological stain 'chrome violet CG' while the triammonium salt is 'aluminon'.

Purification Methods

The acid is dissolved in aqueous NaOH, NaHSO3 solution is added until the colour is discharged and then the tricarboxylic acid is precipitated with HCl. [Heisig & Lauer Org Synth Coll Vol I 54 1941, Beilstein 10 IV 4161]. Do not extract the acid with hot water because it softens, forming a viscous mass. Make a solution in aqueous NH3. Aluminon is the NH4 salt.

AURINTRICARBOXYLIC ACID Preparation Products And Raw materials

Global( 124)Suppliers
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CHEMSWORTH +91-261-2397244 New Delhi, India 6707 30 Inquiry
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LEAPCHEM CO., LTD. +86-852-30606658 China 43348 58 Inquiry
TIMTEC-BB SBB005410 LABOTEST-BB LT00080677 ATA 5,5-(3-carboxy-4-oxocyclohexa-2,5-dienylidenemethylene)di(salicylic acid) aurinetricarboxylic acid AURINTRICARBOXYLIC ACID FREE ACIDPRACTIC AL GRADE Aurintricarboxylic Acid (Ata) AURINTRICARBONIC ACID Aurintricarboxylic acid, tech., 85% 1-Oxo-4-[bis(3-carboxy-4-hydroxyphenyl)methylene]-2,5-cyclohexadiene-2-carboxylic acid 5,5'-[(3-Carboxy-4-oxo-2,5-cyclohexadien-1-ylidene)methylene]bis(2-hydroxybenzoic acid) Aurintricarboxylic acid,85%,tech. 5,5'-((3-carboxy-4-oxocyclohexa-2,5-dien-1-ylidene)Methylene)bis(2-hydroxybenzoic acid) AURINTRICARBOXYLIC ACID 1,4-cyclohexadiene-1-carboxylicacid,3-(bis(3-carboxy-4-hydroxyphenyl)methylen 5-[(3-carboxy-4-hydroxyphenyl)(3-carboxy-4-oxo-2,5-cyclohexadien-benzoicaci aluminonfreeacid e)-6-oxo- 5,5'-((3-Carboxy-4-oxocyclohexa-2,5-dien-1-ylidene) bis(2-hydroxybenzoic acid) Benzoic acid, 3,3'-[(3-carboxy-4-oxo-2,5-cyclohexadien-1-ylidene)methylene]bis[6-hydroxy- aurintricarboxylicaci Aurintricarboxylic Acids (Technical Grade) SKL331 5-[(3-carboxy-4-hydroxyphenyl)-(3-carboxy-4-oxocyclohexa-2,5-dien-1-ylidene)methyl]-2-hydroxybenzoic acid Aurintricarboxylic Acid - CAS 4431-00-9 - Calbiochem ATA(Aurintricarboxylic acid) 4431-00-9 C22H14O9 DNA metabolism DNA Repair Regulators BioChemical Cell Signaling and Neuroscience Cell Biology Apoptosis and Cell Cycle Colours, Dyes, Indicators & Pigments