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Monensin

Monensin Structure
CAS No.
17090-79-8
Chemical Name:
Monensin
Synonyms
MONENSIN SODIUM;a3823a;monelan;MONENSIN;Romensin;elancoban;Monensin A;MONENSIN NA;Monensin 20%;monensicacid
CBNumber:
CB9748019
Molecular Formula:
C36H62O11
Molecular Weight:
670.87
MOL File:
17090-79-8.mol
MSDS File:
SDS
Modify Date:
2024/7/24 17:31:20

Monensin Properties

Melting point 103-105°C
alpha D +47.7°
Boiling point 608.24°C (rough estimate)
Density 1.0773 (rough estimate)
refractive index 1.5465 (estimate)
storage temp. 2-8°C
pka 6.6 (in 66% DMF)
CAS DataBase Reference 17090-79-8(CAS DataBase Reference)
EPA Substance Registry System Monensin (17090-79-8)

SAFETY

Risk and Safety Statements

Hazard Codes  T
Risk Statements  25
Safety Statements  36/37/39-45
WGK Germany  3
RTECS  JH2830000
Toxicity LD50 of monensin complex in mice, chicks (mg/kg): 43.8 ± 5.2, 284 ± 47 orally (Haney, Hoehn)

Monensin Chemical Properties,Uses,Production

Description

Monensin was found in the mycelium of Streptomyces cinnamonensis by Eli Lilly & Co. in 1967 in the course of screening for anticoccidial and growth-promoting substances for cattle, swine, and chickens. It shows antiprotozoal, antibacterial, and antifungal activities, as well as anticoccidial activity. Monensin is widely used to treat such infections and as a feed additive to promote the growth of livestock.

Chemical Properties

Crystallin Solid

Uses

Monensin A is a polyether antibiotic first isolated from Streptomyces cinnamonensis in 1967. Monensin A is a broad-spectrum anticoccicidial antibiotic, also exhibiting antifungal and antiviral activity. Monensin A forms complexes with monovalent cations such as Li+, Na+, K+, Rb+, Ag+ and Tl+ and is thus able to transport these cations across lipid membranes of cells, playing an important role as an Na+/H+ antiporter. It blocks intracellular protein transport and is used in animals to prevent coccidiosis, promote growth and prevent bloat. Derivatives of monensin, monensin methyl ester and particularly monensin decyl ester, are used in ion selective electrodes.

Safety Profile

Poison by ingestion and intraperitoneal routes. An eye and skin irritant. When heated to decomposition it emits acrid smoke and irritating fumes.

Monensin Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 207)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
Pharmaffiliates Analytics and Synthetics P. Ltd +91-172-5066494 Haryana, India 6773 58 Inquiry
Pandora Industries Private Limited 08048966804 Delhi, India 9 58 Inquiry
SynZeal Research Pvt Ltd +1 226-802-2078 Gujarat, India 6522 58 Inquiry
Pharma Affiliates 172-5066494 Haryana, India 6761 58 Inquiry
XI'AN TIANGUANGYUAN BIOTECH CO., LTD. +86-029-86333380 18829239519 China 918 58 Inquiry
Hebei Guanlang Biotechnology Co,.LTD +86-19930503253; +8619930503252 China 5831 58 Inquiry
shandong perfect biotechnology co.ltd +86-53169958659; +8618596095638 China 294 58 Inquiry
Henan Fengda Chemical Co., Ltd +86-371-86557731 +86-13613820652 China 20296 58 Inquiry
Shaanxi TNJONE Pharmaceutical Co., Ltd +8618740459177 China 1142 58 Inquiry
2-(5-ethyltetrahydro-5-(tetrahydro-3-6-dioxaspiro(4.5)decane-7-butyricacid a3823a elancoban gamma,2,8-tetramethyl--furyl)-2-furyl)-9-hydroxy-beta-methoxy-alph monelan Monensine sodium 4-[2-[2-Ethyl-5-(6-hydroxy-6-hydroxymethyl-3,5-dimethyltetrahydropyran-2-yl)-3-methyloctahydro-[2,2]bifuranyl-5-yl]-9-hydroxy-2,8-dimethyl-1,6-dioxaspiro[4.5]dec-7-yl]-3-methoxy-2-methylpentanoic acid Monensin A 4-[2-(5-ethyl-5-{5-[6-hydroxy-6-(hydroxyMethyl)-3,5-diMethyloxan-2-yl]-3-Methyloxolan-2-yl}oxolan-2-yl)-9-hydroxy-2,8-diMethyl-1,6-dioxaspiro[4.5]decan-7-yl]-3-Methoxy-2-Methylpentanoic acid Monensin 20% Monensic acid, Lilly 67314, A 3223A. Monensin premix MONENSIN NA MONENSIN A SODIUM SALT MONENSIN monensicacid 4-[3-[5-ETHYL-5-[5-[6-HYDROXY-6-(HYDROXYMETHYL)-3,5-DIMETHYL-TETRAHYDROPYRAN-2-YL]-3-METHYL-TETRAHYDROFURAN-2-YL]-TETRAHYDROFURAN-2-YL]-9-HYDROXY-3,8-DIMETHYL-4,6-DIOXASPIRO[4.5]DEC-7-YL]-3-METHOXY-2-METHYL-PENTANOATE 2-[5-Ethyltetrahydro-5-[tetrahydro-3-methyl-5-[tetrahydro-6-hydroxy-6-(hydroxymethyl)-3,5-dimethyl-2H-pyran-2-yl]-2-furyl]-2-furyl]-9-hydroxy-beta-methoxy-alpha,gamma,2,8-tetramethyl-1,6-dioxaspiro[4.5]decane-7-butyric acid Romensin 2-[5-Ethyltetrahydro-5-[tetrahydro-3-methyl-5-[tetrahydro-6-hydroxy-6-(hydroxymethyl)-3,5-dimethyl-2H-pyran-2-yl]-2-furyl]-2-furyl]-9-hydroxy--methoxy-a,,2,8-tetramethyl-1,6-dioxaspiro[4.5]decane-7-butyric Acid MONENSIN(PURE) MONENSINSODIUMSALT(30%) Monensin:Monesin Sodium Monensin USP/EP/BP 17090-79-8 Monensin MONENSIN SODIUM 17090-79-8 2411-54-0 C36H61O11Na C36H62O11 C37H63NaO10 Chiral Reagents Intermediates & Fine Chemicals Pharmaceuticals API's