Nemadectin

Nemadectin Structure
CAS No.
102130-84-7
Chemical Name:
Nemadectin
Synonyms
AC-088;Nemadectin;LL-F-28249α;LL-F28249 alpha;S541A, LL-F28249 alpha;(6R,23S,25S)-5-O-Demethyl-28-deoxy-25-[(E)-1,3-dimethyl-1-butenyl]-6,28-epoxy-23-hydroxymilbemycin B;Milbemycin B,5-O-demethyl-28-deoxy-25-[(1E)-1,3-dimethyl-1-buten-1-yl]-6,28-epoxy-23-hydroxy-,(6R,23S)-
CBNumber:
CB81179291
Molecular Formula:
C36H52O8
Molecular Weight:
612.79
MOL File:
102130-84-7.mol
MSDS File:
SDS
Modify Date:
2024/7/2 8:55:17

Nemadectin Properties

alpha D26 +133° (c = 0.3 in acetone)
Boiling point 789.4±60.0 °C(Predicted)
Density 1.20±0.1 g/cm3(Predicted)
pka 12.46±0.70(Predicted)
form Solid
color White to off-white

SAFETY

Risk and Safety Statements

RIDADR  2588
HazardClass  6.1(b)
PackingGroup  III

Nemadectin Chemical Properties,Uses,Production

Description

The nemadectins are fermentation products of Streptomyces cyaneogriseus noncyanogenus. Structurally, the nemadectins lack a disaccharide group at C-13 but differ from the milbemycins proper because they contain a trisubstituted double bond at C-26 in their side chains.

Uses

Nemadectin is the dominant member of a class of milbemycins bearing unsaturated longer chain groups at the 25-position. Nemadectin shows pronounced nematocidal and insecticidal activity. Nemadectin is the starting material for moxidectin, a commercial anthelmintic.

Nemadectin Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 69)Suppliers
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Nemadectin (6R,23S,25S)-5-O-Demethyl-28-deoxy-25-[(E)-1,3-dimethyl-1-butenyl]-6,28-epoxy-23-hydroxymilbemycin B AC-088 LL-F-28249α S541A, LL-F28249 alpha LL-F28249 alpha Milbemycin B,5-O-demethyl-28-deoxy-25-[(1E)-1,3-dimethyl-1-buten-1-yl]-6,28-epoxy-23-hydroxy-,(6R,23S)- 102130-84-7