Actarit
- CAS No.
- 18699-02-0
- Chemical Name:
- Actarit
- Synonyms
- Orcl;ms932;Mover;FAM79A;TPRG1L;ACTARIT;Ake him;Aktalin;Mirabegron M9;Protein FAM79A
- CBNumber:
- CB7732469
- Molecular Formula:
- C10H11NO3
- Molecular Weight:
- 193.2
- MOL File:
- 18699-02-0.mol
- MSDS File:
- SDS
- Modify Date:
- 2023/5/18 11:31:06
| Melting point | 173-175°C |
|---|---|
| Boiling point | 449.1±28.0 °C(Predicted) |
| Density | 1.288±0.06 g/cm3(Predicted) |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | DMSO, Ethanol, Methanol |
| form | Solid |
| pka | 4.34±0.10(Predicted) |
| color | White to Off-White |
| Merck | 14,133 |
| CAS DataBase Reference | 18699-02-0(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
| Safety Statements | 24/25 |
| RTECS | CY1542000 |
| HS Code | 29163990 |
| Toxicity | LD50 in male, female mice, male, female rats (mg/kg): 1.06, 1.30, 1.95, 2.03 i.p.; 5.68, 5.48, 5.48, 6.12 s.c.; 15.3, 14.7, 14.8, 15.4 orally (Toshida) |
Actarit Chemical Properties,Uses,Production
Description
Actarit is an orally administered disease-modifying antirheumatic drug launched in Japan. Although its structure resembles that of non-steroidal anti-inflammatory drugs, it has no effect on experimental acute inflammation and has no analgesic or antipyretic effects. Its preventative and therapeutic effects on adjuvant arthritis are mediated via modulation of production and serum level of interleukin-2 which enhances production of suppressor T-cells to the immune system, thereby, preventing development of articular lesions.
Chemical Properties
Crystalline Solid
Uses
Antiarthritic
Purification Methods
Crystallise the acid from MeOH/Me2CO, aqueous EtOH or H2O. The amide has m 231o (from 50% aqueous EtOH). [Gabriel Chem Ber 15 841 1882, Cerecedo et al. J Biol Chem 42 238 1924, Tramontano et al. J Am Chem Soc 110 2282 1988, Beilstein 14 II 281.]
Actarit Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 198)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| Varanous Labs Pvt Ltd | +91-7036248882 +91-7036248882 | Hyderabad, India | 1541 | 58 | Inquiry |
| BASR Fine Chemicals Pvt. Ltd. | +91-9848230391 +91-9848230391 | Telangana, India | 908 | 58 | Inquiry |
| TCI Chemicals (India) Pvt. Ltd. | 1800 425 7889 | New Delhi, India | 6778 | 58 | Inquiry |
| SynZeal Research Pvt Ltd | +1 226-802-2078 | Gujarat, India | 6522 | 58 | Inquiry |
| Pharmaffiliates Analytics and Synthetics P. Ltd | +91-172-5066494 | Haryana, India | 6773 | 58 | Inquiry |
| VIVAN Life Sciences Pvt. Limited. | +91(22) 2544 4584 / 2544 4585 | New Delhi, India | 138 | 50 | Inquiry |
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
| A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
| Hangzhou FandaChem Co.,Ltd. | 008657128800458; +8615858145714 | China | 9338 | 55 | Inquiry |
| Xiamen AmoyChem Co., Ltd | +86-592-6051114 +8618959220845 | China | 6387 | 58 | Inquiry |
18699-02-0(Actarit)Related Search:
Acetaminophen
4-Hydroxyphenylacetic acid
4-Methoxyphenylacetic acid
2-Hydroxyphenylacetic acid
ALPHA-METHYL-P-[1-OXO-2-ISOINDOLINYL]-BENZENEACETIC ACID
dexindoprofen
7-Diethylamino-3-(4'-maleimidylphenyl)-4- methylcoumarin
Phenylacetic acid
Indobufen
4-Aminophenylacetic acid
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1of4
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4-(acetylamino)-benzeneacetic acid
[4-(ACETYLAMINO)PHENYL]ACETIC ACID
(p-acetamidophenyl)-aceticaci
(p-acetamidophenyl)aceticacid
4-(acetylamino)-benzeneaceticaci
4-n-acetylaminophenylaceticacid
ms932
RARECHEM AL BO 1520
4-ACETAMIDO-PHENYLACETIC ACID
ACTARIT
Mover
Orcl
ANTI-TPRGL (N-TERM) antibody produced in rabbit
FAM79A
Mossy fiber terminal-associated vertebrate-specific presynaptic protein
Protein FAM79A
TPRG1L
Tumor protein p63-regulated gene 1-like protein
Mirabegron M9 (YM-340790)
4-Acetamido-phenylacetic acid ,97%
O-(Carboxymethyl)paracetamol
p-Acetylaminophenylacetic acid
N-acetyl-4-aMinophenyl-acetic acid
ActaritIn-houseStandard
AKETALI (ACTARIT)
Mirabegron M9
Benzeneaceticacid, 4-(acetylamino)-
2-(4-acetamidocyclohexyl)acetate
Actarit USP/EP/BP
Mirabegron-metabolite M9
Ake him
2-(4-acetamidophenyl)aceticaci
Aktalin
18699-02-0
Aromatic Phenylacetic Acids and Derivatives
Aromatics
Intermediates & Fine Chemicals
Pharmaceuticals