ChemicalBook > Product Catalog >Analytical Chemistry >Standard >Standard Substance >N-DESMETHYLCLOZAPINE
N-DESMETHYLCLOZAPINE
- CAS No.
- 6104-71-8
- Chemical Name:
- N-DESMETHYLCLOZAPINE
- Synonyms
- NORCLOZAPINE;Desmethylclozapine;Norclozapine (ACP-104);Normethylclozapine;N-DESMETHYLCLOZAPINE;Clozapine EP IMpurity C;Clozapine Impurity C（EP）;N-Desmethylclozapine solution;Norclozapine Solution, 100ppm;Desmethylclozapine (Norclozapine)
- CBNumber:
- CB8196019
- Molecular Formula:
- C17H17ClN4
- Molecular Weight:
- 312.8
- MOL File:
- 6104-71-8.mol
- Modify Date:
- 2023/9/20 16:43:00
| Melting point | 120-125°C |
|---|---|
| Boiling point | 502.6±60.0 °C(Predicted) |
| Density | 1.38±0.1 g/cm3(Predicted) |
| Flash point | 9℃ |
| storage temp. | Store at RT |
| solubility | Chloroform (Slightly), DMSO, Methanol (Slightly) |
| pka | 8.49±0.10(Predicted) |
| form | Yellow solid. |
| color | Light Yellow to Yellow |
| CAS DataBase Reference | 6104-71-8(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302+H332-H315-H319-H335 | |||||||||
| Precautionary statements | P261-P264-P301+P312-P302+P352-P304+P340+P312-P305+P351+P338 | |||||||||
| Hazard Codes | Xn,T,F | |||||||||
| Risk Statements | 20/22-36/37/38-39/23/24/25-23/24/25-11 | |||||||||
| Safety Statements | 22-36-45-36/37-16-7 | |||||||||
| RIDADR | 3249 | |||||||||
| WGK Germany | 3 | |||||||||
| HazardClass | 6.1(b) | |||||||||
| PackingGroup | III | |||||||||
| NFPA 704 |
|
N-DESMETHYLCLOZAPINE price More Price(3)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | D5676 | N-Desmethylclozapine | 6104-71-8 | 5MG | ₹15966.88 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | D5676 | N-Desmethylclozapine | 6104-71-8 | 10MG | ₹23609.33 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | D-048 | N-Desmethylclozapine solution 1.0?mg/mL in methanol, ampule of 1?mL, certified reference material, Cerilliant? | 6104-71-8 | 1ML | ₹14616.7 | 2022-06-14 | Buy |
N-DESMETHYLCLOZAPINE Chemical Properties,Uses,Production
Chemical Properties
Yellow Crystalline Solid
Uses
N-Desmethylclozapine has been used as standard to quantify the clozapine plasma levels in treatment-refractory Chinese schizophrenic patients.
Definition
ChEBI: A dibenzodoazepine substituted with chloro and piperazino groups which is a major metabolite of clozapine; a potent and selective 5-HT2C serotonin receptor antagonist.
General Description
N-Desmethylclozapine is an active metabolite of Clozapine, an atypical antipsychotic drug used for treatment of schizophrenia. Clozapine is sold under the trade names Clozaril? and FrazaClo in the US. This Certified Snap-N-Spike? Solution is suitable for use in urine drug testing, clinical toxicology, forensic analysis, and clinical monitoring by LC-MS/MS or GC/MS.
Biological Activity
A major metabolite of clozapine; a potent and selective 5-HT 2C serotonin receptor antagonist.
N-DESMETHYLCLOZAPINE Preparation Products And Raw materials
Raw materials
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Global( 131)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| CLEANCHEM LABORATORIES LLP | +91-9951015911 +91-9951015911 | Mumbai, India | 281 | 58 | Inquiry |
| GLP Pharma Standards | +91 9866074638 | Hyderabad, India | 1644 | 58 | Inquiry |
| Varanous Labs Pvt Ltd | +91-7036248882 +91-7036248882 | Hyderabad, India | 1541 | 58 | Inquiry |
| SynZeal Research Pvt Ltd | +1 226-802-2078 | Gujarat, India | 6522 | 58 | Inquiry |
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
| Pharmaffiliates Analytics and Synthetics P. Ltd | +91-172-5066494 | Haryana, India | 6773 | 58 | Inquiry |
| JSK Chemical | 98797 67970 | Gujarat, India | 291 | 58 | Inquiry |
| Pharma Affiliates | 172-5066494 | Haryana, India | 6761 | 58 | Inquiry |
| Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | China | 29798 | 60 | Inquiry |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | China | 32760 | 60 | Inquiry |
6104-71-8(N-DESMETHYLCLOZAPINE)Related Search:
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N-DESMETHYLCLOZAPINE
8-CHLORO-11-(1-PIPERAZINYL)-5H-DIBENZO[B,E][1,4]DIAZEPINE
8-CHLORO-11-1[1-PIPERAZINYL)-5H-DIBENZO[B,E][1,4]DIAZEPINE
8-CHLORO-11-PIPERAZINYL-5H-DIBENZO[B,E][1,4]DIAZEPINE
CLOZAPINE, NORMETHYL(NORMETHYLCLOZAPINE, NOR-CLOZAPINE, DESMETHYLC
8-Chloro-11-piperazinyl-5H-dibenzo[b,e][1,4]diazepine, Norclozapine, Normethylclozapine
Normethylclozapine
5H-Dibenzo[b,e][1,4]diazepine, 8-chloro-11-(1-piperazinyl)-
Clozapine EP IMpurity C
N-Desmethylclozapine solution
N-Desmethyl Clozapine-d8 hydrochloride
8-Chloro-11-(piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine
Clozapine Impurity 3(Clozapine EP Impurity C)
Norclozapine Solution, 100ppm
NORCLOZAPINE; DESMETHYLCLOZAPINE; NORMETHYLCLOZAPINE
3-chloro-6-piperazin-1-yl-5H-benzo[b][1,4]benzodiazepine
Clozapine impurity 3/Clozapine EP Impurity C/Clozapine impurity A (USP)/8-chloro-11-(piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine
Desmethylclozapine (Norclozapine)
8-Chloro-11-(piperazin-1-yl)-5H-dib
Clozapine EP Impurity C (N-Desmethyl Clozapine)
Clozapine EP Impurity CQ: What is
Clozapine EP Impurity C Q: What is the CAS Number of
Clozapine EP Impurity C Q: What is the storage condition of
Clozapine EP Impurity C Q: What are the applications of
Clozapine EP Impurity C
NORCLOZAPINE
Desmethylclozapine
Norclozapine (ACP-104)
Clozapine Impurity C（EP）
6104-71-8
C17H17ClN4
3128
Various Metabolites and Impurities
Intermediates & Fine Chemicals
Metabolites & Impurities
Pharmaceuticals
Miscellaneous
Serotonin receptor