GLYCOFUROL
- CAS No.
- 31692-85-0
- Chemical Name:
- GLYCOFUROL
- Synonyms
- TETRAGLYCOL;THFP;GLYCOFUROL;TETRAGLYCO;Glycofural;Glycofurol75;Glycofurolum 75;GLYCOFUROL-SPECIAL;GLYCOFUROL TETRAGLYCOL;Tetraglycol ( Glycofurol)
- CBNumber:
- CB7756948
- Molecular Formula:
- C11H21O5R
- Molecular Weight:
- 233.28
- MOL File:
- 31692-85-0.mol
- MSDS File:
- SDS
- Modify Date:
- 2023/5/25 17:51:41
| Boiling point | 100-145 °C0.4 mm Hg |
|---|---|
| Density | 1.09 g/mL at 25 °C(lit.) |
| vapor pressure | 4.97-37.4Pa at 20-50℃ |
| refractive index |
n |
| Flash point | >230 °F |
| storage temp. | Store below +30°C. |
| solubility | Chloroform (Sparingly), Methanol (Slightly, Sonicated) |
| form | Oil |
| color | Colourless |
| Stability | Stable. Combustible. Incompatible with strong oxidizing agents. |
| LogP | -1.21--0.38 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H319 |
| Precautionary statements | P264-P280-P305+P351+P338-P337+P313 |
| WGK Germany | 3 |
| RTECS | MD0907500 |
| HS Code | 3907 20 20 |
GLYCOFUROL price More Price(8)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | T3396 | Tetraglycol BioXtra | 31692-85-0 | 100G | ₹5520.75 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | T3396 | Tetraglycol BioXtra | 31692-85-0 | 250G | ₹9796.63 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | T3396 | Tetraglycol BioXtra | 31692-85-0 | 1KG | ₹25590.3 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 8.21092 | Tetrahydrofurfuryl alcohol polyethylene glycol ether for synthesis | 31692-85-0 | 100ML | ₹4420 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 8.21092 | Tetrahydrofurfuryl alcohol polyethylene glycol ether for synthesis | 31692-85-0 | 250ML | ₹8260 | 2022-06-14 | Buy |
GLYCOFUROL Chemical Properties,Uses,Production
Chemical Properties
Glycofurol is a clear, colorless, almost odorless liquid, with a bitter taste; it produces a warm sensation on the tongue.
Uses
Glycofurol is used as a carrier device for drug delivery.
Production Methods
Glycofurol is prepared by the reaction of tetrahydrofurfuryl alcohol with ethylene oxide (followed by a special purification process in the case of Glycofurol 75).
Pharmaceutical Applications
Glycofurol is used as a solvent in parenteral products for intravenous or intramuscular injection in concentrations up to 50% v/v. It has also been investigated, mainly in animal studies, for use as a penetration enhancer and solvent in topical and intranasal formulations. Glycofurol has also been used at 20% v/v concentration in a rectal formulation.
Safety
Glycofurol is mainly used as a solvent in parenteral pharmaceutical
formulations and is generally regarded as a relatively nontoxic and
nonirritant material at the levels used as a pharmaceutical excipient.
Glycofurol can be irritant when used undiluted; its tolerability is
approximately the same as propylene glycol.
Glycofurol may have an effect on liver function and may have a
low potential for interaction with hepatoxins or those materials
undergong extensive hepatic metabolism.
LD50 (mouse, IV): 3.5 mL/kg
storage
Stable if stored under nitrogen in a well-closed container protected from light, in a cool, dry place.
Incompatibilities
Incompatible with oxidizing agents.
Regulatory Status
Included in parenteral medicines licensed in Europe.
GLYCOFUROL Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| aistrifarma | +91-6374274350 +91-7708086868 | Tamil Nadu, India | 15 | 58 | Inquiry |
| JSK Chemicals | +919879767970 | Gujarat, India | 3756 | 58 | Inquiry |
| CHEMSWORTH | +91-261-2397244 | New Delhi, India | 6707 | 30 | Inquiry |
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
| Sisco Research Laboratories Pvt. Ltd. | +91-22-4268 5800 | Mumbai, India | 4317 | 58 | Inquiry |
| Triveni chemicals | 08048762458 | New Delhi, India | 6093 | 58 | Inquiry |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | China | 26216 | 58 | Inquiry |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | China | 21676 | 55 | Inquiry |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418679 +86-18949832763 | China | 2989 | 55 | Inquiry |
| Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | China | 39916 | 58 | Inquiry |
| Supplier | Advantage |
|---|---|
| aistrifarma | 58 |
| JSK Chemicals | 58 |
| CHEMSWORTH | 30 |
| CLEARSYNTH LABS LTD. | 58 |
| Sisco Research Laboratories Pvt. Ltd. | 58 |
| Triveni chemicals | 58 |
| Dideu Industries Group Limited | 58 |
| Henan Tianfu Chemical Co.,Ltd. | 55 |
| Hefei TNJ Chemical Industry Co.,Ltd. | 55 |
| Chongqing Chemdad Co., Ltd | 58 |
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