Cisatracurium besylate
![Cisatracurium besylate Structure](CAS/GIF/96946-42-8.gif)
- CAS No.
- 96946-42-8
- Chemical Name:
- Cisatracurium besylate
- Synonyms
- Cisatracurium;cisatracurium besilate;NiMbex;1 kg - 1.5kg;Cis-AttacuriuM;Mikhail Zayats;(1R,1'R,2R,2'R)-;Cisatracurium besyL;Cisatracurium besyla;Cisatrcurium Besylate
- CBNumber:
- CB7855410
- Molecular Formula:
- C53H72N2O12.2C6H5O3S
- Molecular Weight:
- 1243.49
- MOL File:
- 96946-42-8.mol
- Modify Date:
- 2024/8/21 22:41:43
Cisatracurium besylate Chemical Properties,Uses,Production
Description
Cisatracurium besylate is a new intermediate-duration non-depolarizing muscle relaxant launched in the U.S.A. for intubation and maintenance of muscle relaxation during surgery and intensive care. Cisatracurium besylate is the single 1 R cis-1'R cis isomer of the commercial preparation of atracurium, a mixture of 10 isomers. It is 3 to 5 times more potent than the mixture with similar onset and duration of action. The single isomer was also reported to have reduced propensity to release histamine and have a stable cardiovascular profile. Similar to structurally related mivacurium, cisatracurium has distinct advantages of rapid degradation, enzymatic metabolism that is independent of liver or kidney resulting in short duration of action and fast, complete recovery.
Chemical Properties
White Solid
Uses
Cisatracurium Besylate is a nondepolarizing neuromuscular blocking agent, antagonizing the action of acetylcholine by inhibiting neuromuscular transmission.
Definition
ChEBI: The (1R,1'R,2R,2'R)-diastereoisomer of atracurium besylate. Commercial preparations of atracurium are mixtures of 10 stereoisomers, of which cisatracurium generally constitutes about 15%. isatracurium besylate is about 3 times more potent than the mixture of atracurium isomers as a neuromuscular blocking agent, and is used as a muscle relaxant for endotracheal intubation, to aid controlled ventilation, and in general anaesthesia.
Cisatracurium besylate Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | Inquiry |
---|---|---|---|---|---|
Gland Pharma Ltd | +91-7075736524 +91-9700602423 | Telangana, India | 44 | 58 | Inquiry |
Synnat Pharma Pvt Ltd | +91-9966980001 +91-9989984964 | AndhraPradesh, India | 22 | 58 | Inquiry |
VIVAN Life Sciences Pvt. Limited. | +91(22) 2544 4584 / 2544 4585 | New Delhi, India | 138 | 50 | Inquiry |
GLAND PHARMA LTD | +91-40-30510999 | New Delhi, India | 52 | 58 | Inquiry |
A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
SynZeal Research Pvt Ltd | +1 226-802-2078 | Gujarat, India | 6522 | 58 | Inquiry |
Pharmaffiliates Analytics and Synthetics P. Ltd | +91-172-5066494 | Haryana, India | 6773 | 58 | Inquiry |
Triveni chemicals | 08048762458 | New Delhi, India | 6093 | 58 | Inquiry |
Louis Pharmaceuticals Private Limited | 08068441157Ext 357 | Telangana, India | 17 | 58 | Inquiry |
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