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ROSOLIC ACID

ROSOLIC ACID Structure
CAS No.
603-45-2
Chemical Name:
ROSOLIC ACID
Synonyms
AURIN;RosoL;AURINE;CORALLIN;CI 43800;AURIN GR;Nsc 7805;Aurin 555;Rosolic aci;CI NO 43800
CBNumber:
CB0296269
Molecular Formula:
C19H14O3
Molecular Weight:
290.31
MOL File:
603-45-2.mol
MSDS File:
SDS
Modify Date:
2023/5/4 17:34:40

ROSOLIC ACID Properties

Melting point 309°C (decompose)
Boiling point 372.4°C (rough estimate)
Density 1.2497 (rough estimate)
refractive index 1.4200 (estimate)
storage temp. Store at room temperature.
solubility Practically insoluble in water, benzene; freely soluble in ethanol
form Crystalline Powder
Colour Index 43800
pka 6.98(at 25℃)
color Red-brown to brownish-red
PH Range 6.8(YELLOW)--8.2(RED)
Water Solubility Soluble in alcohol, sodium hydroxide, potassium hydroxide and strong acids. Insoluble in water.
λmax 534.6nm, 479.5nm, 482nm
Merck 14,881
BRN 2055205
Stability Stable. Incompatible with strong oxidizing agents.
Major Application electrorheological materials, films patterning, antireflective coatings, thermochromic materials, photoresists, film patterning, recording materials, lithium battery, semiconductors, printing materials, inks, corrosion inhibitors, adhesives, drugs, detecting viable cells, treatment of Alzheimer’s disease
CAS DataBase Reference 603-45-2
EPA Substance Registry System 2,5-Cyclohexadien-1-one, 4-[bis(4-hydroxyphenyl)methylene]- (603-45-2)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P280a-P304+P340-P305+P351+P338-P405-P501a-P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313
Hazard Codes  Xi
Risk Statements  36/37/38-36/38
Safety Statements  26-36-37/39
WGK Germany  3
TSCA  Yes
HS Code  29145090
NFPA 704
1
2 0

ROSOLIC ACID price More Price(7)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) 861324 p-Rosolic acid Dye content 85?% 603-45-2 25G ₹11670 2022-06-14 Buy
Sigma-Aldrich(India) 861324 p-Rosolic acid Dye content 85?% 603-45-2 100G ₹48777.45 2022-06-14 Buy
ALFA India ALF-B21737-22 Rosolic acid 603-45-2 100g ₹15397 2022-05-26 Buy
ALFA India ALF-B21737-14 Rosolic acid 603-45-2 25g ₹4230 2022-05-26 Buy
TCI Chemicals (India) A0598 Pararosolic Acid 603-45-2 25G ₹5300 2022-05-26 Buy
Product number Packaging Price Buy
861324 25G ₹11670 Buy
861324 100G ₹48777.45 Buy
ALF-B21737-22 100g ₹15397 Buy
ALF-B21737-14 25g ₹4230 Buy
A0598 25G ₹5300 Buy

ROSOLIC ACID Chemical Properties,Uses,Production

Chemical Properties

red crystals or powder

Uses

Rosolic acid is used as a pH indicator in the range from 5.0 to 6.8. It acts as an intermediate in the manufacturing dyes. It is involved in the activation of heme oxygenase and in the inhibition of DNA fragmentation. It finds application in the selective isolation of coliform bacteria.

Purification Methods

It forms green crystals with a metallic luster, but the colour depends on the solvent used. When recrystallised from brine (saturated aqueous NaCl) acidified with HCl, it forms red needles, but when recrystallised from EtO/AcOH, the crystals have a beetle iridescent green colour. It has been recrystallised from Me2CO (although it dissolves slowly), methyl ethyl ketone, 80-95% AcOH and from AcOH/*C6H6. An aqueous KOH solution is golden yellow, and a 70% H2SO4 solution is deep red in colour. An alternative purification is to dissolve this triphenylmethane dye in 1.5% of aqueous NH3, filter, and heat to 70-80o, then acidify with dilute AcOH by adding it slowly with vigorous stirring, whereby the aurin separates as a brick-red powder or as purplish crystals depending on the temperature and period of heating. Filter off the solid, wash it with H2O and a little dilute AcOH, then H2O again. Stir this solid with Et2O to remove any ketones and allow it to stand overnight in the Et2O, then filter and dry it in air then in a vacuum. [Gomberg & Snow J Am Chem Soc 47 202 1925, Baines & Driver J Chem Soc 123 1216 1923, UV: Burawoy Chem Ber 64 462 1941, Beilstein 8 IV 2646.]

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4-[Bis(4-hydroxyphenyl)methylene]-2,5-cyclohexadienone, Aurin 4,4'-Dihydroxyfuchsone Corallin Spirit Soluble Spirit Aurin Rosolic acid (CI x 43800) 4-(p,p′-Dihydroxybenzhydrylidine)-2,5-cyclohexadien-1-one Corallin Aurin p-Rosolic Acid Rosolic aci 4-(bis(4-hydroxyphenyl)Methylene)cyclohexa-2,5-dienone PARAROSOLIC ACID P-ROSOLIC ACID 4-[bis(4-hydroxyphenyl)methylene]-5-cyclohexadien-1-one CORALLIN CORALLIN RED CORALLIN YELLOW CI NO 43800 CI 43800 LABOTEST-BB LT00847601 AURIN AURINE 4-(Bis(4-hydroxyphenyl) cyclohexa-2,5-dienone 4-[BIS(4-HYDROXYPHENYL)METHYLENE]-2,5-CYCLOHEXADIEN-1-ONE 4-[BIS(4-HYDROXYPHENYL)METHYLENE]-2,5-CYCLOHEXADIENONE 4-[BIS-(P-HYDROXYPHENYL)METHYLENE]-2,5-CYCLO-HEXADIEN-1-ONE ROSOLIC ACID INDICATOR ROSOLIC ACID (C.I. 43800) ROSOLIC ACID PRACTICAL GRADE ROSOLIC ACID C.I. 43800 INDICATOR FOR MICROSCOPY AURIN FOR MICROSCOPY (Rosolic Acid) C.I. No 43800 Para-ROSOLIC ACID INDICATOR AURIN (C.I. 43800) 4-[bis(p-hydroxyphenyl)methylene]cyclohexa-2,5-dien-1-one Roseolic acid AURIN GR RHODIZONIC ACID Dihydrate(P) 2,5-cyclohexadien-1-one, 4-[bis(p-hydroxyphenyl)methylene]- 4-(p,p′-dihydroxybenzhydrylidene)-2,5-cyclohexadien-1-one 4-[bis(p-hydroxy- Aphenyl)methylene]-2,5-cyclohexadien-1-one Aurin 555 Nsc 7805 Rosalic Acid Spirit Aurine 2,5-Cyclohexadien-1-one, 4-bis(4-hydroxyphenyl)methylene- Aurine、Pararosolic acid p-Rosolic acid, indicator Aurin (p-rosolic acid) RosoL 4-[bis(4-hydroxyphenyl)methylidene]cyclohexa-2,5-dien-1-one Rosolic acid pH indicator solution ROSOLIC ACID USP/EP/BP Rosonic acid, indicator TIANFUCHEM--High purity ROSOLIC ACID factory price p-ROSOLIC ACID INDICATOR For Microscopy 4-(Bis(4-hydroxyphenyl)methylene)cyclohexa-2,5-dien-1-one AURIN (p-ROSALIC ACID) 603-45-2 C19H14O3